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BHMT encodes a cytosolic enzyme that catalyzes the conversion of betaine and homocysteine to dimethylglycine and methionine, respectively. Additionally we are shipping BHMT Proteins (13) and BHMT Kits (1) and many more products for this protein.
Showing 10 out of 134 products:
Human Monoclonal BHMT Primary Antibody for EIA, WB - ABIN1105529
McKeever, Weir, Molloy, Scott: Betaine-homocysteine methyltransferase: organ distribution in man, pig and rat and subcellular distribution in the rat. in Clinical science (London, England : 1979) 1991
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Human Polyclonal BHMT Primary Antibody for ELISA, WB - ABIN334358
Collinsova, Strakova, Jiracek, Garrow: Inhibition of betaine-homocysteine S-methyltransferase causes hyperhomocysteinemia in mice. in The Journal of nutrition 2006
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Human Polyclonal BHMT Primary Antibody for ELISA, IHC - ABIN314263
Geillinger, Rathmann, Köhrle, Fiamoncini, Daniel, Kipp: Hepatic metabolite profiles in mice with a suboptimal selenium status. in The Journal of nutritional biochemistry 2014
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Chicken Polyclonal BHMT Primary Antibody for IHC, WB - ABIN2773785
Castro, Gratson, Evans, Jiracek, Collinsová, Ludwig, Garrow: Dissecting the catalytic mechanism of betaine-homocysteine S-methyltransferase by use of intrinsic tryptophan fluorescence and site-directed mutagenesis. in Biochemistry 2004
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Human Monoclonal BHMT Primary Antibody for IHC, ELISA - ABIN968978
Gerhard, Wagner, Feingold, Shenmen, Grouse, Schuler, Klein, Old, Rasooly, Good, Guyer, Peck, Derge, Lipman, Collins, Jang, Sherry, Feolo, Misquitta, Lee, Rotmistrovsky, Greenhut, Schaefer, Buetow et al.: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ... in Genome research 2004
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Dog (Canine) Polyclonal BHMT Primary Antibody for EIA, IHC (p) - ABIN375080
Ryu, Kwak, Lee, Kang, Oh, Lee, Kim, Ma, Kim: Sulfur amino acid metabolism in doxorubicin-resistant breast cancer cells. in Toxicology and applied pharmacology 2011
The faster evolutionary rate of BHMT2 (show BHMT2 Antibodies) overall suggests that selective constraints were reduced relative to BHMT.
Multiple SNPs in BHMT and BHMT2 (show BHMT2 Antibodies) were identified to be associated with the occurrence of infant obstructive heart defects and interaction effects with maternal use of folic acid supplements.
Data suggest BHMT is activated by binding of potassium ions; role of potassium ions in BHMT appears to be structural; potassium ions facilitate specific binding of substrate homocysteine (rather than substrate betaine) to active site of the enzyme.
Study suggests BHMT holds considerable potential as a blood biomarker for acute liver injury.
Women harboring the single nucleotide polymorphism BHMT 742G>A have a decreased risk of a Down Syndrome pregnancy.
Known common single-nucleotide polymorphisms in MTRR (show MTRR Antibodies) and BHMT genes may not be significant risk factors for cororonary artery disease.
Our study suggests that the polymorphism BHMT G742A may modulate the Down syndrome risk in Brazilian mothers.
The BHMT 742GA or AA genotypes associated with tobacco consumption (P = 0.016) increase the risk for head and neck squamous cell carcinoma.
A transcription variant of exon 4 of betaine-homocysteine methyltransferase (BHMT) produces a loss of function of BHMT in human hepatocarcinoma
Three SNPs (rs41272270, rs16876512, and rs6875201), located 28kb upstream, in the 5'-UTR (show UTS2R Antibodies) and in intron 1 of BHMT, respectively, were significantly correlated with both BHMT activity and protein levels.
It was concluded that the BHMT pathway is a major route for the elimination of Hcy in mice and that the methionine synthase (show MTR Antibodies) pathway has little excess capacity to methylate the Hcy that accumulates when the BHMT pathway is blocked.
mouse blastocysts are unusual in being able to generate AdoMet (show MAT1A Antibodies) not only by the ubiquitous folate-dependent mechanism but also from betaine metabolized by BHMT
a role for BHMT in energy homeostasis.
BHMT has an important role in Hcy, choline, and one-carbon homeostasis
The BHMT/betaine system directly protects hepatocytes from homocysteine-induced injury but not tunicamycin-induced injury, including an endoplasmic reticulum stress response, lipid accumulation, and cell death.
function for Bhmt involving modulation of Shh (show SHH Antibodies) signaling to control beta-cell development.
This gene encodes a cytosolic enzyme that catalyzes the conversion of betaine and homocysteine to dimethylglycine and methionine, respectively. Defects in this gene could lead to hyperhomocyst(e)inemia, but such a defect has not yet been observed.
betaine--homocysteine S-methyltransferase 1
, betaine-homocysteine methyltransferase