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Beclin 1, Autophagy Related Proteins (BECN1)

Beclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration (Zhong et al., 2009 [PubMed 19270693]).[supplied by OMIM, Jul 2010].. Additionally we are shipping Beclin 1 Antibodies (367) and Beclin 1 Kits (44) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
BECN1 8678 Q14457
BECN1 56208 O88597
BECN1 114558 Q91XJ1
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Top Beclin 1 Proteins at antibodies-online.com

Showing 10 out of 19 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 20 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$785.40
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 56 to 66 Days
$3,246.83
Details
Yeast Xenopus tropicalis His tag   1 mg Log in to see 56 to 66 Days
$3,246.83
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$3,256.00
Details
Yeast Wild boar His tag   1 mg Log in to see 56 to 66 Days
$3,256.00
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,256.00
Details

BECN1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

Rat (Rattus)

Top referenced Beclin 1 Proteins

  1. Human Beclin 1 Protein expressed in Wheat germ - ABIN1346622 : Giatromanolaki, Koukourakis, Koutsopoulos, Chloropoulou, Liberis, Sivridis: High Beclin 1 expression defines a poor prognosis in endometrial adenocarcinomas. in Gynecologic oncology 2011 (PubMed)
    Show all 3 references for ABIN1346622

  2. Human Beclin 1 Protein expressed in Escherichia coli (E. coli) - ABIN1098220 : Itakura, Kishi, Inoue, Mizushima: Beclin 1 forms two distinct phosphatidylinositol 3-kinase complexes with mammalian Atg14 and UVRAG. in Molecular biology of the cell 2008 (PubMed)
    Show all 2 references for ABIN1098220

More Proteins for Beclin 1, Autophagy Related (BECN1) Interaction Partners

Zebrafish Beclin 1, Autophagy Related (BECN1) interaction partners

  1. Beclin1 plays an important role in vincristine-induced dopaminergic neurons toxicity.

Human Beclin 1, Autophagy Related (BECN1) interaction partners

  1. The casp3 (show CASP3 Proteins) cleaved product of Beclin1 promotes apoptosis induced by S1 in SKOV3 cells.

  2. Suggest that Beclin 1 and p62 could serve as potential indicators for the prognosis of patients with non-small cell lung cancer.

  3. in-vitro genetic depletion of beclin-1 in high glucose treated adult rat cardiomyocytes markedly inhibited the level of autophagy and subsequent apoptotic cell death.

  4. these data indicate that IL-6 (show IL6 Proteins) inhibits starvation-induced autophagy and that p-STAT3 (show STAT3 Proteins) mediates the signal transduction from IL-6 (show IL6 Proteins) to downstream proteins including Bcl-2 (show BCL2 Proteins) and Beclin1

  5. Suggest high expression of Beclin-1 in alveolar macrophages could be a novel biomarker for predicting anti-TB outcomes.

  6. Beclin-1 role in antiviral immune responses: USP19 modulates antiviral immune responses by deubiquitinating Beclin-1.

  7. Autophagy defects caused by loss of Beclin 1 are not related to chemoresistance and metastasis, but may be associated with malignant phenotype and poor prognosis of ovarian clear cell carcinoma

  8. Decreased miR (show MLXIP Proteins)-124-3p expression prompted breast cancer cell progression mainly by enhancing the expression of autophagy related protein, Beclin-1.

  9. this work makes novel observations about tumor expression of Beclin-1 and challenges the accepted understanding of its role in regulating autophagy in ovarian cancer.

  10. Data suggest that flexible helical domain of BECN1 undergoes a binding-associated disorder-to-helix transition; conserved residues critical for this interaction are essential for autophagy (here, autophagy induced by switching cells to EBSS).

Mouse (Murine) Beclin 1, Autophagy Related (BECN1) interaction partners

  1. in-vitro genetic depletion of beclin-1 in high glucose treated adult rat cardiomyocytes markedly inhibited the level of autophagy and subsequent apoptotic cell death.

  2. suggest that neuronal death induced by decreased beclin 1 levels may also be due to impaired trophic factor signaling

  3. FBG1 (show FBXO2 Proteins) degrades A1AT (show SERPINA1 Proteins)-Z through a Beclin1-dependent arm of autophagy.

  4. Beclin 1 is required for neuron viability and regulates endosome pathways via the UVRAG (show UVRAG Proteins)-VPS34 (show PIK3C3 Proteins) complex.

  5. a mechanism of inverse coregulation between BECN1 and MCL1 (show MCL1 Proteins) significantly contributes to their opposing roles in tumorigenesis

  6. FKBP5 (show FKBP5 Proteins) associates with BECN1, changes its phosphorylation and protein levels and enhances markers of autophagy and autophagic flux

  7. identifies a novel negative regulator of autophagy and suggests that RNF216 may be a target for treatment of inflammatory diseases

  8. Inverse co-regulation of Beclin 1 and Mcl-1 (show MCL1 Proteins) represents a mechanism of functional counteraction in cancer.

  9. Beclin 1-mediated autophagy alleviates cerebral ischemic injury following down-regulation of miRNA-30a.

  10. CFTR (show CFTR Proteins) and BECN1 function can be restored with cysteamine and EGCG in a model of the F508del-CFTR (show CFTR Proteins) mutation

Pig (Porcine) Beclin 1, Autophagy Related (BECN1) interaction partners

  1. Data indicate that the expression of MAP1LC3A (show MAP1LC3A Proteins), B and autophagy-associated genes (ATG5 (show ATG5 Proteins), mTOR (show FRAP1 Proteins), Beclin-1) was increased in normal pigs, while decreased in miniature pigs.

Beclin 1 (BECN1) Protein Profile

Protein Summary

Beclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration (Zhong et al., 2009

Gene names and symbols associated with BECN1

  • beclin 1, autophagy related (BECN1)
  • beclin 1, autophagy related (becn1)
  • beclin 1 (atg6)
  • beclin 1 protein (atg6)
  • beclin-1 (CpipJ_CPIJ011087)
  • beclin-1 (PTRG_07825)
  • beclin-1 (SJAG_01876)
  • Beclin-1 (becn1)
  • beclin 1 (coiled-coil, myosin-like BCL2 interacting protein) (becn1)
  • beclin 1, autophagy related (Becn1)
  • beclin-1-like (LOC100352353)
  • 4921513J16Rik protein
  • 5430417M23Rik protein
  • Atg6 protein
  • Beclin-1 protein
  • beclin1 protein
  • becn1 protein
  • VPS30 protein
  • zgc:73097 protein

Protein level used designations for BECN1

beclin 1 (coiled-coil, myosin-like BCL2 interacting protein) , beclin-1 , beclin 1 , GRMZM2G092112 , beclin 1 proteinBeclin-1-like protein , Beclin-1 , myosin-like BCL2 interacting protein , ATG6 autophagy related 6 homolog , beclin 1 (coiled-coil, moesin-like BCL2 interacting protein) , beclin 1 (coiled-coil, moesin-like BCL2-interacting protein) , coiled-coil myosin-like BCL2-interacting protein , Bcl-2-interacting protein beclin , coiled-coil, myosin-like BCL2-interacting protein , beclin 1 (coiled-coil, myosin-like BCL2-interacting protein) , autophagy-related protein 6

GENE ID SPECIES
454700 Pan troglodytes
619357 Xenopus (Silurana) tropicalis
653027 Takifugu rubripes
711649 Macaca mulatta
732797 Zea mays
6043853 Culex quinquefasciatus
6346099 Pyrenophora tritici-repentis Pt-1C-BFP
7048057 Schizosaccharomyces japonicus yFS275
100049387 Oryzias latipes
100136134 Oncorhynchus mykiss
100173145 Pongo abelii
100194789 Salmo salar
393846 Danio rerio
8678 Homo sapiens
56208 Mus musculus
444178 Xenopus laevis
420018 Gallus gallus
733576 Sus scrofa
527278 Bos taurus
114558 Rattus norvegicus
480513 Canis lupus familiaris
100721231 Cavia porcellus
100913170 Ovis aries
100352353 Oryctolagus cuniculus
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