anti-Bone Morphogenetic Protein 15 (BMP15) Antibodies

may regulate granulosa cell growth and ovarian follicle formation [RGD, Feb 2006].. Additionally we are shipping BMP15 Kits (33) and BMP15 Proteins (10) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
BMP15 9210 O95972
BMP15 12155 Q9Z0L4
BMP15 59302  
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Top anti-BMP15 Antibodies at antibodies-online.com

Showing 10 out of 83 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p) 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of anti-Bmp15 Antibody (N-term) (ABIN388449) in HL60 cell line lysate (35 µg/lane). Bmp15(arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of BMP15 Antibody (Center) (ABIN388450) in CEM cell line lysates (35 µg/lane). BMP15 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human prostata carcinoma tissue reacted with BMP15 antibody (Center) (ABIN388450), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB   100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated IHC, ELISA 0.1 mg Log in to see 2 to 3 Days
$340.00
Details
Human Rabbit Un-conjugated EIA, IF, WB   0.1 mg Log in to see 12 to 15 Days
$375.38
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 16 Days
$175.80
Details
Human Rabbit Un-conjugated IHC (p) Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Immunohistochemistry-Paraffin: BMP-15/GDF-9B Antibody [NBP2-14888] - Paraffin-embedded NCI-N87 xenograft. Western Blot: BMP-15/GDF-9B Antibody [NBP2-14888] - A: H1299. 0.1 mL Log in to see 8 to 11 Days
$447.56
Details

BMP15 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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More Antibodies against BMP15 Interaction Partners

Zebrafish Bone Morphogenetic Protein 15 (BMP15) interaction partners

  1. Females deficient in Bmp15 begin development normally but switch sex during the mid- to late- juvenile stage, and become fertile males.

  2. Incubation with antiserum increased oocyte maturaation whereas incubation with recombinant human BMP-15 suppressed human chorionic gonadotropin-induced oocyte maturation.

  3. BMP-15 modulates follicular growth and prevents premature oocyte maturation in zebrafish.

  4. These findings suggest that activin-A (show INHBA Antibodies), TGF-beta1 (show TGFB1 Antibodies), and BMP-15 may target common gene(s) to regulate oocyte maturation.

Human Bone Morphogenetic Protein 15 (BMP15) interaction partners

  1. Mutations in BMP15 associated with primary ovarian insufficiency reduce mature protein production, activity, or synergy with GDF9 (show GDF9 Antibodies).

  2. Human GDF9 (show GDF9 Antibodies) and BMP15 act synergistically to stimulate granulosa cell proliferation, a response that also involves species-specific non-SMAD (show SMAD1 Antibodies) signalling pathways.

  3. GDF9 (show GDF9 Antibodies) c.169G>T (D57Y), c.546G>A (rs1049127), and BMP15 rs79377927 (788_789insTCT) were associated with premature ovarian failure in the Chinese Hui population.

  4. BMP15 supplementation differentially modulates reductive metabolism and mitochondrial localization within the oocyte.

  5. results support a model of activation for human GDF9 (show GDF9 Antibodies) dependent on cumulin formation through heterodimerization with BMP15. Oocyte-secreted cumulin is likely to be a central regulator of fertility in mono-ovular mammals.

  6. GDF9 (show GDF9 Antibodies) and BMP15 expression is reduced in primordial, primary, and secondary follicles in ovarian tissues of PCOS patients.

  7. The results showed no direct association between BMP15-9G or 852T and the development of premature ovarian failure (POF (show POF1B Antibodies)). Women with the 538A mutation are up to five times more likely to develop POF (show POF1B Antibodies). The 788insTCT polymorphism had low biological impact.

  8. the BMP15 c.-9G allele is related to BMP15 increased transcription, supporting c.-9C>G as a causal agent of premature ovarian failure

  9. BMP15 polymorphism is not associated with ovarian reserve.

  10. BMP15 is a critical regulator of folliculogenesis and granulosa cell activities. Variations in BMP15 gene dosage have a relevant influence on ovarian function and can account for several defects of female fertility.

Mouse (Murine) Bone Morphogenetic Protein 15 (BMP15) interaction partners

  1. these data provide evidence that the preovulatory LH surge leads to upregulation of several forms of BMP15 protein secreted by the oocyte for putative sequestration and/or interaction with ovarian follicular somatic cells.

  2. Data show that Rac1 induced nuclear import of STAT3 (show STAT3 Antibodies) by physical binding, and nuclear STAT3 (show STAT3 Antibodies) directly activated the transcription of essential oocyte-specific genes, including Jagged1 (show JAG1 Antibodies), GDF9 (show GDF9 Antibodies) and BMP15.

  3. results support a model of activation for human GDF9 (show GDF9 Antibodies) dependent on cumulin formation through heterodimerization with BMP15. Oocyte-secreted cumulin is likely to be a central regulator of fertility in mono-ovular mammals.

  4. modified oocyte glycoproteins alter GDF9 (show GDF9 Antibodies):BMP15 expression modifying follicle development resulting in the generation of more follicles

  5. findings that GDF9 (show GDF9 Antibodies):BMP15 heterodimers are the most bioactive ligands in mice and humans compared with homodimers explain many puzzling genetic and physiological data and have important implications for improving female fertility in mammals

  6. show that purified mature regions of GDF9 (show GDF9 Antibodies) and BMP15 synergistically interact in a specific manner which is not dependent on the presence of a pro-region.

  7. Integral role of GDF-9 (show GDF9 Antibodies) and BMP-15 in ovarian function.

  8. oocyte-derived GDF9 (show GDF9 Antibodies) and Bmp15 coordinate to promote the development of cumulus cells E2 and oocyte-derived paracrine factors GDF9 (show GDF9 Antibodies) and bone morphogenetic protein 15 coordinate to promote the development of cumulus cells

  9. The results showed that both GDF-9 (show GDF9 Antibodies) and BMP-15 were detectable in oocytes from primary follicles onward, besides, BMP-15 also presented in granulosa cells (GCs (show UGCG Antibodies)) and follicular follicle of mature follicles in mouse

  10. bone morphogenetic protein-15 could play a physiological role in the monotropic rise of FSH (show BRD2 Antibodies) secretion by the pituitary during the estrous and menstrual cycle

Pig (Porcine) Bone Morphogenetic Protein 15 (BMP15) interaction partners

  1. These results show that GDF9 (show GDF9 Antibodies) and BMP15 participate in cumulus expansion and that they stimulate MPF (show MSLN Antibodies) and MAPK (show MAPK1 Antibodies) activities in porcine oocytes during in vitro maturation.

  2. Report temporal regulation of BMP15 mRNA expression in the oocyte, granulosa and theca cells of developing preovulatory follicles in the pig.

Cow (Bovine) Bone Morphogenetic Protein 15 (BMP15) interaction partners

  1. Amphiregulin (show AREG Antibodies) co-operates with bone morphogenetic protein 15 to increase bovine oocyte developmental competence.

  2. In conclusion, BMP-15 should be considered as a potential genetic marker for sperm quality, based on its association with fresh sperm motility.

  3. BMP15 and FGF10 (show FGF10 Antibodies) stimulate expansion of in cumulus-oocyte complexes by driving glucose metabolism toward hyaluronic acid production and controlling gene expression in the ovulatory cascade.

  4. Immunization against GDF9 (show GDF9 Antibodies) and BMP15, alone or together, altered follicular development and ovulation rate in cattle.

  5. BMP15 expression in the oocytes of calf and adult ovaries was not significantly different. BMP15 transcripts were detected in ovarian tissues, but were not detected in any other tissues examined by RT-PCR.

  6. Maternal BMP15 transcripts persisted during oocyte in vitro maturation and fertilization and in preimplantation embryo until the five- to eight-cell or morula stage, but transcription was not reactivated at the time of embryonic genome activation.

  7. polymorphism in the bovine bone morphogenetic protein 15 (BMP15) gene

Goat Bone Morphogenetic Protein 15 (BMP15) interaction partners

  1. Studied six SNPs in goat BMPR1B (show BMPR1B Antibodies), BMP15, and GDF9 (show GDF9 Antibodies) for their association with litter size in seven breeds of Indian goats. Found no association between these SNPs and prolificacy in the breeds investigated.

  2. Expression of BMP15 (p < 0.01) and GDF9 (show GDF9 Antibodies) (p < 0.05) mRNAs was more abundant in the small than the large antral follicles of Black Bengal goat.

  3. Mutations in BMP15 gene has been associated with prolificacy.

  4. The expression level of BMP15 mRNA in follicle of Lezhi black goat was 5.72-fold greater than that in Tibetan goat.

BMP15 Antigen Profile

Protein Summary

may regulate granulosa cell growth and ovarian follicle formation

Gene names and symbols associated with BMP15

  • bone morphogenetic protein 15 (BMP15) antibody
  • bone morphogenetic protein 15 (bmp15) antibody
  • bone morphogenetic protein 15 (Bmp15) antibody
  • bone morphogenetic protein 15-like (LOC100856301) antibody
  • AU015375 antibody
  • AU018861 antibody
  • AU021453 antibody
  • BMP-15 antibody
  • BMP15 antibody
  • C86824 antibody
  • C87336 antibody
  • fi35a05 antibody
  • Gdf-9b antibody
  • GDF9B antibody
  • ODG2 antibody
  • POF4 antibody
  • wu:fi35a05 antibody

Protein level used designations for BMP15

bone morphogenetic protein 15 , bone morphogenetic protein 15-like , BMP-15 , GDF-9B , growth/differentiation factor 9B , growth differentiation factor-9B , BMP-15/GDF-9B , bone morphogenetic protein 15 proprotein , growth differentiation factor 9B

GENE ID SPECIES
100052461 Equus caballus
334183 Danio rerio
473873 Pan troglodytes
491885 Canis lupus familiaris
695457 Macaca mulatta
100301545 Oryctolagus cuniculus
100306941 Felis catus
100441790 Pongo abelii
100583339 Nomascus leucogenys
9210 Homo sapiens
12155 Mus musculus
59302 Rattus norvegicus
428697 Gallus gallus
448811 Sus scrofa
353351 Bos taurus
100355411 Oryctolagus cuniculus
100732890 Cavia porcellus
100141303 Ovis aries
100861233 Capra hircus
100856301 Canis lupus familiaris
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