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Bicaudal D Homolog 2 (Drosophila) (BICD2) ELISA Kits

BICD2 is one of two human homologs of Drosophila bicaudal-D and a member of the Bicoid family. Additionally we are shipping BICD2 Antibodies (33) and and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human BICD2 BICD2 23299 Q8TD16
Anti-Mouse BICD2 BICD2 76895 Q921C5
Anti-Rat BICD2 BICD2 306809  
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More ELISA Kits for BICD2 Interaction Partners

Human Bicaudal D Homolog 2 (Drosophila) (BICD2) interaction partners

  1. several analyses of vesicular transport demonstrated that Rab6A (show RAB6A ELISA Kits) and BICD2 play crucial roles in Golgi tubule fusion with the endoplasmic reticulum (ER) in brefeldin A (BFA)-treated cells

  2. the features of BICD2 spinal muscular atrophy, lower extremity predominant are consistent with a pathological process that preferentially affects lumbar lower motor neurons

  3. Mutations in BICD2 cause congenital autosomal-dominant spinal muscular atrophy and massive Golgi fragmentation in affected cells.

  4. BICD2 mutations cause non-5q linked spinal muscular atrophy in humans

  5. Disease causing mutations resulting in amino acid substitutions in two binding regions of BICD2 increase its binding affinity for the cytoplasmic dynein (show DYNC1H1 ELISA Kits)-dynactin (show DCTN1 ELISA Kits) complex.

  6. Data suggest that ASUN promotes perinuclear enrichment of dynein at G2/M that facilitates BICD2- and CENP-F-mediated anchoring of dynein to nuclear pore complexes.

  7. isolation, cloning, and characterization of human Nek8 (show NEK9 ELISA Kits), a new mammalian NIMA-related kinase, and its candidate substrate Bicd2

Mouse (Murine) Bicaudal D Homolog 2 (Drosophila) (BICD2) interaction partners

  1. several analyses of vesicular transport demonstrated that Rab6A (show RAB6A ELISA Kits) and BICD2 play crucial roles in Golgi tubule fusion with the endoplasmic reticulum (ER) in brefeldin A (BFA)-treated cells

  2. Data indicate that Bicaudal-D2 (BICD2)-deficient mice develop disrupted laminar organization of cerebral cortex and the cerebellum, pointing to impaired radial neuronal migration.

  3. LIS1 (show PAFAH1B1 ELISA Kits) is required for dynein-mediated transport induced by membrane tethering of BICD2-N and LIS1 (show PAFAH1B1 ELISA Kits) contributes to dynein accumulation at microtubule plus ends and BICD2-positive cellular structures.

  4. BICD2-N transgene increased lifespan in 'low copy' SOD1-G93A ALS transgenic mice.

BICD2 Antigen Profile

Antigen Summary

This gene is one of two human homologs of Drosophila bicaudal-D and a member of the Bicoid family. It has been implicated in dynein-mediated, minus end-directed motility along microtubules. It has also been reported to be a phosphorylation target of NIMA related kinase 8. Two alternative splice variants have been described.

Gene names and symbols associated with BICD2

  • bicaudal D homolog 2 (Drosophila) (BICD2) antibody
  • zgc:171572 (zgc:171572) antibody
  • bicaudal D homolog 2 (bicd2) antibody
  • bicaudal D homolog 2 (LOC100348480) antibody
  • bicaudal D homolog 2 (LOC100351714) antibody
  • bicaudal D homolog 2 (Drosophila) (bicd2) antibody
  • bicaudal D homolog 2 (Drosophila) (Bicd2) antibody
  • 0610027D24Rik antibody
  • 1110005D12Rik antibody
  • AA408834 antibody
  • bA526D8.1 antibody
  • bicd2 antibody
  • MGC84972 antibody
  • mKIAA0699 antibody
  • SMALED2 antibody

Protein level used designations for BICD2

protein bicaudal D homolog 2 , bicaudal D homolog 2 (Drosophila) , bicaudal D homolog 2 , protein bicaudal D homolog 2-like , bic-D 2 , coiled-coil protein BICD2 , cytoskeleton-like bicaudal D protein homolog 2 , homolog of Drosophila bicaudal D , bicaudal D protein

GENE ID SPECIES
282447 Bos taurus
415990 Gallus gallus
465233 Pan troglodytes
484214 Canis lupus familiaris
562424 Danio rerio
706621 Macaca mulatta
734304 Xenopus laevis
100014670 Monodelphis domestica
100056101 Equus caballus
100227228 Taeniopygia guttata
100327237 Xenopus (Silurana) tropicalis
100348480 Oryctolagus cuniculus
100351714 Oryctolagus cuniculus
100472389 Ailuropoda melanoleuca
100490789 Xenopus (Silurana) tropicalis
100447092 Pongo abelii
100512597 Sus scrofa
100545283 Meleagris gallopavo
100555618 Anolis carolinensis
23299 Homo sapiens
76895 Mus musculus
306809 Rattus norvegicus
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