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Basigin (Ok Blood Group) Proteins (BSG)

The protein encoded by BSG is a plasma membrane protein that is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. Additionally we are shipping CD147 Antibodies (583) and CD147 Kits (51) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
BSG 12215 P18572
BSG 682 P35613
BSG 25246 P26453
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Top CD147 Proteins at antibodies-online.com

Showing 10 out of 36 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_HEK-293 Cells Human His tag Human EMMPRIN, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%. 100 μg Log in to see 2 to 3 Days
$286.00
Details
HOST_Human Cells Human Fc Tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Human Cells Human Un-conjugated 50 μg Log in to see 16 Days
$272.80
Details
HOST_Human Cells Mouse His tag 100 μg Log in to see 16 Days
$382.80
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_HEK-293 Cells Human His tag 50 μg Log in to see 2 to 3 Days
$651.00
Details
HOST_Escherichia coli (E. coli) Human His tag Basigin (Ok Blood Group) (BSG) (AA 138-321), (partial) protein (His tag) 50 μg Log in to see 9 to 11 Days
$242.00
Details

BSG Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) , , ,
, , ,
Human , , , , , , , ,
, , , ,
Rat (Rattus)

Top referenced CD147 Proteins

  1. Human CD147 Protein expressed in Human Cells - ABIN2002283 : Hakuma, Betsuyaku, Kinoshita, Itoh, Kaga, Kondo, Nishimura, Dosaka-Akita: High incidence of extracellular matrix metalloproteinase inducer expression in non-small cell lung cancers. Association with clinicopathological parameters. in Oncology 2008 (PubMed)
    Show all 5 references for ABIN2002283

  2. Mouse (Murine) CD147 Protein expressed in Human Cells - ABIN2007682 : Kanekura, Miyauchi, Tashiro, Muramatsu et al.: Basigin, a new member of the immunoglobulin superfamily: genes in different mammalian species, glycosylation changes in the molecule from adult organs and possible variation in the N-terminal ... in Cell structure and function 1991 (PubMed)
    Show all 5 references for ABIN2007682

  3. Human CD147 Protein expressed in Human Cells - ABIN2002278 : Muramatsu, Miyauchi: Basigin (CD147): a multifunctional transmembrane protein involved in reproduction, neural function, inflammation and tumor invasion. in Histology and histopathology 2003 (PubMed)
    Show all 5 references for ABIN2002278

  4. Human CD147 Protein expressed in HEK-293 Cells - ABIN2180696 : Kasinrerk, Fiebiger, Stefanová, Baumruker, Knapp, Stockinger: Human leukocyte activation antigen M6, a member of the Ig superfamily, is the species homologue of rat OX-47, mouse basigin, and chicken HT7 molecule. in Journal of immunology (Baltimore, Md. : 1950) 1992 (PubMed)
    Show all 2 references for ABIN2180696

More Proteins for Basigin (Ok Blood Group) (BSG) Interaction Partners

Cow (Bovine) Basigin (Ok Blood Group) (BSG) interaction partners

  1. Data suggest that EMMPRIN derived from endometrial epithelial cells regulates expression of matrix metalloproteinases (MMP-2 (show MMP2 Proteins); MMP-14 (show MMP14 Proteins)) in endometrial stromal cells; progesterone-rich conditions stimulate expression of EMMPRIN in endometrium.

  2. The selective S-nitrosylation of EMMPRIN and GOLPH3 (show GOLPH3 Proteins) at the Golgi apparatus in endothelial cells results from the physical proximity to eNOS (show NOS3 Proteins)-derived nitric oxide.

  3. EMMPRIN from the luminal epithelium may regulate the expression of stromal MMP-2 (show MMP2 Proteins) and MMP-14 (show MMP14 Proteins) suggesting a role in adhesion and fusion of embryo to luminal epithelium.

Mouse (Murine) Basigin (Ok Blood Group) (BSG) interaction partners

  1. These results suggest that basigin has a functional role as a binding partner with MCT2 in testicular and epididymal spermatozoa.

  2. both caveolin-1 (show CAV1 Proteins) and EMMPRIN mRNA levels increased gradually with progression of developmental stages, and peaked at day two postnatal. The current finding suggests that both caveolin-1 (show CAV1 Proteins) and EMMPRIN take part in mouse tooth development, especially in the differentiation and organization of odontogenic tissues.

  3. knockdown of CD147 on Hepa1-6 cells resulted in significantly increased T cells chemotaxis induced by CypA (show PPIA Proteins) both in vivo and in vitro.

  4. These findings indicate that TGF-beta1 (show TGFB1 Proteins)-CD147 loop plays a key role in regulating the HSC (show FUT1 Proteins) activation and combination of TGF-beta (show TGFB1 Proteins) receptor inhibitor and anti-CD147 antibody might be promised to reverse fibrogenesis.

  5. Decreased CD147 expression inhibited osteoclast formation and bone resorption, inhibited RANKL (show TNFSF11 Proteins)-induced nuclear translocation of the nuclear factor of activated T cells NFATc1 (show NFATC1 Proteins).

  6. EMMPRIN promotes tumor growth and metastasis by recruitment of bone marrow-derived cells through controlling secretion and paracrine signaling of SDF-1 and VEGF.

  7. Results indicate the crucial roles of intracellular and extracellular Bsg in the pathogenesis of cardiac hypertrophy, fibrosis, and failure.

  8. Disruption of BASIGIN in tumour cells and in MEFs has no action on the production of MMPs.

  9. Extracellular CyPA (show PPIA Proteins) activates platelets via cluster of differentiation 147-mediated phosphoinositid-3-kinase/Akt (show AKT1 Proteins)-signaling, leading to enhanced adhesion and thrombus formation independently of intracellular CyPA (show PPIA Proteins)

  10. Bsg plays an indispensable role in Th17 cell differentiation as a negative regulator by suppressing the IL-6 (show IL6 Proteins)/STAT-3 (show STAT3 Proteins) pathway.

Human Basigin (Ok Blood Group) (BSG) interaction partners

  1. This study identified that combination of nadroparin and irradiation had a strong synergistic antitumor effect in a dose- and time-related manner in vitro, which was reflected in the inhibition of cell viability, invasion and metastasis, promotion of apoptosis, inhibited secretion level of TGF-beta1 (show TGFB1 Proteins) and downregulation of CD147, MMP-2 (show MMP2 Proteins) and survivin (show BIRC5 Proteins) expression.

  2. in cultured H9C2 cells and that CyPA (show PPIA Proteins)/CD147 signaling pathway inhibition protects against Ang II (show AGT Proteins)-induced cardiomyocyte hypertrophy.

  3. CD147 was significantly upregulated in the human glioma cell lines. Downregulation of CD147 suppressed cell proliferation, blocked cell cycle, induced apoptosis, inhibited cell invasion and angiogenesis in glioma cells in vitro. CD147 was significantly associated with WHO tumor grade and angiogenesis; silencing of CD147 contributed to inhibition of glioma proliferation, invasion and angiogenesis.

  4. rs11473 polymorphism at the miR (show MLXIP Proteins)- 483-5p binding site in the 3'-UTR of basigin gene may play a key role in the development of esophageal cancer in a Chinese population.

  5. findings of this research defined a novel relationship between the down-regulation of miR (show MLXIP Proteins)-22 and the up-regulation of CD147 and demonstrated that CD147 is a downstream factor of miR (show MLXIP Proteins)-22.

  6. Triptolide represses the migration and invasion of prostate cancer cells through Cav-1 (show CAV1 Proteins)/CD147/MMPs signalling pathway.

  7. Basigin is important in vision, spermatogenesis and other physiological phenomena, and plays significant roles in the pathogenesis of numerous diseases, including cancer. Basigin is also the receptor for an invasive protein RH5, which is present in malaria parasites.

  8. The present study indicated that Slug (show SNAI2 Proteins) and EMMPRIN are potential biomarkers and therapeutic targets for the diagnosis and treatment of perineural invasion in human salivary adenoid cystic carcinoma.

  9. CD147 promoted the differentiation of Th17 cells by regulation of cytokine production, which provided the evidence for pathogenesis and potential therapeutic targets for rheumatoid arthritis.

  10. Study identified CD147 as a novel interaction partner for E2F1 (show E2F1 Proteins) and suggest a role in promoting tumor cell invasion and migration of prostate cancer cells.

Rabbit Basigin (Ok Blood Group) (BSG) interaction partners

  1. CD147 is required for the expression of MCT1 (show MCTS1 Proteins) and MCT4 (show SLC16A3 Proteins) in the corneal endothelium. Silencing CD147 slows lactate efflux, resulting in stromal lactate accumulation and corneal edema.

CD147 (BSG) Protein Profile

Protein Summary

The protein encoded by this gene is a plasma membrane protein that is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. The encoded protein is also a member of the immunoglobulin superfamily. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with Basigin (Ok Blood Group) Proteins (BSG)

  • basigin (BSG)
  • basigin (Bsg)
  • basigin (Ok blood group) (BSG)
  • basigin (Ok blood group) (Bsg)
  • 5A11 protein
  • 5F7 protein
  • AI115436 protein
  • AI325119 protein
  • basignin protein
  • BSG protein
  • CD147 protein
  • CE9 protein
  • EMMPRIN protein
  • HT-7 protein
  • HT7 protein
  • M6 protein
  • OK protein
  • Ox47R protein
  • RPE7 protein
  • TCSF protein

Protein level used designations for Basigin (Ok Blood Group) Proteins (BSG)

basigin , 5A11/Basigin , HT7 antigen , basic immunoglobulin superfamily , gp 42 , membrane glycoprotein gp42 , neurothelin , CD147 antigen , OK blood group antigen , collagenase stimulatory factor , extracellular matrix metalloproteinase inducer , leukocyte activation antigen M6 , tumor cell-derived collagenase stimulatory factor , Basigin (Ox47 antigen or CE-9) (EMMPRIN in human) (neurothelin HT7 or 5A11 in avian) , Basignin (Ox47 antigen or CE-9) (EMMPRIN in human) (neurothelin HT7 or 5A11 in avian) , OX-47 antigen , glycoprotein CE9 , 5A11 antigen , blood-brain barrier HT7 antigen , gp42/basigin/OX-47/HT7

GENE ID SPECIES
347698 Bos taurus
12215 Mus musculus
682 Homo sapiens
100141312 Sus scrofa
476758 Canis lupus familiaris
25246 Rattus norvegicus
508716 Bos taurus
770363 Gallus gallus
100009229 Oryctolagus cuniculus
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