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anti-Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2) Antibodies

BMPR2 encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. Additionally we are shipping BMPR2 Kits (20) and BMPR2 Proteins (16) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
BMPR2 659 Q13873
BMPR2 12168 O35607
BMPR2 140590  
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Top anti-BMPR2 Antibodies at antibodies-online.com

Showing 10 out of 115 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of anti-BMPR2 Pab (ABIN388741) in mouse heart tissue lysate. BMPR2 (arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence. Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with BMPR2 antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated IHC, ELISA, WB Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 ng), Blue: Antigen (100 ng) Figure 2: Immunohistochemical analysis of paraffin-embedded breast cancer tissues (left) and tonsil tissues (right) using BMPR2 mouse mAb with DAB staining. 100 μL Log in to see 3 to 4 Days
$430.10
Details
Human Mouse Un-conjugated ICC, IHC, ELISA, WB Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 ng), Blue: Antigen (100 ng) Figure 2: Immunofluorescence analysis of Eca109 cells using BMPR2 mouse mAb (green) . Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin. 100 μL Log in to see 3 to 4 Days
$430.10
Details
Human Mouse Un-conjugated IF, WB Western blot analysis of BMPR-II on mouse cerebrum lysate. Lane 1: 1:250, lane 2 :1:500, lane 3: 1:1000 dilution of anti-BMPR-II antibody 50 μg Log in to see 5 to 6 Days
$205.42
Details
Human Rabbit Un-conjugated FACS, IHC, WB 100 μL Log in to see 2 to 3 Days
$304.50
Details
Human Rabbit Un-conjugated WB WB Image Sample (30 ug of whole cell lysate) A:NIH-3T3 7.5% SDS PAGE antibody diluted at 1:1000 WB Image Sample(30 μg of whole cell lysate) A:H1299 B:Raji , 7.5% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Mouse Un-conjugated EIA, IHC (p), WB 0.1 mL Log in to see 6 to 8 Days
$423.50
Details
Human Mouse Un-conjugated EIA, IF, IHC (p), WB 0.1 mL Log in to see 6 to 8 Days
$423.50
Details
Human Mouse Un-conjugated IHC (p), ELISA, WB Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Log in to see 8 to 10 Days
$451.00
Details

BMPR2 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-BMPR2 Antibodies

  1. Human Polyclonal BMPR2 Primary Antibody for FACS, IHC (p) - ABIN388741 : Pouliot, Blais, Labrie: Overexpression of a dominant negative type II bone morphogenetic protein receptor inhibits the growth of human breast cancer cells. in Cancer research 2003 (PubMed)
    Show all 9 references for ABIN388741

  2. Human Monoclonal BMPR2 Primary Antibody for IF, WB - ABIN968806 : , Lane, Machado, Pauciulo, Thomson, Phillips, Loyd, Nichols, Trembath: Heterozygous germline mutations in BMPR2, encoding a TGF-beta receptor, cause familial primary pulmonary hypertension. in Nature genetics 2000 (PubMed)
    Show all 3 references for ABIN968806

  3. Human Monoclonal BMPR2 Primary Antibody for IHC, ELISA - ABIN968987 : Rosenzweig, Morse, Knowles, Chada, Khan, Roberts, McElroy, Juskiw, Mallory, Rich, Diamond, Barst: Clinical implications of determining BMPR2 mutation status in a large cohort of children and adults with pulmonary arterial hypertension. in The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2008 (PubMed)
    Show all 2 references for ABIN968987

  4. Human Monoclonal BMPR2 Primary Antibody for EIA, IHC (p) - ABIN1105548 : Phillips, Poling, Phillips, Stanton, Austin, Cogan, Wheeler, Yu, Newman, Dietz, Loyd: Synergistic heterozygosity for TGFbeta1 SNPs and BMPR2 mutations modulates the age at diagnosis and penetrance of familial pulmonary arterial hypertension. in Genetics in medicine : official journal of the American College of Medical Genetics 2008 (PubMed)
    Show all 2 references for ABIN1105548

More Antibodies against BMPR2 Interaction Partners

Zebrafish Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2) interaction partners

  1. bmpr2b mediates BMP signaling and is required to establish left-right asymmetry.

Human Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2) interaction partners

  1. the data in the present study support the notion that the expression levels and plasma membrane levels of BMPRII are determined by two molecular processes-translational regulation of protein synthesis (which provides the major contribution) and endocytosis/degradation (mild modulatory effect).

  2. In a group of pulmonary arterial hypertension patients, 25.4% harboured heterozygous mutation in the BMPR2 gene.

  3. An up-regulated expression of BMP-4 (show BMP4 Antibodies) and BMPR-II was observed in the peripheral blood of breast cancer patients especially in the advanced-stage of the disease. Moreover, BMP-4 (show BMP4 Antibodies) and BMPR-II expressions were found to be correlated

  4. establish the feasibility of combining NELL-1 (show NELL1 Antibodies) with BMP2 (show BMP2 Antibodies) to improve clinical bone regeneration and provide mechanistic insight into canonical Wnt (show WNT2 Antibodies) pathway activity during NELL-1 (show NELL1 Antibodies) and BMP2 (show BMP2 Antibodies) osteogenesis

  5. Raf (show RAF1 Antibodies) family members and ERK1/2 (show MAPK1/3 Antibodies) were constitutively activated after BMPR2 knockdown

  6. miR (show MLXIP Antibodies)-153 is a mechano-sensitive miRNA that regulates osteoblast differentiation by directly targeting BMPR2, and that therapeutic inhibition of miR (show MLXIP Antibodies)-153 may be an efficient anabolic strategy for skeletal disorders caused by pathological mechanical loading.

  7. BMP-2 (show BMP2 Antibodies) and -4 are produced by vascular smooth muscle cells in atherosclerotic lesions and induce monocyte chemotaxis through direct BMPRII activation

  8. study shows for the first time that in the regulatory region of the BMPR2 gene the promoter may be important for pulmonary arterial hypertension penetrance

  9. Correlations between C23 (show NCL Antibodies), BMPRII expression and prognosis of gastric cancer patients.

  10. local gene transfection can up-regulate the expression of osteogenic mediators (BMP-2 (show BMP2 Antibodies) and TGF-beta1 (show TGFB1 Antibodies)), which may promote cell differentiation and proliferation and stimulate extracellular matrix synthesis and new bone formation in distraction gap.

Mouse (Murine) Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2) interaction partners

  1. Deleting Bmpr2 in mouse skeletal progenitor cells impaired activin (show Actbeta Antibodies) signaling resulting in an increased bone formation rate and high bone mass.

  2. The findings suggest that the mutant ALK2 (show ACRV1 Antibodies) related to Fibrodysplasia ossificans progressiva is enhanced by bone morphogenetic protein type II receptors via the T203-regulated phosphorylation of ALK2 (show ACRV1 Antibodies).

  3. BMPR2 has tumor suppressive functions in the stroma by regulating inflammation.

  4. Serotonin can increase ERalpha (show ESR1 Antibodies) expression in human pulmonary arterial smooth muscle cells and antagonism of oestrogen receptor alpha reverses serotonin-dependent PH in the mouse and increases bone morphogenetic protein receptor type 2 expression

  5. BMPR2 preserves mitochondrial function and DNA during reoxygenation to promote endothelial cell survival and reverse pulmonary hypertension.

  6. Members of the miR-17 family influence gastrulation by suppressing Bmpr2 expression at the primitive streak.

  7. Bmp4 (show BMP4 Antibodies), Bmp7 (show BMP7 Antibodies) and bmpr2 signalling regulates the pre-implantation development of extra-embryonic cell lineages in the mouse embryo

  8. Mutations in BMPR2 underlie most heritable cases and a small proportion of sporadic cases of idiopathic pulmonary arterial hypertension.

  9. BMP9 (show GDF2 Antibodies) is identified as the preferred ligand for preventing apoptosis and enhancing monolayer integrity in endothelial cells from subjects with pulmonary arterial hypertension who bear mutations in the gene encoding BMPR2.

  10. These data suggest that heterozygous null BMPR2 mutations promote SRC (show SRC Antibodies)-dependent caveolar trafficking defects in PECs and that this may contribute to pulmonary endothelial barrier dysfunction in Hereditary pulmonary arterial hypertension patients

Pig (Porcine) Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2) interaction partners

  1. Report temporal regulation of BMPR2 mRNA expression in the oocyte, granulosa and theca cells of developing preovulatory follicles in the pig.

  2. Losartan therapy was associated with persistent overexpressions of ANG II (show AGT Antibodies), AT2 (show AGTR2 Antibodies), ET-1 (show EDN1 Antibodies), ETB (show EDNRB Antibodies), and angiopoietin-1 (show ANGPT1 Antibodies) and with a return to normal of the BMPR-2 expression.

Cow (Bovine) Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2) interaction partners

  1. Stimulation of BMPRII promotes normal pulmonary artery endothelial cell function by activating eNOS (show NOS3 Antibodies).

BMPR2 Antigen Profile

Protein Summary

This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease.

Gene names and symbols associated with BMPR2

  • bone morphogenetic protein receptor, type II (serine/threonine kinase) (BMPR2) antibody
  • bone morphogenetic protein receptor, type II b (serine/threonine kinase) (bmpr2b) antibody
  • bone morphogenetic protein receptor, type II (serine/threonine kinase) (Bmpr2) antibody
  • 2610024H22Rik antibody
  • AL117858 antibody
  • AW546137 antibody
  • BB189135 antibody
  • BMP-2 antibody
  • BMPR-2 antibody
  • Bmpr-II antibody
  • BMPR3 antibody
  • bmprii antibody
  • BMR2 antibody
  • BRK-3 antibody
  • Gm20272 antibody
  • PPH1 antibody
  • T-ALK antibody

Protein level used designations for BMPR2

bone morphogenetic protein receptor type II , bone morphogenetic protein receptor type-2 , bone morphogenetic protein receptor type II b , BMP type II receptor , BMP type-2 receptor , BMPR-2 , type II activin receptor-like kinase , type II receptor for bone morphogenetic protein-4 , bone morphogenic protein receptor, type II (serine/threonine kinase) , bone morphogenic protein receptor type 2

GENE ID SPECIES
459885 Pan troglodytes
555655 Danio rerio
659 Homo sapiens
12168 Mus musculus
140590 Rattus norvegicus
374147 Gallus gallus
100127483 Sus scrofa
407127 Bos taurus
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