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The protein encoded by BSG is a plasma membrane protein that is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. Additionally we are shipping CD147 Kits (65) and CD147 Proteins (32) and many more products for this protein.
Showing 10 out of 570 products:
Human Monoclonal CD147 Primary Antibody for FACS, IHC (p) - ABIN238486
Xu, Hemler: Metabolic activation-related CD147-CD98 complex. in Molecular & cellular proteomics : MCP 2005
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Human Monoclonal CD147 Primary Antibody for FACS, IHC (p) - ABIN119255
Koch, Staffler, Hüttinger, Hilgert, Prager, Cerný, Steinlein, Majdic, Horejsí, Stockinger: T cell activation-associated epitopes of CD147 in regulation of the T cell response, and their definition by antibody affinity and antigen density. in International immunology 1999
Show all 7 references for ABIN119255
Human Monoclonal CD147 Primary Antibody for Func, FACS - ABIN638433
Melchior, Denys, Deligny, Mazurier, Allain: Cyclophilin B induces integrin-mediated cell adhesion by a mechanism involving CD98-dependent activation of protein kinase C-delta and p44/42 mitogen-activated protein kinases. in Experimental cell research 2008
Show all 6 references for ABIN638433
Human Monoclonal CD147 Primary Antibody for FACS, IF - ABIN119254
Hu, Dang, Yao, Li, Zhang, Yang, Xu, Bian, Xing, Zhu, Chen: Involvement of HAb18G/CD147 in T cell activation and immunological synapse formation. in Journal of cellular and molecular medicine 2010
Show all 6 references for ABIN119254
Mouse (Murine) Monoclonal CD147 Primary Antibody for FACS - ABIN119970
Moretta, Tambussi, Bottino, Tripodi, Merli, Ciccone, Pantaleo, Moretta: A novel surface antigen expressed by a subset of human CD3- CD16+ natural killer cells. Role in cell activation and regulation of cytolytic function. in The Journal of experimental medicine 1990
Show all 6 references for ABIN119970
Mouse (Murine) Monoclonal CD147 Primary Antibody for FACS, IHC (fro) - ABIN119971
Hanna, Kirk, Holt, Puklavec, Brown, Barclay: A novel form of the membrane protein CD147 that contains an extra Ig-like domain and interacts homophilically. in BMC biochemistry 2004
Show all 2 references for ABIN119971
Data suggest that EMMPRIN derived from endometrial epithelial cells regulates expression of matrix metalloproteinases (MMP-2 (show MMP2 Antibodies); MMP-14 (show MMP14 Antibodies)) in endometrial stromal cells; progesterone-rich conditions stimulate expression of EMMPRIN in endometrium.
The selective S-nitrosylation of EMMPRIN and GOLPH3 (show GOLPH3 Antibodies) at the Golgi apparatus in endothelial cells results from the physical proximity to eNOS (show NOS3 Antibodies)-derived nitric oxide.
EMMPRIN from the luminal epithelium may regulate the expression of stromal MMP-2 (show MMP2 Antibodies) and MMP-14 (show MMP14 Antibodies) suggesting a role in adhesion and fusion of embryo to luminal epithelium.
These findings indicate that TGF-beta1 (show TGFB1 Antibodies)-CD147 loop plays a key role in regulating the HSC (show FUT1 Antibodies) activation and combination of TGF-beta (show TGFB1 Antibodies) receptor inhibitor and anti-CD147 antibody might be promised to reverse fibrogenesis.
Decreased CD147 expression inhibited osteoclast formation and bone resorption, inhibited RANKL (show TNFSF11 Antibodies)-induced nuclear translocation of the nuclear factor of activated T cells NFATc1 (show NFATC1 Antibodies).
EMMPRIN promotes tumor growth and metastasis by recruitment of bone marrow-derived cells through controlling secretion and paracrine signaling of SDF-1 and VEGF.
Results indicate the crucial roles of intracellular and extracellular Bsg in the pathogenesis of cardiac hypertrophy, fibrosis, and failure.
Disruption of BASIGIN in tumour cells and in MEFs has no action on the production of MMPs.
Extracellular CyPA (show PPIA Antibodies) activates platelets via cluster of differentiation 147-mediated phosphoinositid-3-kinase/Akt (show AKT1 Antibodies)-signaling, leading to enhanced adhesion and thrombus formation independently of intracellular CyPA (show PPIA Antibodies)
Bsg plays an indispensable role in Th17 cell differentiation as a negative regulator by suppressing the IL-6 (show IL6 Antibodies)/STAT-3 (show STAT3 Antibodies) pathway.
may promote liver fibrosis progression via inducing the VEGF-A (show VEGFA Antibodies)/VEGFR-2 (show KDR Antibodies) signalling pathway-mediated cross-talk between hepatocytes and sinusoidal endothelial cells
our results demonstrated that CD147 was upregulated in the liver parenchymal and mesenchymal cells and involved in angiogenesis and tumor cell proliferation in the development of DEN/PB-induced HCC (show FAM126A Antibodies).
EMMPRIN ensures proper actomyosin-driven maturation of competent endothelial junctions by forming a molecular complex with gamma-catenin (also known as junction plakoglobin) and Nm23 (also known as NME1), a nucleoside diphosphate kinase
CD147 also participates in inflammation, nutrient and drug transporter activity, microbial pathology and developmental processes
CD147 is resistant to tumor necrosis factor (show TNF Antibodies)-induced apoptosis by promoting IKK (show CHUK Antibodies)/IkappaB/NF-kappaB (show NFKB1 Antibodies) pathway, and the extracellular portion of CD147 is the functional region.
MCT1 (show CMA1 Antibodies) expression was not clearly associated with overall or disease-free survival. MCT4 (show SLC16A4 Antibodies) and CD147 expression correlate with worse prognosis across many cancer types. These results warrant further investigation of these associations
CD147 is increased in hepatocellular carcinoma cells under starvation and reduces cell death through upregulating mTOR (show FRAP1 Antibodies) in vitro.
EMMPRIN, MMP8 (show MMP8 Antibodies), hyaluronan, beta-defensing-2, and neutrophil gelatinase-associated lipocalin (NGAL (show LCN2 Antibodies)) are elevated in women with vaginal inflammation
High CD147 expression is associated with multiple myeloma.
role of CD147 in the regulation of lipid metabolism, including de novo lipogenesis and fatty acid beta-oxidation, in hepatocellular carcinoma cells
both EGFR (show EGFR Antibodies) and EMMPRIN proteins are potential targets for cancer therapy and EMMPRIN can be used as a prognostic marker of a more aggressive biological behavior in patients with head and neck squamous cell carcinoma
The cHAb18 was produced in rNDV-18HL-infected cells followed by releasing into the supernatant by cytolysis. The rNDV-18HL-encoded cHAb18 antibody kept affinity for CD147 and showed inhibiting the migration and invasion of hepatocellular carcinoma cells
these results reveal that CD147 functions as a critical regulator of endoplasmic reticulum -dependent [Ca2 (show CA2 Antibodies)+]i oscillations to promote oncogenic progression in hepatocellular carcinoma
CD147 is required for the expression of MCT1 (show MCTS1 Antibodies) and MCT4 (show SLC16A3 Antibodies) in the corneal endothelium. Silencing CD147 slows lactate efflux, resulting in stromal lactate accumulation and corneal edema.
The protein encoded by this gene is a plasma membrane protein that is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. The encoded protein is also a member of the immunoglobulin superfamily. Multiple transcript variants encoding different isoforms have been found for this gene.
, HT7 antigen
, basic immunoglobulin superfamily
, gp 42
, membrane glycoprotein gp42
, CD147 antigen
, OK blood group antigen
, collagenase stimulatory factor
, extracellular matrix metalloproteinase inducer
, leukocyte activation antigen M6
, tumor cell-derived collagenase stimulatory factor
, Basigin (Ox47 antigen or CE-9) (EMMPRIN in human) (neurothelin HT7 or 5A11 in avian)
, Basignin (Ox47 antigen or CE-9) (EMMPRIN in human) (neurothelin HT7 or 5A11 in avian)
, OX-47 antigen
, glycoprotein CE9
, 5A11 antigen
, blood-brain barrier HT7 antigen