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Biotin-Protein Ligase (HLCS) ELISA Kits

HLCS encodes an enzyme that catalyzes the binding of biotin to carboxylases and histones. Additionally we are shipping Biotin-Protein Ligase Antibodies (26) and Biotin-Protein Ligase Proteins (5) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
HLCS 110948 Q920N2
HLCS 3141 P50747
Anti-Rat HLCS HLCS 288240  
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More ELISA Kits for Biotin-Protein Ligase Interaction Partners

Human Biotin-Protein Ligase (HLCS) interaction partners

  1. The transcriptional function of HCS was shown by in vitro pull down and in vivo co-immunoprecipitation assays to depend on its interaction with the histone deacetylases HDAC1 (show HDAC1 ELISA Kits), HDAC2 (show HDAC2 ELISA Kits) and HDAC7 (show HDAC7 ELISA Kits)

  2. Data suggest that direct interactions of HLCS (holocarboxylase synthetase) with NCOR1 (nuclear receptor corepressor 1 (show NCOR1 ELISA Kits)) and HDAC1 (histone deacetylase 1 (show HDAC1 ELISA Kits)) contribute toward transcriptional repression of repeats, presumably increasing genome stability.

  3. study characterizes three functional promoters in the human HLCS gene

  4. HLCS interacts physically with the DNA methyltransferase (show DNMT1 ELISA Kits) DNMT1 (show DNMT1 ELISA Kits) and the methyl CpG binding protein MeCP2 (show MECP2 ELISA Kits) to facilitate the binding of HLCS to chromatin.

  5. This study showed that modification of HSP72 (show HSPA1A ELISA Kits) and demonstrated that binding of biotin to extracellular HSP72 (show HSPA1A ELISA Kits) prepares cells for a strong immune response.

  6. individuals with HLCS SNPs may benefit from supplemental biotin, yet to different extents depending on the genotype

  7. HLCS methionine-58 is a functional translation start site in human cells.

  8. Holocarboxylase synthetase interacts directly with histone H3 (show HIST3H3 ELISA Kits), causing biotinylation of lysine K9 and K18 (show KRT18 ELISA Kits).

  9. Mutation analysis by polymerase chain reaction-sequencing of the entire coding region of the HLCS gene revealed the c.1522C>T (p.R508W) mutation in six of the eight mutant alleles. suggests it as the most common mutation in the Thai population

  10. The results of this study suggest that miR (show MLXIP ELISA Kits)-539 is among the factors sensing biotin and regulating holocarboxylase synthetase expression.

Biotin-Protein Ligase (HLCS) Antigen Profile

Antigen Summary

This gene encodes an enzyme that catalyzes the binding of biotin to carboxylases and histones. The protein plays an important role in gluconeogenesis, fatty acid synthesis and branched chain amino acid catabolism. Defects in this gene are the cause of holocarboxylase synthetase deficiency. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Gene names and symbols associated with Biotin-Protein Ligase (HLCS) ELISA Kits

  • holocarboxylase synthetase (biotin- [propriony-Coenzyme A-carboxylase (ATP-hydrolysing)] ligase) (Hlcs) antibody
  • holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) (HLCS) antibody
  • holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) (Hlcs) antibody
  • 410I21.SP6 antibody
  • D16Jhu34 antibody
  • HCS antibody
  • RGD1565360 antibody

Protein level used designations for Biotin-Protein Ligase (HLCS) ELISA Kits

biotin apo-protein ligase , biotin- [propriony-Coenzyme A-carboxylase (ATP-hydrolysing)] ligase , biotin--protein ligase , biotin--[acetyl-CoA-carboxylase] ligase , biotin--[methylcrotonoyl-CoA-carboxylase] ligase , biotin--[methylmalonyl-CoA-carboxytransferase] ligase , holocarboxylase synthetase (biotin-(proprionyl-Coenzyme A-carboxylase (ATP-hydrolysing)) ligase) , holocarboxylase synthetase (biotin- [propriony-Coenzyme A-carboxylase (ATP-hydrolysing)] ligase)

110948 Mus musculus
3141 Homo sapiens
288240 Rattus norvegicus
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