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BEST4 is a member of the bestrophin gene family of anion channels. Additionally we are shipping Bestrophin 4 Antibodies (32) and many more products for this protein.
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BEST2 (show BEST2 Proteins) and BEST4 could be added to the lineage-specific genes of humans intestinal epithelial cells
identified three novel VMD2 (show BEST1 Proteins)-related human genes demonstrating a high degree of conservation in their respective RFP (show FPR2 Proteins)-TM domains
Human Best4 chloride channels on excised membrane patches can be activated by free calcium (Ca2 (show CA2 Proteins)+) on the cytoplasmic side.
This gene is a member of the bestrophin gene family of anion channels. Bestrophin genes share a similar gene structure with highly conserved exon-intron boundaries, but with distinct 3' ends. Bestrophins are transmembrane proteins that contain a homologous region rich in aromatic residues, including an invariant arg-phe-pro motif. Mutation in one of the family members (bestrophin 1) is associated with vitelliform macular dystrophy. The bestrophin 4 gene is predominantly expressed in the colon.
, vitelliform macular dystrophy 2-like 2
, vitelliform macular dystrophy 2-like protein 2