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BATF3 encodes a member of the basic leucine zipper protein family. Additionally we are shipping BATF3 Proteins (9) and BATF3 Kits (1) and many more products for this protein.
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Human Polyclonal BATF3 Primary Antibody for WB - ABIN2781072
Bower, Fritz, McGuire: Transcriptional repression of MMP-1 by p21SNFT and reduced in vitro invasiveness of hepatocarcinoma cells. in Oncogene 2004
Batf3-dependent dendritic cells elicit the rejection of cells and grafts expressing mismatched minor histocompatibility antigens.
correlation of transcriptional repression by p21 (show CDKN1A Antibodies)(SNFT) with changes in DNA.NF-AT complex interactions
overexpression of p21SNFT in HepG2 cells leads to repression of matrix metalloproteinase-1 (show MMP1 Antibodies) by 70-80%
Batf3 deficiency is not critical for the generation of CD8alpha dendritic cells.
Data indicte that interferon regulatory factor 8 (IRF8 (show IRF8 Antibodies)) expression becomes dependent on transcription factor Batf3.
IL-12 (show IL12A Antibodies) production by Batf3-dependent CD103 (show ITGAE Antibodies)+ dendritic cells is crucial for maintenance of local Th1 (show HAND1 Antibodies) immunity against L. major infection.
The basic leucine zipper ATF-like 3 (BATF3)- dendritic cell lineage is enriched in the lungs of asthma-protected mice and strictly required for protection.
Irf8 expression in DC9 cells led to an increase in Batf3 transcript levels.When coexpressed with Irf8, Batf3 & Id2 had a synergistic effect on classical CD8alpha(+) DC development.
Batf3-dependent DCs in the renal lymph node presented antigen that had been concentrated in the kidney and used PD-L1 (show CD274 Antibodies) to induce apoptosis of cytotoxic T cells
A previously undescribed pathway by which CD8alpha+ Dendritic cells emerge independent of Id2, Nfil3 (show NFIL3 Antibodies), and Batf3, but dependent on Irf8 (show IRF8 Antibodies).
Data show that targeting of antigen to Clec9A (show CLEC9A Antibodies) in batf3 null mice produced enhanced antibody responses.
Defective T effector priming and resistance to experimental autoimmune encephalitis (EAE) exhibited by Csf2rb (show CSF2RB Antibodies)(-/-) mice does not result from the absence of dermal CD11b (show ITGAM Antibodies)(low/-)Langerin (show CD207 Antibodies)(+)CD103 (show ITGAE Antibodies)(+) dendritic cells.
study describes a transcription factor, Batf3, that controls development of CD8 (show CD8A Antibodies)+ dendritic cells; dendritic cells from Batf3-/- mice were defective in cross-presentation, and Batf3-/- mice lacked virus-specific CD8 (show CD8A Antibodies)+ T cell responses to West Nile virus
This gene encodes a member of the basic leucine zipper protein family. The encoded protein functions as a transcriptional repressor when heterodimerizing with JUN. The protein may play a role in repression of interleukin-2 and matrix metalloproteinase-1 transcription.
basic leucine zipper transcription factor, ATF-like 3
, basic leucine zipper transcriptional factor ATF-like 3
, Basic leucine zipper transcriptional factor ATF-like 3
, 21 kDa small nuclear factor isolated from T-cells
, 21-kD small nuclear factor isolated from T cells
, Jun dimerization protein 1
, Jun dimerization protein p21SNFT