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The protein encoded by BSG is a plasma membrane protein that is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. Additionally we are shipping CD147 Kits (49) and CD147 Proteins (34) and many more products for this protein.
Showing 10 out of 567 products:
Human Monoclonal CD147 Primary Antibody for FACS, IHC (p) - ABIN238486
Xu, Hemler: Metabolic activation-related CD147-CD98 complex. in Molecular & cellular proteomics : MCP 2005
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Human Monoclonal CD147 Primary Antibody for FACS, IHC (p) - ABIN119255
Koch, Staffler, Hüttinger, Hilgert, Prager, Cerný, Steinlein, Majdic, Horejsí, Stockinger: T cell activation-associated epitopes of CD147 in regulation of the T cell response, and their definition by antibody affinity and antigen density. in International immunology 1999
Show all 7 references for ABIN119255
Mouse (Murine) Monoclonal CD147 Primary Antibody for FACS - ABIN119970
Moretta, Tambussi, Bottino, Tripodi, Merli, Ciccone, Pantaleo, Moretta: A novel surface antigen expressed by a subset of human CD3- CD16+ natural killer cells. Role in cell activation and regulation of cytolytic function. in The Journal of experimental medicine 1990
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Human Monoclonal CD147 Primary Antibody for FACS, IF - ABIN119254
Hu, Dang, Yao, Li, Zhang, Yang, Xu, Bian, Xing, Zhu, Chen: Involvement of HAb18G/CD147 in T cell activation and immunological synapse formation. in Journal of cellular and molecular medicine 2010
Show all 6 references for ABIN119254
Mouse (Murine) Monoclonal CD147 Primary Antibody for FACS, IHC (fro) - ABIN119971
Hanna, Kirk, Holt, Puklavec, Brown, Barclay: A novel form of the membrane protein CD147 that contains an extra Ig-like domain and interacts homophilically. in BMC biochemistry 2004
Show all 2 references for ABIN119971
Data suggest that EMMPRIN derived from endometrial epithelial cells regulates expression of matrix metalloproteinases (MMP-2 (show MMP2 Antibodies); MMP-14 (show MMP14 Antibodies)) in endometrial stromal cells; progesterone-rich conditions stimulate expression of EMMPRIN in endometrium.
The selective S-nitrosylation of EMMPRIN and GOLPH3 (show GOLPH3 Antibodies) at the Golgi apparatus in endothelial cells results from the physical proximity to eNOS (show NOS3 Antibodies)-derived nitric oxide.
EMMPRIN from the luminal epithelium may regulate the expression of stromal MMP-2 (show MMP2 Antibodies) and MMP-14 (show MMP14 Antibodies) suggesting a role in adhesion and fusion of embryo to luminal epithelium.
knockdown of CD147 on Hepa1-6 cells resulted in significantly increased T cells chemotaxis induced by CypA (show PPIA Antibodies) both in vivo and in vitro.
These findings indicate that TGF-beta1 (show TGFB1 Antibodies)-CD147 loop plays a key role in regulating the HSC (show FUT1 Antibodies) activation and combination of TGF-beta (show TGFB1 Antibodies) receptor inhibitor and anti-CD147 antibody might be promised to reverse fibrogenesis.
Decreased CD147 expression inhibited osteoclast formation and bone resorption, inhibited RANKL (show TNFSF11 Antibodies)-induced nuclear translocation of the nuclear factor of activated T cells NFATc1 (show NFATC1 Antibodies).
EMMPRIN promotes tumor growth and metastasis by recruitment of bone marrow-derived cells through controlling secretion and paracrine signaling of SDF-1 and VEGF.
Results indicate the crucial roles of intracellular and extracellular Bsg in the pathogenesis of cardiac hypertrophy, fibrosis, and failure.
Disruption of BASIGIN in tumour cells and in MEFs has no action on the production of MMPs.
Extracellular CyPA (show PPIA Antibodies) activates platelets via cluster of differentiation 147-mediated phosphoinositid-3-kinase/Akt (show AKT1 Antibodies)-signaling, leading to enhanced adhesion and thrombus formation independently of intracellular CyPA (show PPIA Antibodies)
Bsg plays an indispensable role in Th17 cell differentiation as a negative regulator by suppressing the IL-6 (show IL6 Antibodies)/STAT-3 (show STAT3 Antibodies) pathway.
may promote liver fibrosis progression via inducing the VEGF-A (show VEGFA Antibodies)/VEGFR-2 (show KDR Antibodies) signalling pathway-mediated cross-talk between hepatocytes and sinusoidal endothelial cells
our results demonstrated that CD147 was upregulated in the liver parenchymal and mesenchymal cells and involved in angiogenesis and tumor cell proliferation in the development of DEN/PB-induced HCC (show FAM126A Antibodies).
Basigin is important in vision, spermatogenesis and other physiological phenomena, and plays significant roles in the pathogenesis of numerous diseases, including cancer. Basigin is also the receptor for an invasive protein RH5 (show RHO Antibodies), which is present in malaria parasites.
The present study indicated that Slug (show SNAI2 Antibodies) and EMMPRIN are potential biomarkers and therapeutic targets for the diagnosis and treatment of perineural invasion in human salivary adenoid cystic carcinoma.
CD147 promoted the differentiation of Th17 cells by regulation of cytokine production, which provided the evidence for pathogenesis and potential therapeutic targets for rheumatoid arthritis.
Study identified CD147 as a novel interaction partner for E2F1 (show E2F1 Antibodies) and suggest a role in promoting tumor cell invasion and migration of prostate cancer cells.
High BSG expression is associated with melanoma invasion and metastasis.
High CD147 promotes liver tumor cell movement and metastasis via direct interaction with Annexin A2 (show ANXA2 Antibodies) and DOCK3 (show DOCK3 Antibodies)-beta-catenin (show CTNNB1 Antibodies)-WAVE2 (show WASF2 Antibodies) signaling axis.
High CD147 expression was significantly associated with tumorigenicity of Kaposi's sarcoma-associated herpesvirus infected endothelial cells.
CD147 also participates in inflammation, nutrient and drug transporter activity, microbial pathology and developmental processes
CD147 is resistant to tumor necrosis factor (show TNF Antibodies)-induced apoptosis by promoting IKK (show CHUK Antibodies)/IkappaB/NF-kappaB (show NFKB1 Antibodies) pathway, and the extracellular portion of CD147 is the functional region.
MCT1 (show CMA1 Antibodies) expression was not clearly associated with overall or disease-free survival. MCT4 (show SLC16A4 Antibodies) and CD147 expression correlate with worse prognosis across many cancer types. These results warrant further investigation of these associations
CD147 is required for the expression of MCT1 (show MCTS1 Antibodies) and MCT4 (show SLC16A3 Antibodies) in the corneal endothelium. Silencing CD147 slows lactate efflux, resulting in stromal lactate accumulation and corneal edema.
The protein encoded by this gene is a plasma membrane protein that is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. The encoded protein is also a member of the immunoglobulin superfamily. Multiple transcript variants encoding different isoforms have been found for this gene.
, HT7 antigen
, basic immunoglobulin superfamily
, gp 42
, membrane glycoprotein gp42
, CD147 antigen
, OK blood group antigen
, collagenase stimulatory factor
, extracellular matrix metalloproteinase inducer
, leukocyte activation antigen M6
, tumor cell-derived collagenase stimulatory factor
, Basigin (Ox47 antigen or CE-9) (EMMPRIN in human) (neurothelin HT7 or 5A11 in avian)
, Basignin (Ox47 antigen or CE-9) (EMMPRIN in human) (neurothelin HT7 or 5A11 in avian)
, OX-47 antigen
, glycoprotein CE9
, 5A11 antigen
, blood-brain barrier HT7 antigen