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Betaine--Homocysteine S-Methyltransferase Proteins (BHMT)

BHMT encodes a cytosolic enzyme that catalyzes the conversion of betaine and homocysteine to dimethylglycine and methionine, respectively. Additionally we are shipping BHMT Antibodies (133) and BHMT Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
BHMT 635 Q93088
BHMT 12116 O35490
BHMT 81508 O09171
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Top BHMT Proteins at antibodies-online.com

Showing 10 out of 13 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 11 to 12 Days
$246.96
Details
Yeast Wild boar His tag   1 mg Log in to see 56 to 66 Days
$2,724.33
Details
Yeast Zebrafish His tag   1 mg Log in to see 56 to 66 Days
$3,107.50
Details
Yeast Xenopus tropicalis His tag   1 mg Log in to see 56 to 66 Days
$3,116.67
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$3,125.83
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,125.83
Details
HOST_Escherichia coli (E. coli) Human His tag   50 μg Log in to see 3 to 4 Days
$190.93
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$273.57
Details

BHMT Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Rat (Rattus)

More Proteins for Betaine--Homocysteine S-Methyltransferase (BHMT) Interaction Partners

Human Betaine--Homocysteine S-Methyltransferase (BHMT) interaction partners

  1. The faster evolutionary rate of BHMT2 (show BHMT2 Proteins) overall suggests that selective constraints were reduced relative to BHMT.

  2. Multiple SNPs in BHMT and BHMT2 (show BHMT2 Proteins) were identified to be associated with the occurrence of infant obstructive heart defects and interaction effects with maternal use of folic acid supplements.

  3. Data suggest BHMT is activated by binding of potassium ions; role of potassium ions in BHMT appears to be structural; potassium ions facilitate specific binding of substrate homocysteine (rather than substrate betaine) to active site of the enzyme.

  4. Study suggests BHMT holds considerable potential as a blood biomarker for acute liver injury.

  5. Women harboring the single nucleotide polymorphism BHMT 742G>A have a decreased risk of a Down Syndrome pregnancy.

  6. Known common single-nucleotide polymorphisms in MTRR (show MTRR Proteins) and BHMT genes may not be significant risk factors for cororonary artery disease.

  7. Our study suggests that the polymorphism BHMT G742A may modulate the Down syndrome risk in Brazilian mothers.

  8. The BHMT 742GA or AA genotypes associated with tobacco consumption (P = 0.016) increase the risk for head and neck squamous cell carcinoma.

  9. A transcription variant of exon 4 of betaine-homocysteine methyltransferase (BHMT) produces a loss of function of BHMT in human hepatocarcinoma

  10. Three SNPs (rs41272270, rs16876512, and rs6875201), located 28kb upstream, in the 5'-UTR and in intron 1 of BHMT, respectively, were significantly correlated with both BHMT activity and protein levels.

Mouse (Murine) Betaine--Homocysteine S-Methyltransferase (BHMT) interaction partners

  1. It was concluded that the BHMT pathway is a major route for the elimination of Hcy in mice and that the methionine synthase (show MTR Proteins) pathway has little excess capacity to methylate the Hcy that accumulates when the BHMT pathway is blocked.

  2. mouse blastocysts are unusual in being able to generate AdoMet (show MAT1A Proteins) not only by the ubiquitous folate-dependent mechanism but also from betaine metabolized by BHMT

  3. a role for BHMT in energy homeostasis.

  4. BHMT has an important role in Hcy, choline, and one-carbon homeostasis

  5. The BHMT/betaine system directly protects hepatocytes from homocysteine-induced injury but not tunicamycin-induced injury, including an endoplasmic reticulum stress response, lipid accumulation, and cell death.

Zebrafish Betaine--Homocysteine S-Methyltransferase (BHMT) interaction partners

  1. function for Bhmt involving modulation of Shh (show SHH Proteins) signaling to control beta-cell development.

BHMT Protein Profile

Protein Summary

This gene encodes a cytosolic enzyme that catalyzes the conversion of betaine and homocysteine to dimethylglycine and methionine, respectively. Defects in this gene could lead to hyperhomocyst(e)inemia, but such a defect has not yet been observed.

Gene names and symbols associated with BHMT

  • betaine--homocysteine S-methyltransferase (BHMT)
  • betaine--homocysteine S-methyltransferase (bhmt)
  • betaine-homocysteine methyltransferase (Bhmt)
  • betaine-homocysteine methyltransferase (bhmt)
  • betaine-homocysteine S-methyltransferase (Bhmt)
  • BHMT1 protein
  • hm:zehn2153 protein
  • wu:fb53h01 protein
  • wu:fb63c08 protein
  • wu:fj64d01 protein
  • zgc:123027 protein

Protein level used designations for BHMT

betaine--homocysteine S-methyltransferase 1 , betaine-homocysteine methyltransferase

GENE ID SPECIES
635 Homo sapiens
495275 Xenopus laevis
416371 Gallus gallus
479171 Canis lupus familiaris
397371 Sus scrofa
497025 Bos taurus
101113853 Ovis aries
12116 Mus musculus
322228 Danio rerio
81508 Rattus norvegicus
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