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BTF3 encodes the basic transcription factor 3. Additionally we are shipping BTF3 Proteins (7) and BTF3 Kits (2) and many more products for this protein.
Showing 10 out of 74 products:
Cow (Bovine) Polyclonal BTF3 Primary Antibody for WB - ABIN2780354
Freire: Translation initiation factor (iso) 4E interacts with BTF3, the beta subunit of the nascent polypeptide-associated complex. in Gene 2005
Show all 2 Pubmed References
BTF3, HINT1 (show HINT1 Antibodies), NDRG1 (show NDRG1 Antibodies) and ODC1 (show ODC1 Antibodies) protein over-expression in human prostate cancer tissue
BTF3 expression is associated with enhanced cell proliferation, reduced cell cycle regulation and apoptosis and its silencing decreased colony forming and proliferation of gastric cancer cells.
BTF3 overexpression may be an early event in colorectal cancer development and could be useful biomarker for the early stage of colorectal cancers (CRC (show CALR Antibodies)); BTF3 has positive correlations with NF-kappaB (show NFKB1 Antibodies), RAD50 (show RAD50 Antibodies), MRE11 (show MRE11A Antibodies), NBS1 (show NBN Antibodies) and AEG-1 (show MTDH Antibodies) and might influence complex signal pathways in CRC (show CALR Antibodies)
BTF3 is overexpressed in pancreatic ductal adenocarcinoma , where it acts as a transcriptional regulator rather than a direct modulator of apoptosis.
BTF3 interacts with ERalpha (show ESR1 Antibodies) that has been activated either by 17beta-estradiol (ligand-dependent activation) or by epidermal growth factor (show EGF Antibodies) (ligand-independent activation).
In addition to RNA polymerase II (otherwise RNA pol II, RNA polymerase B), four general transcription factors are required for initiation of transcription: BTF1 (show BTN2A1 Antibodies) (also referred to as TFIID (show TBP Antibodies)) which has recently been cloned from yeast, BTF2 (show GTF2H1 Antibodies), BTF3 and STF.
Six putative caspase (show CASP3 Antibodies) substrates, including five novel proteins (ABCF1 (show ABCF1 Antibodies), AKAP1 (show AKAP1 Antibodies), CPE (show CPE Antibodies), DOPEY1 (show DOPEY1 Antibodies) and GOPC1 (show GOPC Antibodies)) that may be targeted specifically by the initiator caspases 8 and 10 during the early stages of apoptosis, were identified.[caspase 10 (show CASP10 Antibodies)]
This gene encodes the basic transcription factor 3. This protein forms a stable complex with RNA polymerase IIB and is required for transcriptional initiation. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene has multiple pseudogenes.
basic transcription factor 3
, transcription factor BTF3
, RNA polymerase B transcription factor 3
, nascent-polypeptide-associated complex beta polypeptide