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BHLHE41 encodes a transcription factor that belongs to the Hairy/Enhancer of Split subfamily of basic helix-loop-helix factors. Additionally we are shipping BHLHE41 Kits (12) and BHLHE41 Proteins (4) and many more products for this protein.
Showing 10 out of 92 products:
Human Polyclonal BHLHE41 Primary Antibody for IHC, IHC (p) - ABIN446884
Inaguma, Riku, Hashimoto, Murakami, Saga, Ikeda, Kasai: GLI1 interferes with the DNA mismatch repair system in pancreatic cancer through BHLHE41-mediated suppression of MLH1. in Cancer research 2013
Show all 2 references for ABIN446884
Human Monoclonal BHLHE41 Primary Antibody for IF, ELISA - ABIN528943
Lecomte, Meugnier, Euthine, Durand, Freyssenet, Nemoz, Rome, Vidal, Lefai: A new role for sterol regulatory element binding protein 1 transcription factors in the regulation of muscle mass and muscle cell differentiation. in Molecular and cellular biology 2010
the present study indicated that SHARP1 acts as a tumor suppressor in thyroid cancer and that its downregulation may contribute to the proliferation, migration and invasion of thyroid cancer cells through mechanisms possibly involving HIF1alpha (show HIF1A Antibodies)
Study found that DEC2 was a direct target of miR (show MLXIP Antibodies)-138.
DEC2 is aberrantly expressed in rheumatoid arthritis tissue, it is induced by TNFalpha (show TNF Antibodies) and not only affects the expression of genes belonging to molecular clock but also significantly impacts on the expression of IL-1beta (show IL1B Antibodies) as well as other inflammatory genes.
BHLHE40 (show BHLHE40 Antibodies)/41 are promising markers to predict the aggressiveness of each Endometrial Neoplasm case and that molecular targeting strategies involving BHLHE40 (show BHLHE40 Antibodies)/41 and SP1 (show PSG1 Antibodies) may effectively regulate Endometrial Neoplasm progression.
DEC2 facilitates HIF-1alpha (show HIF1A Antibodies) stabilization and promotes HIF-1 (show HIF1A Antibodies) activation in osteosarcoma.
DEC2 participates in hypoxia-induced cell proliferation by functioning as a target gene of the PI3K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies) signaling pathway and regulating the expression of c-Myc (show MYC Antibodies).
SHARP1 interacted with HIF-1alpha (show HIF1A Antibodies) physically.
Data suggest that SHARP1 plays a critical role in tumorigenesis and acquisition of the metastatic phenotype in endometrial cancer.
DEC2 regulates cellular function by modulating the expression of Twist1 (show TWIST1 Antibodies)
BHLHE41 mutations reduce total sleep while maintaining NREM sleep and provide resistance to the effects of sleep loss; mutations that affect sleep also modify the normal inhibition of BHLHE41 of CLOCK/BMAL1 (show ARNTL Antibodies) transactivation
Data show that the bHLH transcription factors SHARP1 and SHARP2 are involved in cognitive processing by controlling insulin-like growth factor II (Igf2) expression and associated signaling cascades.
abnormal sleep and certain (endo)phenotypes of psychiatric diseases may be caused by common mechanisms involving components of the molecular clock including SHARP1 and SHARP2 (show BHLHE40 Antibodies).
SENP1 (show SENP1 Antibodies) enhances adipogenesis through de-SUMOylation of Sharp-1, which then releases Sharp-1 repression of PPARgamma (show PPARG Antibodies) expression and adipocyte differentiation. These results reveal SENP1 (show SENP1 Antibodies) as a novel regulator in adipogenesis.
These results demonstrate that Sharp-1 regulates muscle regenerative capacity, at least in part, by modulation of TGF-beta (show TGFB1 Antibodies) signaling
Data show that G9a (show EHMT2 Antibodies), a lysine methyltransferase, is involved in Sharp-1-mediated inhibition of muscle differentiation.
Interactions of Per1 (show PER1 Antibodies)/2 and Dec2 in the regulation of period, phase, and rhythm sustainment are cell-type specific.
RORalpha suppresses adipogenic differentiation at a later stage of differentiation by RORE-mediated stimulation of Dec1 (show BHLHE40 Antibodies) and Dec2 expression.
Results suggest a partially redundant and bidirectional regulatory function for Dec1 (show BHLHE40 Antibodies)/2 genes in transcriptional translational feedback loops and conservation of Per1 (show PER1 Antibodies)-Dec (show PTEN Antibodies) synergism between vertebrate and invertebrate clocks.
measured circadian locomotor behavior and clock gene expression in the SCN (show SRI Antibodies) of Per2 (show PER2 Antibodies)/Dec1 (show BHLHE40 Antibodies)/2 double- and triple-mutant mice to analyze the functional interaction of PER2 (show PER2 Antibodies) and DEC1 (show BHLHE40 Antibodies)/2 feedback on circadian pacemaker function in the SCN (show SRI Antibodies)
This gene encodes a transcription factor that belongs to the Hairy/Enhancer of Split subfamily of basic helix-loop-helix factors. The encoded protein functions as a transcriptional repressor and as a regulator of molecular clock. Defects in this gene are associated with the short sleep phenotype.
basic helix-loop-helix domain containing, class B, 3
, basic helix-loop-helix family, member e41
, class E basic helix-loop-helix protein 41
, differentially expressed in chondrocytes protein 2
, enhancer-of-split and hairy-related protein 1
, bHLH transcriptional factor Dec2
, basic helix-loop-helix domain containing, class B3
, class B basic helix-loop-helix protein 3