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Bol, Boule-Like (Drosophila) Proteins (BOLL)

BOLL belongs to the DAZ gene family required for germ cell development. Additionally we are shipping BOLL Antibodies (70) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
BOLL 66037 Q8N9W6
BOLL 75388 Q924M5
Rat BOLL BOLL 501143  
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Top BOLL Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Macaca fascicularis His tag   1 mg Log in to see 56 to 66 Days
$2,744.50
Details

BOLL Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Bol, Boule-Like (Drosophila) (BOLL) Interaction Partners

Human Bol, Boule-Like (Drosophila) (BOLL) interaction partners

  1. Our study demonstrated an oncogenic role of BOLL in CRC (show CALR Proteins) despite tumor-specific promoter hypermethylation.

  2. demonstrate that Boll is also transiently expressed during oogenesis in the fetal mouse ovary, but is simultaneously co-expressed within the same germ cells as Dazl (show DAZL Proteins)

  3. Assessing the expression of both CDY1 (show CDY2A Proteins) and BOULE by qualitative RT-PCR is a sensitive and feasible test for predicting the presence of sperm cells in testicular tissue biopsies.

  4. expression of spermatogenic phenotypes of partial AZFc deletions is independent of the variations in DAZL and BOULE in the Han population

  5. BOULE may encode a key conserved switch that regulates progression of germ cells through meiosis in men.

  6. Role in spermatogenesis. Decreased DAZ proteins in spermatogenic failure may be due to germ cell loss. Transcription of BOULE, DAZL, and DAZ not altered in degrees of spermatogenic failure. No increase of DAZL or BOULE found in DAZ deletion.

  7. Major group of infertile men with meiotic arrest lack BOULE protein and its putative target, CDC25A (show CDC25A Proteins) expression. Spermatogenic failure may arise from factor(s) upstream of BOULE possibly involved in regulating transcription and/or translation of BOULE.

  8. BOULE coding sequence mutations are not an important factor in the aetiology of azoospermia.

  9. mutations in BOULE can be eliminated as a major cause of impaired spermatogenesis.

  10. Among the three BOULE isoforms, B2 might have the major role for meiotic completion.

Cow (Bovine) Bol, Boule-Like (Drosophila) (BOLL) interaction partners

  1. The b-boule gene is predicted to encode a polypeptide of 295 amino acids with an RNP (show RNPC3 Proteins)-type RNA recognition domain. Tertiary structure analysis shows that b-boule binds specifically to polypyrimidine RNAs.

Mouse (Murine) Bol, Boule-Like (Drosophila) (BOLL) interaction partners

  1. These results showed that IGF1 regulated the expression of BOULE and CDC25A mRNAs via ERK1/2 signaling and in T-independent pathway during spermatogenesis in the adult mouse testes.

  2. demonstrate that Boll is also transiently expressed during oogenesis in the fetal mouse ovary, but is simultaneously co-expressed within the same germ cells as Dazl (show DAZL Proteins)

  3. Expression of key regulators of spermiogenesis was unaffected in Boule(-/-) mice, suggesting that Boule regulates germ-cell differentiation through a novel pathway.

BOLL Protein Profile

Protein Summary

This gene belongs to the DAZ gene family required for germ cell development. It encodes an RNA-binding protein which is more similar to Drosophila Boule than to human proteins encoded by genes DAZ (deleted in azoospermia) or DAZL (deleted in azoospermia-like). Loss of this gene function results in the absence of sperm in semen (azoospermia). Histological studies demonstrated that the primary defect is at the meiotic G2/M transition. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Gene names and symbols associated with BOLL

  • boule (LOC100155042)
  • bol, boule-like (Drosophila) (BOLL)
  • boule-like (LOC100341687)
  • protein boule-like (LOC100447397)
  • protein boule-like (LOC100475887)
  • bol, boule-like (Drosophila) (Boll)
  • 4930554P13Rik protein
  • 4930597B14Rik protein
  • BOULE protein
  • RGD1559527 protein

Protein level used designations for BOLL

protein boule-like , boule-like , boule

GENE ID SPECIES
100155042 Sus scrofa
698402 Macaca mulatta
100341687 Oryctolagus cuniculus
100447397 Pongo abelii
100475887 Ailuropoda melanoleuca
66037 Homo sapiens
527841 Bos taurus
75388 Mus musculus
501143 Rattus norvegicus
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