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anti-Beclin 1, Autophagy Related (BECN1) Antibodies

Beclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration (Zhong et al., 2009 [PubMed 19270693]).[supplied by OMIM, Jul 2010].. Additionally we are shipping Beclin 1 Kits (35) and Beclin 1 Proteins (19) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
BECN1 8678 Q14457
BECN1 56208 O88597
BECN1 114558 Q91XJ1
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Top anti-Beclin 1 Antibodies at antibodies-online.com

Showing 10 out of 430 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated IF, IHC (p), WB Western blot analysis of anti-BECN1 Monoclonal Antibody  in Jurkat cell line lysates (35ug/lane). BECN1 (arrow) was detected using the Mab ascites (1:100 dilution). Formalin-fixed and paraffin-embedded human brain with BECN1 Monoclonal Antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. 0.1 mL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB BECN1 Antibody (T72) (ABIN658010) western blot analysis in human normal Uterus cell line lysates (35 µg/lane). This demonstrates the BECN1 antibody detected the BECN1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-hBECN1-Q196 Pab (ABIN388545) in 293 cell line lysates transiently transfected with the BECN1 gene (2 µg/lane). hBECN1-Q196(arrow) was detected using the purified polyclonal antibody (1:30 dilution). The anti-BECN1 Pab (ABIN388545) is used in Western blot to detect BECN1 in mouse liver tissue lysate. BECN1(arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB The anti-BECN1 Pab (ABIN388546) is used in Western blot to detect BECN1 in, from left to right, A2058, Hela, mouse brain, Y79, and HL60 tissue lysates. BECN1(arrow) was detected using the purified polyclonal antibody. Western blot analysis of anti-hBECN1-E225 Pab (ABIN388546) in 293 cell line lysates transiently transfected with the BECN1 gene (2 µg/lane). hBECN1-E225(arrow) was detected using the purified polyclonal antibody (1:60 dilution). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated IHC, IHC (p), IP, WB Immunohistochemistry-Paraffin: Beclin 1/ATG6 Antibody (4H10) [NBP1-00085] - Staining of Beclin 1 in mouse lung. 0.1 mL Log in to see 5 to 7 Days
$408.19
Details
Chicken Mouse Un-conjugated IHC (p), IHC, WB Immunohistochemistry-Paraffin: Beclin 1/ATG6 Antibody (1B7) [NBP1-00084] - Staining of Beclin1 in mouse brain. 0.025 mL Log in to see 5 to 7 Days
$187.69
Details
Human Mouse Un-conjugated EIA, IHC (p), WB 0.1 mL Log in to see 6 to 8 Days
$390.50
Details
Dog Rabbit Un-conjugated ICC, IF, IHC, IHC (p), SimWes, WB Western Blot: Beclin 1 Antibody [ABIN259945] - Detection of Beclin 1 in HeLa whole cell lysate using ABIN259945 at 1:10,000. Immunohistochemistry-Paraffin: Beclin 1 Antibody [ABIN259945] - Staining of normal breast tissue using ABIN259945 (20x). 0.05 mL Log in to see 5 to 7 Days
$473.81
Details
Chicken Mouse Un-conjugated IHC, WB 0.1 mL Log in to see 5 to 7 Days
$381.94
Details
Human Rabbit Un-conjugated EIA, IF, WB AP20057PU-N Beclin-1 antibody staining of A431 cells by Immunocytochemistry at 1 μg/ml. AP20057PU-N Beclin-1 antibody staining of A431 cells by Immunofluorescence at 2 μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details

BECN1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Beclin 1 Antibodies

  1. Dog (Canine) Polyclonal Beclin 1 Primary Antibody for ICC, IF - ABIN259945 : Liang, Kleeman, Jiang, Gordon, Goldman, Berry, Herman, Levine: Protection against fatal Sindbis virus encephalitis by beclin, a novel Bcl-2-interacting protein. in Journal of virology 1998 (PubMed)
    Show all 29 references for ABIN259945

  2. Human Polyclonal Beclin 1 Primary Antibody for FACS, IHC (p) - ABIN388546 : Baehrecke: Autophagy: dual roles in life and death? in Nature reviews. Molecular cell biology 2005 (PubMed)
    Show all 10 references for ABIN388546

  3. Human Polyclonal Beclin 1 Primary Antibody for IHC (p), WB - ABIN388545 : Lum, DeBerardinis, Thompson: Autophagy in metazoans: cell survival in the land of plenty. in Nature reviews. Molecular cell biology 2005 (PubMed)
    Show all 10 references for ABIN388545

  4. Human Polyclonal Beclin 1 Primary Antibody for EIA, IF - ABIN497977 : Gozuacik, Kimchi: Autophagy as a cell death and tumor suppressor mechanism. in Oncogene 2004 (PubMed)
    Show all 6 references for ABIN497977

  5. Human Polyclonal Beclin 1 Primary Antibody for EIA, IHC (p) - ABIN497971 : Kametaka, Okano, Ohsumi, Ohsumi: Apg14p and Apg6/Vps30p form a protein complex essential for autophagy in the yeast, Saccharomyces cerevisiae. in The Journal of biological chemistry 1998 (PubMed)
    Show all 6 references for ABIN497971

  6. Human Monoclonal Beclin 1 Primary Antibody for IF, IHC (p) - ABIN658976 : Metzger, Saukko, Van Che, Tong, Puder, Riess, Nguyen: Age at onset in Huntington's disease is modified by the autophagy pathway: implication of the V471A polymorphism in Atg7. in Human genetics 2010 (PubMed)
    Show all 5 references for ABIN658976

  7. Chicken Monoclonal Beclin 1 Primary Antibody for IHC (p), IHC - ABIN314193 : Botbol, Patel, Macian: Common γ-chain cytokine signaling is required for macroautophagy induction during CD4+ T-cell activation. in Autophagy 2015 (PubMed)
    Show all 2 references for ABIN314193

  8. Human Monoclonal Beclin 1 Primary Antibody for EIA, IHC (p) - ABIN1449374 : Starr, Child, Wehrly, Hansen, Hwang, López-Otin, Virgin, Celli: Selective subversion of autophagy complexes facilitates completion of the Brucella intracellular cycle. in Cell host & microbe 2012 (PubMed)
    Show all 2 references for ABIN1449374

  9. Human Polyclonal Beclin 1 Primary Antibody for WB - ABIN658010 : Oberstein, Jeffrey, Shi: Crystal structure of the Bcl-XL-Beclin 1 peptide complex: Beclin 1 is a novel BH3-only protein. in The Journal of biological chemistry 2007 (PubMed)

  10. Chicken Monoclonal Beclin 1 Primary Antibody for IHC, WB - ABIN314196 : Sun, Li, Zhang, Chen, Zhang, Li, Deng, Qian, Jiao, Ji, Li, Wu, Yu, Feng, Zhu: Acetylation of Beclin 1 inhibits autophagosome maturation and promotes tumour growth. in Nature communications 2015 (PubMed)

More Antibodies against Beclin 1 Interaction Partners

Zebrafish Beclin 1, Autophagy Related (BECN1) interaction partners

  1. Beclin1 plays an important role in vincristine-induced dopaminergic neurons toxicity.

Human Beclin 1, Autophagy Related (BECN1) interaction partners

  1. High Beclin-1 expression (alone or in combination with SIRT1 (show SIRT1 Antibodies)) predicted shorter overall survival and relapse-free survival in gastric cancer.

  2. High-level oxidative stress appeared to suppress the protein levels of an autophagy-regulatory protein Beclin-1 in pediatric leukemia cells, possibly through induction of miR (show MLXIP Antibodies)-93, which inhibited the translation of Beclin-1 mRNA via 3'-UTR (show UTS2R Antibodies) binding.

  3. Beclin-1 was overexpressed in colorectal cancer tissues and was correlated with lower levels of miR (show MLXIP Antibodies)-30a. Patients with higher Beclin-1 expression levels had higher survival rates than patients with lower Beclin-1 expression levels.

  4. Both Beclin-1 and HIF-1alpha (show HIF1A Antibodies) could be considered as important biomarkers determinants of pathogenesis and survival in acute leukemia.

  5. Eleven primary Glioblastomas instead exhibited low beclin-1 expression and were positive for nuclear cyclin D1 (show CCND1 Antibodies); three of their recurrences exhibited an increase of beclin-1, which co-localized with cyclin D1 (show CCND1 Antibodies) in the cytoplasm. Our results suggest therapy-induced degradation of cyclin D1 (show CCND1 Antibodies) via autophagy

  6. The present study provides evidence that miR (show MLXIP Antibodies)-409-3p targets and inhibits Beclin-1, which inhibits chemotherapy-induced autophagy and thereby enhances the chemosensitivity of colon cancer cells.

  7. BECN1 N-terminal domain is intrinsically disordered.

  8. Beclin 1 and ATG5 play important roles in regulating both Obatoclax-induced autophagy and apoptosis in adenoid cystic carcinoma.

  9. we analyzed the expression status of BECN1 in AML (show RUNX1 Antibodies) and we found evidence for an association of reduced expression of BECN1 with FLT3 (show FLT3 Antibodies)-ITD mutation, adverse MK, higher age, and WBC count.

  10. Results of our present study demonstrated that beclin 1 and LC3 (show MAP1LC3A Antibodies) immunoreactivity increased in carcinoma cells following exemestane treatment and that the status of pre-treatment stromal beclin 1 is associated with higher carcinoma cell proliferation and poor clinical and pathological responses to NAE

Mouse (Murine) Beclin 1, Autophagy Related (BECN1) interaction partners

  1. provide the novel evidence that GADD45A (show GADD45A Antibodies) inhibits autophagy via impairing the BECN1-PIK3C3 (show PIK3C3 Antibodies) complex formation

  2. in-vitro genetic depletion of beclin-1 in high glucose treated adult rat cardiomyocytes markedly inhibited the level of autophagy and subsequent apoptotic cell death.

  3. suggest that neuronal death induced by decreased beclin 1 levels may also be due to impaired trophic factor signaling

  4. FBG1 (show FBXO2 Antibodies) degrades A1AT (show SERPINA1 Antibodies)-Z through a Beclin1-dependent arm of autophagy.

  5. Beclin 1 is required for neuron viability and regulates endosome pathways via the UVRAG (show UVRAG Antibodies)-VPS34 (show PIK3C3 Antibodies) complex.

  6. a mechanism of inverse coregulation between BECN1 and MCL1 (show MCL1 Antibodies) significantly contributes to their opposing roles in tumorigenesis

  7. FKBP5 (show FKBP5 Antibodies) associates with BECN1, changes its phosphorylation and protein levels and enhances markers of autophagy and autophagic flux

  8. identifies a novel negative regulator of autophagy and suggests that RNF216 (show RNF216 Antibodies) may be a target for treatment of inflammatory diseases

  9. Inverse co-regulation of Beclin 1 and Mcl-1 (show MCL1 Antibodies) represents a mechanism of functional counteraction in cancer.

  10. Beclin 1-mediated autophagy alleviates cerebral ischemic injury following down-regulation of miRNA-30a.

Pig (Porcine) Beclin 1, Autophagy Related (BECN1) interaction partners

  1. Data indicate that the expression of MAP1LC3A (show MAP1LC3A Antibodies), B and autophagy-associated genes (ATG5 (show ATG5 Antibodies), mTOR (show FRAP1 Antibodies), Beclin-1) was increased in normal pigs, while decreased in miniature pigs.

Beclin 1 (BECN1) Antigen Profile

Protein Summary

Beclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration (Zhong et al., 2009

Gene names and symbols associated with BECN1

  • beclin 1, autophagy related (BECN1) antibody
  • beclin 1, autophagy related (becn1) antibody
  • beclin 1 (atg6) antibody
  • beclin 1 protein (atg6) antibody
  • beclin-1 (CpipJ_CPIJ011087) antibody
  • beclin-1 (PTRG_07825) antibody
  • beclin-1 (SJAG_01876) antibody
  • Beclin-1 (becn1) antibody
  • beclin 1 (coiled-coil, myosin-like BCL2 interacting protein) (becn1) antibody
  • beclin 1, autophagy related (Becn1) antibody
  • beclin-1-like (LOC100352353) antibody
  • 4921513J16Rik antibody
  • 5430417M23Rik antibody
  • Atg6 antibody
  • Beclin-1 antibody
  • beclin1 antibody
  • becn1 antibody
  • VPS30 antibody
  • zgc:73097 antibody

Protein level used designations for BECN1

beclin 1 (coiled-coil, myosin-like BCL2 interacting protein) , beclin-1 , beclin 1 , GRMZM2G092112 , beclin 1 proteinBeclin-1-like protein , Beclin-1 , myosin-like BCL2 interacting protein , ATG6 autophagy related 6 homolog , beclin 1 (coiled-coil, moesin-like BCL2 interacting protein) , beclin 1 (coiled-coil, moesin-like BCL2-interacting protein) , coiled-coil myosin-like BCL2-interacting protein , Bcl-2-interacting protein beclin , coiled-coil, myosin-like BCL2-interacting protein , beclin 1 (coiled-coil, myosin-like BCL2-interacting protein) , autophagy-related protein 6

GENE ID SPECIES
454700 Pan troglodytes
619357 Xenopus (Silurana) tropicalis
653027 Takifugu rubripes
711649 Macaca mulatta
732797 Zea mays
6043853 Culex quinquefasciatus
6346099 Pyrenophora tritici-repentis Pt-1C-BFP
7048057 Schizosaccharomyces japonicus yFS275
100049387 Oryzias latipes
100136134 Oncorhynchus mykiss
100173145 Pongo abelii
100194789 Salmo salar
393846 Danio rerio
8678 Homo sapiens
56208 Mus musculus
444178 Xenopus laevis
420018 Gallus gallus
733576 Sus scrofa
527278 Bos taurus
114558 Rattus norvegicus
480513 Canis lupus familiaris
100721231 Cavia porcellus
100913170 Ovis aries
100352353 Oryctolagus cuniculus
Selected quality suppliers for anti-Beclin 1 (BECN1) Antibodies
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