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BVES encodes a member of the POP family of proteins containing three putative transmembrane domains. Additionally we are shipping Blood Vessel Epicardial Substance Proteins (7) and Blood Vessel Epicardial Substance Kits (1) and many more products for this protein.
Showing 10 out of 47 products:
Human Polyclonal BVES Primary Antibody for EIA, WB - ABIN950694
Kim, Jang, Haam, Kang, Kim, Kim, Noh, Song, Cho, Jeong, Kim, Yoo, Kim: Frequent silencing of popeye domain-containing genes, BVES and POPDC3, is associated with promoter hypermethylation in gastric cancer. in Carcinogenesis 2010
Show all 3 references for ABIN950694
Human Polyclonal BVES Primary Antibody for IHC (p), WB - ABIN656934
Sulem, Gudbjartsson, Rafnar, Holm, Olafsdottir, Olafsdottir, Jonsson, Alexandersen, Feenstra, Boyd, Aben, Verbeek, Roeleveld, Jonasdottir, Styrkarsdottir, Steinthorsdottir: Genome-wide association study identifies sequence variants on 6q21 associated with age at menarche. in Nature genetics 2010
Show all 2 references for ABIN656934
a loss of zBves affects the proteins involved in the pathway of the PAR (show AFG3L2 Antibodies) junctional complex, especially aPKC, and both aPKC and Bves are indispensable to claudin expression.
Forced expression of POPDC1(S201F) in a murine cardiac muscle cell line (HL-1 (show ASGR1 Antibodies)) increased hyperpolarization and upstroke velocity of the action potential
These results suggest that down-regulation of BVES in hepatocellular carcinoma induces epithelial-mesenchymal transition, thus promoting invasion and metastasis in HCC (show FAM126A Antibodies) cells.
Coding sequence and splice junctions of BVES were sequenced in 114 unrelated patients with Tetralogy of Fallot and 400 unrelated healthy individuals.Four novel BVES mutations were identified in patients with TOF (show FEZF2 Antibodies) but not in the 400 controls.
Popdc1 (Bves) mod (show POPDC2 Antibodies)ulates cardiac pacemaker activity in response (show KCNAB2 Antibodies) to str (show KCNK2 Antibodies)ess and displays high expression levels in the sinus node. The Popeye domain acts as a high-affinity cAMP binding domain and Popdc proteins interact with the ion channel TREK-1.
Low Bves expression is associated with gastric cancer progression.
BVES was found to be underexpressed in all stages of colorectal carcinoma and in adenomatous polyps, indicating its suppression occurs early in transformation.
Bves expression and localization can regulate RhoA (show RHOA Antibodies) and ZONAB/DbpA (show CSDA Antibodies) activity.
Data suggest that POPDC gene expression is modified in end-stage heart failure in humans in a manner suggesting regulatory and/or functional differences between the three family members and that POPDC1 is particularly susceptible to this condition.
Frequent silencing of BVES is associated with promoter hypermethylation in gastric cancer.
Methylation of BVES was present in 80% of NSCLC tissues but only 14% of noncancerous tissues.
Bves and NDRG4 (show NDRG4 Antibodies) regulate directional epicardial cell migration through autocrine extracellular matrix deposition.
The results indicate that Popdc1 is a caveolae-associated protein important for the preservation of caveolae structural and functional integrity and for heart protection.
Popdc1 and Popdc2 (show POPDC2 Antibodies) proteins interact with the potassium channel (show KCNAB2 Antibodies) TREK-1 (show KCNK2 Antibodies), which leads to increased cell surface expression and enhanced current density
cell surface Bves/Pop1A is composed of an extracellular amino terminus, three transmembrane domains, and a cytoplasmic carboxyl terminus, which regulates cellular distribution of Bves/Pop1A during coronary vessel development
Bves directly interacts with GEFT and is a novel regulator of the Rac1 and Cdc42 (show CDC42 Antibodies) signaling cascades.
This gene encodes a member of the POP family of proteins containing three putative transmembrane domains. This gene is expressed in cardiac and skeletal muscle and may play an important role in development of these tissues. The mouse ortholog may be involved in the regeneration of adult skeletal muscle and may act as a cell adhesion molecule in coronary vasculogenesis. Three transcript variants encoding the same protein have been found for this gene.
popeye domain containing 1
, popeye domain-containing protein 1
, blood vessel epicardial substance
, Popeye domain-containing protein 1
, Popeye protein 1
, blood vessel epicardial substance-like
, popeye protein 1
, popeye 1
, popeye domain-containing 1
, POP1C protein
, popeye domain containing protein 1