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The protein encoded by BMF belongs to the BCL2 protein family. Additionally we are shipping BMF Kits (23) and BMF Proteins (15) and many more products for this protein.
Showing 10 out of 118 products:
Human Polyclonal BMF Primary Antibody for EIA, IF - ABIN499481
Puthalakath, Villunger, OReilly, Beaumont, Coultas, Cheney, Huang, Strasser: Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis. in Science (New York, N.Y.) 2001
Show all 2 references for ABIN499481
Human Polyclonal BMF Primary Antibody for EIA, IHC (p) - ABIN499479
Hunt, Evan: Apoptosis. Till death us do part. in Science (New York, N.Y.) 2001
Show all 2 references for ABIN499479
Human Polyclonal BMF Primary Antibody for IHC, WB - ABIN411435
Chen, Huang, Wang: Deficiency of Bim in dendritic cells contributes to overactivation of lymphocytes and autoimmunity. in Blood 2007
Show all 2 references for ABIN411435
these findings suggest that p53 (show TP53 Antibodies)-R273H can specifically drive AKT (show AKT1 Antibodies) signaling and suppress BMF expression, resulting in enhanced cell survivability and anoikis resistance.
On the corresponding BMF gene promoter, loss of HDAC8 (show HDAC8 Antibodies) was associated with signal transducer and activator of transcription 3 (STAT3 (show STAT3 Antibodies))/specificity protein 3 (Sp3) transcription factor exchange and recruitment of p300 (show EP300 Antibodies).
Overexpression of ApoL2 (show APOL2 Antibodies) did not induce cell death on its own. ApoL2 (show APOL2 Antibodies) did not sensitize or protect cells from overexpression of the BH3-only (show BBC3 Antibodies) proteins Bmf or Noxa (show PMAIP1 Antibodies).
Diva (show BCL2L10 Antibodies) binds peptides derived from the BH3 domain of several other proapoptotic Bcl-2 (show BCL2 Antibodies) proteins, including mouse Harakiri (show HRK Antibodies), Bid (show BID Antibodies), Bak (show BAK1 Antibodies) and Bmf.
BMF is induced in human IEC by the loss of cell attachment and is likely to play an important role in the regulation of IEC survival
characterization of the bmf gene locus; molecular basis of the generation of the 2 major isoforms of Bmf; provide evidence that Bmf can act as a sensor for stress that associates with the repression of the conventional CAP-dependent translation machinery
Data show that hypoxic conditions inhibit anoikis and block expression of proapoptotic BH3-only (show BBC3 Antibodies) family members Bim (show BCL2L11 Antibodies) and Bmf in epithelial cells.
Bmf is upregulated by PS-341 and has a crucial role in PS-341-mediated glioma cell death through JNK (show MAPK8 Antibodies) phosphorylation.
Up or downregulation of Bmf isoforms may have a role in regulating growth and survival in B cells and leukemic B-CLL cells
There was no somatic mutation of BH3 domains of Bad, Bmf and Bcl-G genes in transitional cell carcinoma samples. The data presented here indicate that BH3 domain mutation of these genes is rare in TCCs and may not contribute to the pathogenesis of TCCs.
BMF loss is associated with germ cell loss during oogenesis.
Bcl2 interacting mediator of cell death (Bim (show BCL2L11 Antibodies)) and Bcl2 modifying factor (Bmf), mediate apoptosis in the context of TACI (show TNFRSF13B Antibodies)-Ig overexpression that effectively neutralizes BAFF (show TNFSF13B Antibodies) as well as APRIL.
Bmf deficiency induced significant protection against oxygen/glucose deprivation injury in cultured neurons.
Our findings support an important role for BMF in determining the number of primordial follicles maintained in the ovary throughout adult reproductive life.
Bim (show BCL2L11 Antibodies) and Bmf act in concert to prevent autoimmunity and malignant disease
Bmf-deficient mice showed normal sensitivity to the convulsant effects of KA, displayed significantly more neuronal death in the hippocampal CA1 (show CA1 Antibodies) and CA3 (show CA3 Antibodies) subfields after SE.
deacetylation of p53 (show TP53 Antibodies) suppresses Bmf expression and facilitates autophagy.
critical role for Bim (show BCL2L11 Antibodies) and Bmf as regulators of hematopoietic stem and progenitor cell dynamics both during early engraftment and long-term reconstitution
our study suggests that Bad and Bmf co-regulate lymphocyte homeostasis and limit spontaneous transformation by mechanisms that may not exclusively be linked to the induction of lymphocyte apoptosis.
a potential role for Bmf in regulating renal proximal tubular cells (RPTC) apoptosis and tubular atrophy in diabetes.
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a single BCL2 homology domain 3 (BH3), and has been shown to bind BCL2 proteins and function as an apoptotic activator. This protein is found to be sequestered to myosin V motors by its association with dynein light chain 2, which may be important for sensing intracellular damage and triggering apoptosis. Alternatively spliced transcript variants encoding different isoforms have been identified.
Bcl2 modifying factor
, bcl-2-modifying factor
, Bcl-2 modifying factor
, Bcl-2-modifying factor