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BATF3 encodes a member of the basic leucine zipper protein family. Additionally we are shipping BATF3 Proteins (9) and BATF3 Kits (1) and many more products for this protein.
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Basic Leucine Zipper ATF-Like Transcription Factor 3 (show TCF3 Antibodies) (BATF3), an AP-1 (show FOSB Antibodies) family transcription factor, is a glucocorticoid receptor (show NR3C1 Antibodies) coregulator whose interaction with glucocorticoid receptor (show NR3C1 Antibodies) is modulated by the lever arm.
Batf3-dependent dendritic cells elicit the rejection of cells and grafts expressing mismatched minor histocompatibility antigens.
correlation of transcriptional repression by p21 (show CDKN1A Antibodies)(SNFT) with changes in DNA.NF-AT complex interactions
overexpression of p21SNFT in HepG2 cells leads to repression of matrix metalloproteinase-1 (show MMP1 Antibodies) by 70-80%
Batf3(-/-) mice remained competent for skin graft rejection and delayed hypersensitivity, and retained a CD8 (show CD8A Antibodies)(+) dendritic cell population.
Lack of Batf3/CD103 (show ITGAE Antibodies)(+) dendritic cells within the tumor microenvironment dominantly resists the effector phase of an anti-tumor T cell response, contributing to immune escape.
study reports that Batf3 is critical for accumulation of CD103 (show ITGAE Antibodies)(+) DCs in the kidney and tongue at steady state, for their expansion during systemic and oropharyngeal candidiasis, and for tissue-specific production of IL-12 (show IL12A Antibodies) in kidney but not tongue during systemic and oropharyngeal candidiasis, respectively
this study shows that Batf3 promotes priming of CD8 (show CD8A Antibodies)+ T cells regardless of the location of Salmonella enterica antigen
Batf3 deficiency is not critical for the generation of CD8alpha dendritic cells.
Data indicte that interferon regulatory factor 8 (IRF8 (show IRF8 Antibodies)) expression becomes dependent on transcription factor Batf3.
IL-12 (show IL12A Antibodies) production by Batf3-dependent CD103 (show ITGAE Antibodies)+ dendritic cells is crucial for maintenance of local Th1 (show HAND1 Antibodies) immunity against L. major infection.
The basic leucine zipper ATF-like 3 (BATF3)- dendritic cell lineage is enriched in the lungs of asthma-protected mice and strictly required for protection.
Irf8 expression in DC9 cells led to an increase in Batf3 transcript levels.When coexpressed with Irf8, Batf3 & Id2 had a synergistic effect on classical CD8alpha(+) DC development.
Batf3-dependent DCs in the renal lymph node presented antigen that had been concentrated in the kidney and used PD-L1 (show CD274 Antibodies) to induce apoptosis of cytotoxic T cells
This gene encodes a member of the basic leucine zipper protein family. The encoded protein functions as a transcriptional repressor when heterodimerizing with JUN. The protein may play a role in repression of interleukin-2 and matrix metalloproteinase-1 transcription.
basic leucine zipper transcription factor, ATF-like 3
, basic leucine zipper transcriptional factor ATF-like 3
, Basic leucine zipper transcriptional factor ATF-like 3
, 21 kDa small nuclear factor isolated from T-cells
, 21-kD small nuclear factor isolated from T cells
, Jun dimerization protein 1
, Jun dimerization protein p21SNFT