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anti-Beclin 1, Autophagy Related (BECN1) Antibodies

Beclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration (Zhong et al., 2009 [PubMed 19270693]).[supplied by OMIM, Jul 2010].. Additionally we are shipping Beclin 1 Kits (44) and Beclin 1 Proteins (19) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
BECN1 8678 Q14457
BECN1 56208 O88597
BECN1 114558 Q91XJ1
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Top anti-Beclin 1 Antibodies at antibodies-online.com

Showing 10 out of 367 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated IF, IHC (p), WB (LEFT)Western blot analysis of anti-BECN1 Mab (ABIN387797) in HepG2, 293, Jurkat and Hela cell line lysates (35 µg/lane). BECN1 (arrow) was detected using the Mab ascites (1:2000 dilution). (RIGHT)Western blot analysis of anti-BECN1 Mab (CA080116A) in recombinant BECN1 protein. BECN1(arrow) was detected using the ascites Mab (1:2000 dilution). Breast CA section stained with Autophagy Beclin 1 Antibody Cat. # ABIN387797 at a 1:50 dilution. Data courtesy of Dr. Anita Thyagarajan, Cancer Research Laboratory, Methodist Research Institute, Indianapolis, Indiana. 0.1 mL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB BECN1 Antibody (T72) (ABIN658010) western blot analysis in human normal Uterus cell line lysates (35 µg/lane). This demonstrates the BECN1 antibody detected the BECN1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-hBECN1-Q196 Pab (ABIN388545) in 293 cell line lysates transiently transfected with the BECN1 gene (2 µg/lane). hBECN1-Q196(arrow) was detected using the purified polyclonal antibody (1:30 dilution). The anti-BECN1 Pab (ABIN388545) is used in Western blot to detect BECN1 in mouse liver tissue lysate. BECN1(arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB The anti-BECN1 Pab (ABIN388546) is used in Western blot to detect BECN1 in, from left to right, A2058, Hela, mouse brain, Y79, and HL60 tissue lysates. BECN1(arrow) was detected using the purified polyclonal antibody. Western blot analysis of anti-hBECN1-E225 Pab (ABIN388546) in 293 cell line lysates transiently transfected with the BECN1 gene (2 µg/lane). hBECN1-E225(arrow) was detected using the purified polyclonal antibody (1:60 dilution). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated EIA, IHC (p), WB 0.1 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, IF, WB AP20057PU-N Beclin-1 antibody staining of A431 cells by Immunocytochemistry at 1 μg/ml. AP20057PU-N Beclin-1 antibody staining of A431 cells by Immunofluorescence at 2 μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Lane 1: mouse brain lysates Lane 2: mouse intestine lysates probed with Anti BECN1/Beclin 1/ATG6 Polyclonal Antibody, Unconjugated (ABIN675384) at 1:200 in 4C. Followed by conjugation to secondary antibody at 1:3000 90min in 37C. Predicted band 50kD. Formalin-fixed and paraffin embedded rabbit myocardium labeled with Anti-BECN1/Beclin 1/ATG6 Polyclonal Antibody, Unconjugated (ABIN675384) followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB AP20054PU-N Beclin-1 antibody staining of Rat brain tissue by Immunohistochemistry at 2 μg/ml. AP20054PU-N Beclin-1 antibody staining of 293 cell lysate by Western Blotting at (A) 0.5, (B) 1 and (C) 2 μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Mouse Un-conjugated FACS, IHC, ELISA, WB Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 ng), Blue: Antigen (100 ng) Figure 2: Flow cytometric analysis of RAJI cells using BECN1 mouse mAb (green) and negative control (purple) . 100 μL Log in to see 3 to 4 Days
$430.10
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-BECN1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: MCF7 cell lysate WB Suggested Anti-BECN1  Antibody Titration: 1 µg/mL  Positive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details

BECN1 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-Beclin 1 Antibodies

  1. Human Polyclonal Beclin 1 Primary Antibody for IHC (p), WB - ABIN388545 : Baehrecke: Autophagy: dual roles in life and death? in Nature reviews. Molecular cell biology 2005 (PubMed)
    Show all 10 references for ABIN388545

  2. Human Polyclonal Beclin 1 Primary Antibody for FACS, IHC (p) - ABIN388546 : Lum, DeBerardinis, Thompson: Autophagy in metazoans: cell survival in the land of plenty. in Nature reviews. Molecular cell biology 2005 (PubMed)
    Show all 10 references for ABIN388546

  3. Human Polyclonal Beclin 1 Primary Antibody for EIA, IHC (p) - ABIN497971 : Liang, Kleeman, Jiang, Gordon, Goldman, Berry, Herman, Levine: Protection against fatal Sindbis virus encephalitis by beclin, a novel Bcl-2-interacting protein. in Journal of virology 1998 (PubMed)
    Show all 6 references for ABIN497971

  4. Human Polyclonal Beclin 1 Primary Antibody for EIA, IF - ABIN497977 : Gozuacik, Kimchi: Autophagy as a cell death and tumor suppressor mechanism. in Oncogene 2004 (PubMed)
    Show all 6 references for ABIN497977

  5. Human Monoclonal Beclin 1 Primary Antibody for IF, IHC (p) - ABIN658976 : Metzger, Saukko, Van Che, Tong, Puder, Riess, Nguyen: Age at onset in Huntington's disease is modified by the autophagy pathway: implication of the V471A polymorphism in Atg7. in Human genetics 2010 (PubMed)
    Show all 5 references for ABIN658976

  6. Human Polyclonal Beclin 1 Primary Antibody for IF (p), IHC (p) - ABIN675384 : Tang, Li, Wei, Zhang, Chiu, Hasenmayer, Zhang, Zhang: Resveratrol-induced apoptosis is enhanced by inhibition of autophagy in esophageal squamous cell carcinoma. in Cancer letters 2013 (PubMed)
    Show all 3 references for ABIN675384

  7. Human Monoclonal Beclin 1 Primary Antibody for FACS, IHC - ABIN968976 : Zhong, Wang, Li, Yan, Backer, Chait, Heintz, Yue: Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex. in Nature cell biology 2009 (PubMed)
    Show all 3 references for ABIN968976

  8. Human Monoclonal Beclin 1 Primary Antibody for EIA, IHC (p) - ABIN1449374 : Starr, Child, Wehrly, Hansen, Hwang, López-Otin, Virgin, Celli: Selective subversion of autophagy complexes facilitates completion of the Brucella intracellular cycle. in Cell host & microbe 2012 (PubMed)
    Show all 2 references for ABIN1449374

  9. Human Polyclonal Beclin 1 Primary Antibody for WB - ABIN658010 : Oberstein, Jeffrey, Shi: Crystal structure of the Bcl-XL-Beclin 1 peptide complex: Beclin 1 is a novel BH3-only protein. in The Journal of biological chemistry 2007 (PubMed)

More Antibodies against Beclin 1 Interaction Partners

Zebrafish Beclin 1, Autophagy Related (BECN1) interaction partners

  1. Beclin1 plays an important role in vincristine-induced dopaminergic neurons toxicity.

Human Beclin 1, Autophagy Related (BECN1) interaction partners

  1. The casp3 (show CASP3 Antibodies) cleaved product of Beclin1 promotes apoptosis induced by S1 in SKOV3 cells.

  2. Suggest that Beclin 1 and p62 could serve as potential indicators for the prognosis of patients with non-small cell lung cancer.

  3. in-vitro genetic depletion of beclin-1 in high glucose treated adult rat cardiomyocytes markedly inhibited the level of autophagy and subsequent apoptotic cell death.

  4. these data indicate that IL-6 (show IL6 Antibodies) inhibits starvation-induced autophagy and that p-STAT3 (show STAT3 Antibodies) mediates the signal transduction from IL-6 (show IL6 Antibodies) to downstream proteins including Bcl-2 (show BCL2 Antibodies) and Beclin1

  5. Suggest high expression of Beclin-1 in alveolar macrophages could be a novel biomarker for predicting anti-TB outcomes.

  6. Beclin-1 role in antiviral immune responses: USP19 (show USP19 Antibodies) modulates antiviral immune responses by deubiquitinating Beclin-1.

  7. Autophagy defects caused by loss of Beclin 1 are not related to chemoresistance and metastasis, but may be associated with malignant phenotype and poor prognosis of ovarian clear cell carcinoma

  8. Decreased miR (show MLXIP Antibodies)-124-3p expression prompted breast cancer cell progression mainly by enhancing the expression of autophagy related protein, Beclin-1.

  9. this work makes novel observations about tumor expression of Beclin-1 and challenges the accepted understanding of its role in regulating autophagy in ovarian cancer.

  10. Data suggest that flexible helical domain of BECN1 undergoes a binding-associated disorder-to-helix transition; conserved residues critical for this interaction are essential for autophagy (here, autophagy induced by switching cells to EBSS).

Mouse (Murine) Beclin 1, Autophagy Related (BECN1) interaction partners

  1. in-vitro genetic depletion of beclin-1 in high glucose treated adult rat cardiomyocytes markedly inhibited the level of autophagy and subsequent apoptotic cell death.

  2. suggest that neuronal death induced by decreased beclin 1 levels may also be due to impaired trophic factor signaling

  3. FBG1 (show FBXO2 Antibodies) degrades A1AT (show SERPINA1 Antibodies)-Z through a Beclin1-dependent arm of autophagy.

  4. Beclin 1 is required for neuron viability and regulates endosome pathways via the UVRAG (show UVRAG Antibodies)-VPS34 (show PIK3C3 Antibodies) complex.

  5. a mechanism of inverse coregulation between BECN1 and MCL1 (show MCL1 Antibodies) significantly contributes to their opposing roles in tumorigenesis

  6. FKBP5 (show FKBP5 Antibodies) associates with BECN1, changes its phosphorylation and protein levels and enhances markers of autophagy and autophagic flux

  7. identifies a novel negative regulator of autophagy and suggests that RNF216 (show RNF216 Antibodies) may be a target for treatment of inflammatory diseases

  8. Inverse co-regulation of Beclin 1 and Mcl-1 (show MCL1 Antibodies) represents a mechanism of functional counteraction in cancer.

  9. Beclin 1-mediated autophagy alleviates cerebral ischemic injury following down-regulation of miRNA-30a.

  10. CFTR (show CFTR Antibodies) and BECN1 function can be restored with cysteamine and EGCG in a model of the F508del-CFTR (show CFTR Antibodies) mutation

Pig (Porcine) Beclin 1, Autophagy Related (BECN1) interaction partners

  1. Data indicate that the expression of MAP1LC3A (show MAP1LC3A Antibodies), B and autophagy-associated genes (ATG5 (show ATG5 Antibodies), mTOR (show FRAP1 Antibodies), Beclin-1) was increased in normal pigs, while decreased in miniature pigs.

Beclin 1 (BECN1) Antigen Profile

Protein Summary

Beclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration (Zhong et al., 2009

Gene names and symbols associated with BECN1

  • beclin 1, autophagy related (BECN1) antibody
  • beclin 1, autophagy related (becn1) antibody
  • beclin 1 (atg6) antibody
  • beclin 1 protein (atg6) antibody
  • beclin-1 (CpipJ_CPIJ011087) antibody
  • beclin-1 (PTRG_07825) antibody
  • beclin-1 (SJAG_01876) antibody
  • Beclin-1 (becn1) antibody
  • beclin 1 (coiled-coil, myosin-like BCL2 interacting protein) (becn1) antibody
  • beclin 1, autophagy related (Becn1) antibody
  • beclin-1-like (LOC100352353) antibody
  • 4921513J16Rik antibody
  • 5430417M23Rik antibody
  • Atg6 antibody
  • Beclin-1 antibody
  • beclin1 antibody
  • becn1 antibody
  • VPS30 antibody
  • zgc:73097 antibody

Protein level used designations for BECN1

beclin 1 (coiled-coil, myosin-like BCL2 interacting protein) , beclin-1 , beclin 1 , GRMZM2G092112 , beclin 1 proteinBeclin-1-like protein , Beclin-1 , myosin-like BCL2 interacting protein , ATG6 autophagy related 6 homolog , beclin 1 (coiled-coil, moesin-like BCL2 interacting protein) , beclin 1 (coiled-coil, moesin-like BCL2-interacting protein) , coiled-coil myosin-like BCL2-interacting protein , Bcl-2-interacting protein beclin , coiled-coil, myosin-like BCL2-interacting protein , beclin 1 (coiled-coil, myosin-like BCL2-interacting protein) , autophagy-related protein 6

GENE ID SPECIES
454700 Pan troglodytes
619357 Xenopus (Silurana) tropicalis
653027 Takifugu rubripes
711649 Macaca mulatta
732797 Zea mays
6043853 Culex quinquefasciatus
6346099 Pyrenophora tritici-repentis Pt-1C-BFP
7048057 Schizosaccharomyces japonicus yFS275
100049387 Oryzias latipes
100136134 Oncorhynchus mykiss
100173145 Pongo abelii
100194789 Salmo salar
393846 Danio rerio
8678 Homo sapiens
56208 Mus musculus
444178 Xenopus laevis
420018 Gallus gallus
733576 Sus scrofa
527278 Bos taurus
114558 Rattus norvegicus
480513 Canis lupus familiaris
100721231 Cavia porcellus
100913170 Ovis aries
100352353 Oryctolagus cuniculus
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