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displays differential expression in a model of liver cirrhosis [RGD, Feb 2006].. Additionally we are shipping BHMT Kits (5) and BHMT Antibodies (5) and many more products for this protein.
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Human BHMT Protein expressed in Escherichia coli (E. coli) - ABIN666859
Breksa, Garrow: Recombinant human liver betaine-homocysteine S-methyltransferase: identification of three cysteine residues critical for zinc binding. in Biochemistry 1999
Show all 2 references for ABIN666859
BHMT expression is robustly regulated by taurine.
It was concluded that the BHMT pathway is a major route for the elimination of Hcy in mice and that the methionine synthase (show MTR Proteins) pathway has little excess capacity to methylate the Hcy that accumulates when the BHMT pathway is blocked.
mouse blastocysts are unusual in being able to generate AdoMet (show MAT1A Proteins) not only by the ubiquitous folate-dependent mechanism but also from betaine metabolized by BHMT
a role for BHMT in energy homeostasis.
BHMT has an important role in Hcy, choline, and one-carbon homeostasis
The BHMT/betaine system directly protects hepatocytes from homocysteine-induced injury but not tunicamycin-induced injury, including an endoplasmic reticulum stress response, lipid accumulation, and cell death.
displays differential expression in a model of liver cirrhosis
, betaine--homocysteine S-methyltransferase 1
, betaine--homocysteine S-methyltransferase
, betaine--homocysteine S-methyltransferase 1-like