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Bone Morphogenetic Protein Receptor 1A Proteins (BMPR1A)

The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. Additionally we are shipping BMPR1A Antibodies (180) and BMPR1A Kits (50) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
BMPR1A 12166 P36895
BMPR1A 657 P36894
BMPR1A 81507 Q78EA7
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Top BMPR1A Proteins at antibodies-online.com

Showing 10 out of 36 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Cells Dog Fc Tag 100 μg Log in to see 16 Days
$272.80
Details
HOST_Human Cells Human His tag,Fc Tag 100 μg Log in to see 16 Days
$272.80
Details
HOST_Human Cells Mouse His tag,Fc Tag 100 μg Log in to see 16 Days
$272.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Baculovirus infected Insect Cells Human Un-conjugated   1 mg Log in to see 2 to 3 Days
$5,223.75
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 11 to 12 Days
$246.96
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

BMPR1A Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) , ,
, ,
Human , , , , , , , ,
, , , ,
Rat (Rattus)

Top referenced BMPR1A Proteins

  1. Dog (Canine) BMPR1A Protein expressed in Human Cells - ABIN2008897 : Hoodless, Haerry, Abdollah, Stapleton, OConnor, Attisano, Wrana: MADR1, a MAD-related protein that functions in BMP2 signaling pathways. in Cell 1996 (PubMed)
    Show all 3 references for ABIN2008897

  2. Mouse (Murine) BMPR1A Protein expressed in Human Cells - ABIN2007284 : Koenig, Cook, Wolsing, Ting, Tiesman, Correa, Olson, Pecquet, Ventura, Grant: Characterization and cloning of a receptor for BMP-2 and BMP-4 from NIH 3T3 cells. in Molecular and cellular biology 1994 (PubMed)
    Show all 3 references for ABIN2007284

  3. Human BMPR1A Protein expressed in Human Cells - ABIN2002862 : Ishidou, Kitajima, Obama, Maruyama, Murata, Imamura, Yamada, ten Dijke, Miyazono, Sakou: Enhanced expression of type I receptors for bone morphogenetic proteins during bone formation. in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1996 (PubMed)
    Show all 3 references for ABIN2002862

More Proteins for Bone Morphogenetic Protein Receptor 1A (BMPR1A) Interaction Partners

Pig (Porcine) Bone Morphogenetic Protein Receptor 1A (BMPR1A) interaction partners

  1. Report temporal regulation of BMPR1a mRNA expression in the oocyte, granulosa and theca cells of developing preovulatory follicles in the pig.

Mouse (Murine) Bone Morphogenetic Protein Receptor 1A (BMPR1A) interaction partners

  1. study suggested that Bmpr-Ia and Bmpr-Ib (show BMPR1B Proteins) signaling regulates tooth formation via miR (show MLXIP Proteins)-135a.

  2. integrin alpha1beta1/BMPR IA may block BMP-2 (show BMP2 Proteins)/BMPR IA complex information and interfere with the BMP-2 (show BMP2 Proteins) signalling pathway in cells

  3. signaling via activin-like kinase 3 (ALK3/BMPR1A), a BMP type 1 receptor, is necessary for blastocyst attachment.

  4. Interactions between mechanical loading and BMP signaling through BMPR1A.

  5. Myo-endothelial progenitors with functioning Bmpr1a signalling demonstrate myogenic potential, but their main function in vivo is to inhibit intramuscular adipogenesis, both through a cell-autonomous and a cell-cell interaction mechanism.

  6. Bmpr1a is critical for the development and growth of the mandibular condyle via its effect on proliferation of prechondroblasts and chondrocyte differentiation

  7. BMP-Smad4 (show SMAD4 Proteins) signaling is required for precartilaginous mesenchymal condensation independent of Sox9 (show SOX9 Proteins) in the mouse.

  8. An essential role of finely tuned BMPRIA mediated signaling in temporomandibular joint development.

  9. Alk3 mediated Bmp signaling is important in the cascade of events that regulate the contribution of EPDCs to the AV sulcus, annulus fibrosus, and the parietal leaflets of the AV valve

  10. Anti-Mullerian hormone (show AMH Proteins) recruits BMPR-IA in immature granulosa cells

Xenopus laevis Bone Morphogenetic Protein Receptor 1A (BMPR1A) interaction partners

  1. Data show that USP15 (show USP15 Proteins) enhances BMP-induced phosphorylation of SMAD1 (show SMAD1 Proteins) by interacting with and deubiquitylating ALK3.

Human Bone Morphogenetic Protein Receptor 1A (BMPR1A) interaction partners

  1. Duplication of 10q22.3-q23.3 encompassing BMPR1A gene is associated with congenital heart disease, microcephaly, and mild intellectual disability

  2. Authors analyzed human databases from TCGA and survival data from microarrays to confirm BMPR1a tumor promoting functions, and found that high BMPR1a gene expression correlates with decreased survival regardless of molecular breast cancer subtype.

  3. About half of BMPR1A-related polyps displayed loss of heterozygosity, predominantly in the epithelial compartment, compatible with BMPR1A acting as a tumour suppressor gene.

  4. Results support a novel role for miR (show MLXIP Proteins)-885-3p in tumor angiogenesis by targeting BMPR1A, which regulates a proangiogenic factor.

  5. Decreased expression of BMPR1A was associated malignant gallbladder lesions.

  6. High BMPR1A expression is associated with glioma tumorigenesis.

  7. Data show that USP15 (show USP15 Proteins) enhances BMP-induced phosphorylation of SMAD1 (show GARS Proteins) by interacting with and deubiquitylating ALK3.

  8. This is the first case report to document coding exon 3 duplication in the BMPR1A gene in a patient with juvenile polyposis syndrome.

  9. results provide evidence that HFE (show HFE Proteins) induces hepcidin (show HAMP Proteins) expression via the BMP pathway: HFE (show HFE Proteins) interacts with ALK3 to stabilize ALK3 protein and increase ALK3 expression at the cell surface.

  10. BMP15 (show BMP15 Proteins) down-regulates StAR expression and decreases progesterone production in human granulosa cells, likely via ALK3-mediated SMAD1 (show GARS Proteins)/5/8 signaling.

BMPR1A Protein Profile

Protein Summary

The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.

Gene names and symbols associated with BMPR1A

  • bone morphogenetic protein receptor, type IA (BMPR1A)
  • bone morphogenetic protein receptor, type IA (LOC100223148)
  • bone morphogenetic protein receptor, type 1A (Bmpr1a)
  • bone morphogenetic protein receptor, type 1A (bmpr1a)
  • bone morphogenetic protein receptor, type IA (Bmpr1a)
  • 10q23del protein
  • 1110037I22Rik protein
  • ACVRLK3 protein
  • alk-3 protein
  • alk3 protein
  • AU045487 protein
  • Bmpr protein
  • BMPR-1 protein
  • BMPR-IA protein
  • BMPR1A protein
  • BRK-1 protein
  • CD292 protein
  • SKR5 protein

Protein level used designations for BMPR1A

bone morphogenetic protein receptor, type IA , bone morphogenetic protein receptor type-1A , bone morphogenetic protein receptor type-1A-like , ALK-3 , BMP type-1A receptor , BMP-2/BMP-4 receptor , BMPR-1A , SKR5 , activin receptor-like kinase 3 , serine/threonine-protein kinase receptor R5 , BMP receptor , activin A receptor, type II-like kinase 3 , bone morphogenetic protein 4 receptor , bone morphogenetic protein receptor, type 1A , bone morphogenetic protein receptor type IA , bone morphogenetic protein receptor IA , BMP receptor 1 , bone morphogenic protein receptor 1 , protein kinase

GENE ID SPECIES
450572 Pan troglodytes
696898 Macaca mulatta
100153524 Sus scrofa
100223148 Taeniopygia guttata
100402757 Callithrix jacchus
100450136 Pongo abelii
12166 Mus musculus
397712 Xenopus laevis
657 Homo sapiens
489077 Canis lupus familiaris
81507 Rattus norvegicus
100350518 Oryctolagus cuniculus
100169652 Sus scrofa
100861241 Capra hircus
404101 Bos taurus
396308 Gallus gallus
101112282 Ovis aries
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