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anti-Basal Cell Adhesion Molecule (Lutheran Blood Group) (BCAM) Antibodies

BCAM encodes Lutheran blood group glycoprotein, a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. Additionally we are shipping BCAM Proteins (12) and BCAM Kits (10) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
BCAM 57278 Q9R069
BCAM 4059 P50895
BCAM 78958 Q9ESS6
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Top anti-BCAM Antibodies at antibodies-online.com

Showing 10 out of 41 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-BCAM Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: HepG2 cell lysate WB Suggested Anti-BCAM  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control: HepG2 cell lysate  BCAM is strongly supported by BioGPS gene expression data to be expressed in Human HepG2 cells 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated FACS, WB   0.2 mg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Antigen: 0.2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Goat-Anti-Rabbit IgG at 1: 5000; TMB staining; Read the data in MicroplateReader by 450 Formalin-fixed and paraffin embedded mouse spleen labeled with Rabbit Anti CD239 Polyclonal Antibody, Unconjugated (ABIN873081) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Mouse Un-conjugated FACS, WB   200 μg Log in to see 8 to 10 Days
$559.17
Details
Human Rabbit Un-conjugated IP, IHC (p), WB Immunochemical staining of human BCAM in human breast carcinoma with rabbit polyclonal antibody (1 µg/mL, formalin-fixed paraffin embedded sections). Positive staining was localized to the epithelia and endothelium. Immunochemical staining of human BCAM in human tonsil with rabbit polyclonal antibody (1 µg/mL, formalin-fixed paraffin embedded sections). Positive staining was localized to the endothelium of blood vessel walls. 100 μg Log in to see 16 Days
$218.90
Details
Rat Rabbit Un-conjugated IHC (p) Immunochemical staining of rat BCAM in rat kidney with rabbit polyclonal antibody (1 µg/mL, formalin-fixed paraffin embedded sections). 100 μg Log in to see 16 Days
$218.90
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 14 Days
$201.19
Details
Human Mouse Un-conjugated WB 100 μg Log in to see 2 to 3 Days
$319.00
Details
Human Rabbit Alexa Fluor 350 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details

BCAM Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) ,


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More Antibodies against BCAM Interaction Partners

Mouse (Murine) Basal Cell Adhesion Molecule (Lutheran Blood Group) (BCAM) interaction partners

  1. Lu/BCAM may have a critical role in facilitating the accumulation of monocytes and macrophages, thereby exacerbating renal injury in crescentic glomerulonephritis.

  2. Lutheran (Lu), also known as basal cell adhesion molecule (B-CAM), competes with integrins for binding to laminin alpha5, a subunit of LM-511, a major component of basement membranes.

  3. Lu/BCAM, as a laminin receptor, is involved in vivo in the maintenance of normal basement membrane organization in the kidney and intestine.

Human Basal Cell Adhesion Molecule (Lutheran Blood Group) (BCAM) interaction partners

  1. Cytometry analysis evidenced a specific expression profile on reticulocytes of SCA infants, with notably an increased expression of the adhesion molecules Lu/BCAM, ICAM-4 (show ICAM4 Antibodies) and LFA-3, both in percentage of positive cells and in surface density.

  2. Through molecular genotyping we also identified polymorphisms in RhCE (show RHCE Antibodies), Kell, Duffy, Colton, Lutheran and Scianna loci in donors and patients.

  3. The variable levels of expression of mutated JAK2 (show JAK2 Antibodies) and BCAM (show BCAT2 Antibodies) proteins determine different adhesion patterns of erythrocytes from polycythemia vera (show IGF2BP3 Antibodies) patients.

  4. These studies revealed amino acids 720 to 1014 of CNF1 as the binding site for Lu/BCAM.

  5. High BCAM (show BCAT2 Antibodies) expression is associated with hepatocellular carcinoma.

  6. Adhesion of sickle reticulocytes to HC-treated endothelial cells was decreased despite the HC-derived increase of Lu/BCAM expression.

  7. tumor cell migration on LM-511 requires that Lu/B-CAM competitively modulates cell attachment through integrins.

  8. DARC (show DARC Antibodies) and BCAM (show BCAT2 Antibodies) expression was associated with pathogenesis of thyroid carcinoma and correlated with clinical-pathological features.

  9. Glu425 in the Lu glycoprotein is required for expression of Lu7, and Ala425 is associated with the LU:-7 phenotype. This completes the molecular basis associated with all antigens known to be in the Lutheran blood group system.

  10. Increases in adhesion frequency provide significant evidence of the role of epinephrine in BCAM/Lu-laminin and ICAM-4 (show ICAM4 Antibodies)-alpha(v)beta(3) bonding, and suggest mechanisms of vaso-occlusion during physical exertion in sickle cell trait.

BCAM Antigen Profile

Protein Summary

This gene encodes Lutheran blood group glycoprotein, a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five extracellular immunoglobulin domains, a single transmembrane domain, and a short C-terminal cytoplasmic tail. This protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in sickle cell disease. Polymorphisms in this gene define some of the antigens in the Lutheran system and also the Auberger system. Inactivating variants of this gene result in the recessive Lutheran null phenotype, Lu(a-b-), of the Lutheran blood group. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with BCAM

  • basal cell adhesion molecule (Lutheran blood group) (bcam) antibody
  • basal cell adhesion molecule (Lutheran blood group) (BCAM) antibody
  • basal cell adhesion molecule (Bcam) antibody
  • basal cell adhesion molecule (Lutheran blood group) (Bcam) antibody
  • 1200005K12Rik antibody
  • AU antibody
  • B-CAM antibody
  • CD239 antibody
  • Gplu antibody
  • Lu antibody
  • MGC81012 antibody
  • MSK19 antibody
  • prr2 antibody
  • zgc:154034 antibody

Protein level used designations for BCAM

basal cell adhesion molecule (Lutheran blood group) , Auberger b antigen , Lutheran blood group , basal cell adhesion molecule (Lu and Au blood groups) , basal cell adhesion molecule , LU , basal cell adhesion molecule-like , B-CAM cell surface glycoprotein , lutheran antigen , lutheran glycoprotein , B-cell adhesion molecule , F8/G253 antigen , antigen identified by monoclonal antibody F8 , glycoprotein 95kDa , Lutheran blood group (Auberger b antigen included)

GENE ID SPECIES
100036718 Xenopus (Silurana) tropicalis
444320 Xenopus laevis
484456 Canis lupus familiaris
714568 Macaca mulatta
744276 Pan troglodytes
767689 Danio rerio
100070622 Equus caballus
100446557 Pongo abelii
100477918 Ailuropoda melanoleuca
57278 Mus musculus
4059 Homo sapiens
78958 Rattus norvegicus
282862 Bos taurus
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