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BASP1 encodes a membrane bound protein with several transient phosphorylation sites and PEST motifs. Additionally we are shipping BASP1 Antibodies (52) and BASP1 Kits (4) and many more products for this protein.
Showing 7 out of 8 products:
we uncover a novel polymorphism, rs187843643 (OR = 1.96; 95% CI = [1.54, 2.48]; P = 3.53 x 10-8), associated with melanoma. The SNP rs187842643 lies within a noncoding RNA 177kb downstream of BASP1 (brain associated protein-1). We find that BASP1 expression is suppressed in melanoma as compared with benign nevi, providing additional evidence for a putative role in melanoma pathogenesis.
Downregulation of BASP1 expression may play a role in the tumorigenesis of thyroid cancer.
Data suggest methylation status of gene promoters for BASP1 (brain abundant membrane attached signal protein 1) and CDH11 (cadherin 11) in tumor, skin, and metastatic tumor tissue may serve as prognostic biomarkers in patients with advanced melanoma.
Findings provide new insights into the function of prohibitin in transcriptional regulation and uncover a BASP1-prohibitin complex that plays an essential role in the PIP2-dependent recruitment of chromatin remodeling activities to the promoter.
Sequestration by BASP1 renders cells increasingly resistant to abrin toxicity.
Repression of transcription by WT1 (show WT1 Proteins)-BASP1 requires the myristoylation of BASP1 and the PIP2-dependent recruitment of histone deacetylase (show HDAC1 Proteins).
Results suggest that BASP1 and WT1 (show WT1 Proteins) play concerted, central roles in directing cell fate during differentiation. Here, BASP1/WT1 (show WT1 Proteins) work to divert K562 cells away from blood cell lineage toward neuron phenotype.
BASP1 and SRD5A2 (show SRD5A2 Proteins) are methylated in early hepatocellular carcinoma
BASP1 can confer WT1 (show WT1 Proteins) cosuppressor activity in transfection assays, and elimination of endogenous BASP1 expression augments transcriptional activation by WT1 (show WT1 Proteins).
proteomic assessments of membrane microdomains in prefrontal cortex and validation in two brain series, strongly implicates LAMP, STXBP1 (show STXBP1 Proteins) and BASP1 in schizophrenia and supports the view of a neuritic and synaptic dysfunction in the neuropathology
Ion channel activity of brain abundant protein BASP1 in planar lipid bilayer
BASP1 fragment truncated by the short N-terminal myristoylated peptide was unable to form oligomers.
This gene encodes a membrane bound protein with several transient phosphorylation sites and PEST motifs. Conservation of proteins with PEST sequences among different species supports their functional significance. PEST sequences typically occur in proteins with high turnover rates. Immunological characteristics of this protein are species specific. This protein also undergoes N-terminal myristoylation. Alternative splicing results in multiple transcript variants that encode the same protein.
brain abundant, membrane attached signal protein 1
, 22 kDa neuronal tissue-enriched acidic protein
, brain acid soluble protein 1
, brain acid-soluble protein 1
, neuronal axonal membrane protein NAP-22
, neuronal tissue-enriched acidic protein
, cytoskeleton associated protein 3
, brain acidic membrane protein
, 23 kDa cortical cytoskeleton-associated protein
, brain acid soluble protein 1 homolog
, particle bound cytosolic protein CAP23