You are viewing an incomplete version of our website. Please click to reload the website as full version.

Bone Morphogenetic Protein Receptor, Type IA Proteins (BMPR1A)

The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. Additionally we are shipping BMPR1A Antibodies (6) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
BMPR1A 657 P36894
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top BMPR1A Proteins at antibodies-online.com

Showing 1 out of 2 products:

Catalog No. Origin Source Conjugate Quantity Supplier Delivery Price Details
HOST_Baculovirus infected Insect Cells Human GST tag 5 μg Log in to see 10 to 12 Days
$322.08
Details

BMPR1A Proteins by Origin and Source

Origin Expressed in Conjugate
Human

More Proteins for Bone Morphogenetic Protein Receptor, Type IA (BMPR1A) Interaction Partners

Human Bone Morphogenetic Protein Receptor, Type IA (BMPR1A) interaction partners

  1. Duplication of 10q22.3-q23.3 encompassing BMPR1A gene is associated with congenital heart disease, microcephaly, and mild intellectual disability

  2. Authors analyzed human databases from TCGA and survival data from microarrays to confirm BMPR1a tumor promoting functions, and found that high BMPR1a gene expression correlates with decreased survival regardless of molecular breast cancer subtype.

  3. About half of BMPR1A-related polyps displayed loss of heterozygosity, predominantly in the epithelial compartment, compatible with BMPR1A acting as a tumour suppressor gene.

  4. Results support a novel role for miR (show MLXIP Proteins)-885-3p in tumor angiogenesis by targeting BMPR1A, which regulates a proangiogenic factor.

  5. Decreased expression of BMPR1A was associated malignant gallbladder lesions.

  6. High BMPR1A expression is associated with glioma tumorigenesis.

  7. Data show that USP15 (show USP15 Proteins) enhances BMP-induced phosphorylation of SMAD1 (show GARS Proteins) by interacting with and deubiquitylating ALK3.

  8. This is the first case report to document coding exon 3 duplication in the BMPR1A gene in a patient with juvenile polyposis syndrome.

  9. results provide evidence that HFE (show HFE Proteins) induces hepcidin (show HAMP Proteins) expression via the BMP pathway: HFE (show HFE Proteins) interacts with ALK3 to stabilize ALK3 protein and increase ALK3 expression at the cell surface.

  10. BMP15 (show BMP15 Proteins) down-regulates StAR expression and decreases progesterone production in human granulosa cells, likely via ALK3-mediated SMAD1 (show GARS Proteins)/5/8 signaling.

BMPR1A Protein Profile

Protein Summary

The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.

Gene names and symbols associated with BMPR1A

  • bone morphogenetic protein receptor, type IA (BMPR1A)
  • bone morphogenetic protein receptor, type IA (LOC100223148)
  • bone morphogenetic protein receptor, type IA (bmpr1a)
  • 10q23del protein
  • ACVRLK3 protein
  • ALK3 protein
  • BMPR1A protein
  • CD292 protein
  • SKR5 protein

Protein level used designations for BMPR1A

ALK-3 , BMP type-1A receptor , BMPR-1A , activin A receptor, type II-like kinase 3 , activin receptor-like kinase 3 , bone morphogenetic protein receptor type-1A , serine/threonine-protein kinase receptor R5 , bone morphogenetic protein receptor, type IA , bone morphogenetic protein receptor type-1A-like

GENE ID SPECIES
657 Homo sapiens
696898 Macaca mulatta
100064367 Equus caballus
100077843 Ornithorhynchus anatinus
100153524 Sus scrofa
450572 Pan troglodytes
100026839 Monodelphis domestica
100223148 Taeniopygia guttata
100350518 Oryctolagus cuniculus
100402757 Callithrix jacchus
100450136 Pongo abelii
100472999 Ailuropoda melanoleuca
100561841 Anolis carolinensis
100583682 Nomascus leucogenys
Did you look for something else?