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anti-Bleomycin Hydrolase (BLMH) Antibodies

Bleomycin hydrolase (BMH) is a cytoplasmic cysteine peptidase that is highly conserved through evolution\; however, the only known activity of the enzyme is metabolic inactivation of the glycopeptide bleomycin (BLM), an essential component of combination chemotherapy regimens for cancer. Additionally we are shipping BLMH Proteins (23) and BLMH Kits (11) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
BLMH 104184 Q8R016
BLMH 287552  
BLMH 642 Q13867
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Top anti-BLMH Antibodies at antibodies-online.com

Showing 10 out of 79 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-BLMH Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: 721_B cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated WB BLMH monoclonal antibody (M02), clone 4A2. Western Blot analysis of BLMH expression in K-562. Detection limit for recombinant GST tagged BLMH is approximately 0.3 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated WB BLMH Antibody (Center) (ABIN1881112) western blot analysis in CEM,HL-60 cell line lysates (35 µg/lane). This demonstrates the BLMH antibody detected the BLMH protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB BLMH Antibody (Center) (ABIN1881113) western blot analysis in K562 cell line,mouse stomach and rat stomach tissue lysates (35 µg/lane). This demonstrates the BLMH antibody detected the BLMH protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB Host: Rabbit  Target Name: Blmh  Sample Tissue: Mouse Stomach lysates  Antibody Dilution: 1.0 µg/mL 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated ELISA, WB BLMH polyclonal antibody (A01), Lot # 060111JC01 Western Blot analysis of BLMH expression in 293 . Western Blot detection against Immunogen (37 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Human Rabbit Un-conjugated WB WB Image Sample (30 ug of whole cell lysate) A: A549 10% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 8 to 10 Days
$507.83
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Mouse Un-conjugated DB 50 μg Log in to see 7 to 9 Days
$285.71
Details

BLMH Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-BLMH Antibodies

  1. Human Monoclonal BLMH Primary Antibody for WB - ABIN396175 : Sowa, Bennett, Gygi, Harper: Defining the human deubiquitinating enzyme interaction landscape. in Cell 2009 (PubMed)
    Show all 5 references for ABIN396175

  2. Human Polyclonal BLMH Primary Antibody for WB - ABIN1881112 : Ferrando, Velasco, Campo, Lopez-Otin: Cloning and expression analysis of human bleomycin hydrolase, a cysteine proteinase involved in chemotherapy resistance. in Cancer research 1996 (PubMed)
    Show all 3 references for ABIN1881112

  3. Human Polyclonal BLMH Primary Antibody for WB - ABIN1881113 : Brömme, Rossi, Smeekens, Anderson, Payan: Human bleomycin hydrolase: molecular cloning, sequencing, functional expression, and enzymatic characterization. in Biochemistry 1996 (PubMed)
    Show all 3 references for ABIN1881113

  4. Human Polyclonal BLMH Primary Antibody for ELISA, WB - ABIN560067 : Englert, Kliment, Ramsgaard, Milutinovic, Crum, Tobolewski, Oury: Paradoxical function for the receptor for advanced glycation end products in mouse models of pulmonary fibrosis. in International journal of clinical and experimental pathology 2011 (PubMed)
    Show all 2 references for ABIN560067

  5. Chicken Polyclonal BLMH Primary Antibody for WB - ABIN2786515 : de Haas, Zwart, Meijer, Nuver, Boezen, Suurmeijer, Hoekstra, van der Steege, Sleijfer, Gietema: Variation in bleomycin hydrolase gene is associated with reduced survival after chemotherapy for testicular germ cell cancer. in Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008 (PubMed)

More Antibodies against BLMH Interaction Partners

Mouse (Murine) Bleomycin Hydrolase (BLMH) interaction partners

  1. Blmh interacts with diverse cellular processes--lipoprotein, amino acid and protein, carbohydrate, and energy metabolisms, detoxification, antioxidant defenses--that are essential for normal kidney homeostasis.

  2. Bleomycin hydrolase protects against neurodegeneration associated with elevated homocysteine thiolactone levels in hyperhomocysteinemia and Alzheimer's disease.

  3. bleomycin hydrolase functions as an MHC class I epitope-processing protease

  4. BH does not play a major role either in generating or destroying class I major histocompatibility antigen (MHC)-presented peptides that bind to the MHC in living cells. These results point to redundant functions between peptidases.

Human Bleomycin Hydrolase (BLMH) interaction partners

  1. Bleomycin hydrolase downregulation in lesional skin of adult atopic dermatitis patients is independent of filaggrin (show FLG Antibodies) gene mutations

  2. This study findings suggest that Blmh interacts with diverse cellular processes from energy metabolism and anti-oxidative defenses to cell cycle, cytoskeleton dynamics, and synaptic plasticity essential for normal brain homeostasis.

  3. We also detected significant association between XRCC1 (show XRCC1 Antibodies), XRCC3 (show XRCC3 Antibodies), and BLHX polymorphisms and a high frequency of chromosomal damage

  4. The caspase (show CASP3 Antibodies)-dependent cleavage of BLH was confirmed by cleavage of partly-purified human bleomycin hydrolase with caspase-3 (show CASP3 Antibodies).

  5. present study suggests that our new method can detect novel genes of interest and that BLMH is a suppressor gene in HCC (show FAM126A Antibodies)

  6. This first report on BLMH carrier status in Tunisia shows o association between carrying the BLMH-G genotype and Alzheimer's disease in epsilon4 negative or positive subjects.

  7. Cysteine proteases bleomycin hydrolase and cathepsin Z (show CTSZ Antibodies) mediate N-terminal proteolysis and toxicity of mutant huntingtin (show HTT Antibodies).

  8. BH activity and expression were markedly decreased in AD lesional skin, suggesting a defect of the filaggrin (show FLG Antibodies) degradation pathway in AD.

  9. The homozygous variant G/G of BLMH gene SNP A1450G is associated with reduced survival and higher prevalence of early relapses in TC patients treated with bleomycin-containing chemotherapy.

BLMH Antigen Profile

Protein Summary

Bleomycin hydrolase (BMH) is a cytoplasmic cysteine peptidase that is highly conserved through evolution\; however, the only known activity of the enzyme is metabolic inactivation of the glycopeptide bleomycin (BLM), an essential component of combination chemotherapy regimens for cancer. The protein contains the signature active site residues of the cysteine protease papain superfamily.

Gene names and symbols associated with BLMH

  • bleomycin hydrolase (BLMH) antibody
  • Bleomycin hydrolase (pepC) antibody
  • bleomycin hydrolase (AaeL_AAEL008041) antibody
  • Bleomycin hydrolase (Apre_0140) antibody
  • Bleomycin hydrolase (Apar_0899) antibody
  • Bleomycin hydrolase (Smon_1289) antibody
  • Bleomycin hydrolase (Kfla_1242) antibody
  • Bleomycin hydrolase (Snas_3912) antibody
  • bleomycin hydrolase (BLJ_1941) antibody
  • Bleomycin hydrolase (Olsu_1085) antibody
  • bleomycin hydrolase (PGTDC60_0106) antibody
  • bleomycin hydrolase (Blmh) antibody
  • bleomycin hydrolase (blmh) antibody
  • AI035728 antibody
  • BH antibody
  • BMH antibody
  • wu:fb13c01 antibody
  • zgc:66261 antibody

Protein level used designations for BLMH

Bleomycin hydrolase , bleomycin hydrolase , BLM hydrolase , BH , BMH , aminopeptidase H

GENE ID SPECIES
100072223 Equus caballus
5300178 Flavobacterium psychrophilum JIP02/86
5569945 Aedes aegypti
8396891 Anaerococcus prevotii DSM 20548
8413765 Atopobium parvulum DSM 20469
8601031 Streptobacillus moniliformis DSM 12112
8717835 Kribbella flavida DSM 17836
8885112 Stackebrandtia nassauensis DSM 44728
9190601 Bifidobacterium longum subsp. longum JDM301
9499925 Olsenella uli DSM 7084
10722336 Porphyromonas gingivalis TDC60
104184 Mus musculus
287552 Rattus norvegicus
336541 Danio rerio
734349 Xenopus laevis
395996 Gallus gallus
642 Homo sapiens
480635 Canis lupus familiaris
504483 Bos taurus
100009580 Oryctolagus cuniculus
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