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The protein encoded by BGN is a small cellular or pericellular matrix proteoglycan that is closely related in structure to two other small proteoglycans, decorin and fibromodulin. Additionally we are shipping Biglycan Kits (27) and Biglycan Proteins (27) and many more products for this protein.
Showing 10 out of 112 products:
Human Monoclonal Biglycan Primary Antibody for WB - ABIN393299
Yang, Burch, Getachew, Ballinger, Osman, Little: Growth factor-mediated hyper-elongation of glycosaminoglycan chains on biglycan requires transcription and translation. in Archives of physiology and biochemistry 2009
Show all 5 references for ABIN393299
Human Polyclonal Biglycan Primary Antibody for EIA, IHC (p) - ABIN452781
Sardo, Mandraffino, Campo, Saitta, Bitto, Alibrandi, Riggio, Imbalzano, Saitta: Biglycan expression in hypertensive subjects with normal or increased carotid intima-media wall thickness. in Clinica chimica acta; international journal of clinical chemistry 2009
Show all 2 references for ABIN452781
Human Polyclonal Biglycan Primary Antibody for IHC, ELISA - ABIN334359
Chen, Lenschow, Tiede, Fischer, Kalthoff, Ungefroren: Smad4/DPC4-dependent regulation of biglycan gene expression by transforming growth factor-beta in pancreatic tumor cells. in The Journal of biological chemistry 2002
Show all 2 references for ABIN334359
Human Polyclonal Biglycan Primary Antibody for IF (p), IHC (p) - ABIN872817
Huang, Zou, Shi, Zhang, Pen, Zhang, Gao, Wang: The effect of electroacupuncture on the extracellular matrix synthesis and degradation in a rabbit model of disc degeneration. in Evidence-based complementary and alternative medicine : eCAM 2014
Human Monoclonal Biglycan Primary Antibody for IHC (p), IP - ABIN560056
Zhang, Lee, Young, Wang: The Small Leucine-Rich Proteoglycan BGN Accumulates in CADASIL and Binds to NOTCH3. in Translational stroke research 2015
Human Polyclonal Biglycan Primary Antibody for FACS, IHC (p) - ABIN390701
Traupe, van den Ouweland, van Oost, Vogel, Vetter, Warren, Rocchi, Darlison, Ropers: Fine mapping of the human biglycan (BGN) gene within the Xq28 region employing a hybrid cell panel. in Genomics 1992
Cow (Bovine) Polyclonal Biglycan Primary Antibody for WB - ABIN2786644
Gogiel, Galewska, Romanowicz, Jaworski, Bańkowski: Pre-eclampsia-associated alterations in decorin, biglycan and versican of the umbilical cord vein wall. in European journal of obstetrics, gynecology, and reproductive biology 2007
Dog (Canine) Polyclonal Biglycan Primary Antibody for EIA, WB - ABIN375174
Burssens, Forsyth, Bongaerts, Jagodzinski, Mahieu, Praet, Victor: Arguments for an increasing differentiation towards fibrocartilaginous components in midportion Achilles tendinopathy. in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA 2013
biglycan exerts an important role in cell proliferation, migration, invasion and apoptosis in colon cancer.
BGN might play an important role on metastasis in human endometrial cancer and it might be a target marker for the molecular therapy of advanced and recurrence endometrial cancer.
This study demonstrated that the small leucine-rich proteoglycan (show Vcan Antibodies) BGN accumulates in CADASIL (show NOTCH3 Antibodies) and binds to NOTCH3 (show NOTCH3 Antibodies).
Biglycan may have a role in development of vascular damage in smokers
BGN is a factor secreted by peritubular cells to modulate FGFR3c signaling and thus contributes to the regulation of spermatogonial maintenance
The results suggest that regions within BGN is associated with ACL (show ACLY Antibodies) injury susceptibility and that genetic sequence variability within genes encoding proteoglycans may potentially modulate the ligament fibril properties.
immunolocalization of decorin (show DCN Antibodies) and biglycan in samples of first-trimester and term placentas, placenta accreta, invasive mole, and choriocarcinoma
Biglycan modulates angiogenesis and bone formation during fracture healing.
Data indicate that the biglycan (BGN) CC genotype was significantly over-represented in the control group versus the carpal tunnel syndrome (CTS (show TTR Antibodies)) group.
High expression of BGN in esophageal squamous cell carcinoma indicated aggressive tumor behaviors and predicted a worse clinical outcome.
Importance of biglycan and decorin (show DCN Antibodies) as targets for the manipulation of fetal membrane extracellular matrix stability in the context of inflammation.
Biglycan deficiency leads to loosely packed aortic collagen fibers, increased susceptibility of aortic elastin (show ELN Antibodies) fibers to angII-induced stress, and up-regulation of vascular perlecan (show HSPG2 Antibodies) content.
Biglycan signaling supported fetal membrane remodeling during early gestation in the absence of concomitant changes in TGFbeta (show TGFB1 Antibodies) levels.
Lumican (show LUM Antibodies) and biglycan influence corneal keratocyte lamellipodia organization and are critical in the regulation of stromal collagen fibrillogenesis.
Biglycan-triggered TLR-2 (show TLR2 Antibodies)- and TLR-4 (show TLR4 Antibodies)-signaling exacerbates the pathophysiology of ischemic acute kidney injury.
De novo expression of circulating biglycan evokes an innate inflammatory tissue response via MyD88 (show MYD88 Antibodies)/TRIF (show RNF138 Antibodies) pathways.
Early stage patellar tendon healing was inferior in biglycan-null and decorin (show DCN Antibodies)-null mice as compared to wild type.
This suggests that biglycan and decorin (show DCN Antibodies) may have sequential roles in the tendon response to injury.
Mast cell chymase (show CMA1 Antibodies) degrades the alarmins heat shock protein 70 (show HSP70 Antibodies), biglycan, HMGB1 (show HMGB1 Antibodies), and interleukin-33 (IL-33 (show IL33 Antibodies)) and limits danger-induced inflammation.
extracellular matrix biglycan mediates breast cancer normalization induced by embryonic mesenchyme
Bgn regulates BMP4 (show BMP4 Antibodies) signaling through modulation of Chordin (show CHRD Antibodies) anti-BMP4 (show BMP4 Antibodies) activity.
LDL electrostatic interactions with decorin (show DCN Antibodies) and biglycan in the aortic valve leaflets and vascular wall is a major source of LDL retention.
Data show that biglycan, collagen type I, collagen type II, decorin (show DCN Antibodies), and versican (show Vcan Antibodies) were significantly affected by vibration duration, frequency, and amplitude.
biglycan showed a unique ability to organize collagen VI into extensive hexagonal-like networks over a time period of only a few minutes
biglycan-induced fibroblast cytoskeletal and signalling changes result in an increased cell migration; potential role in the remodelling process
The results indicate that CTGF (show CTGF Antibodies) suppresses the synthesis of biglycan but newly induced that of decorin (show DCN Antibodies) in the cells when the cell density is low.
The protein encoded by this gene is a small cellular or pericellular matrix proteoglycan that is closely related in structure to two other small proteoglycans, decorin and fibromodulin. The encoded protein and decorin are thought to be the result of a gene duplication. Decorin contains one attached glycosaminoglycan chain, while this protein probably contains two chains. For this reason, this protein is called biglycan. This protein plays a role in assembly of collagen fibrils and muscle regeneration. It interacts with several proteins involved in muscular dystrophy, including alpha-dystroglycan, alpha- and gamma-sarcoglycan and collagen VI, and it is critical for the assembly of the dystrophin-associated protein complex.
, biglycan proteoglycan
, bone/cartilage proteoglycan I
, bone/cartilage proteoglycan-I
, dermatan sulphate proteoglycan I
, small leucine-rich protein 1A
, Small proteoglycan I (biglycan), bone (BSPG1) (bone/cartilage proteclycan 1 precursor)
, bone/cartilage proteclycan 1
, leucine-rich PG I