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BEX2 belongs to the brain expressed X-linked gene family. Additionally we are shipping Brain Expressed X-Linked 2 Antibodies (6) and many more products for this protein.
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Bex2 (show BEX1 Proteins) affects the invasion and migration ability of glioma cells by regulating beta-catenin (show CTNNB1 Proteins)
Bex2 (show BEX1 Proteins) overexpression promoted cell migration and invasion in glioma cell lines.
Bex2 (show BEX1 Proteins) may be an important player during the development of glioma
Both BEX2 (show BEX1 Proteins) and INI1/hSNF5 (show SMARCB1 Proteins) mainly localized in cell nucleus.
BEX2 (show BEX1 Proteins) overexpression was associated with breast cancer.
BEX2 (show BEX1 Proteins) has a functional interplay with c-Jun (show JUN Proteins) and p65/RelA (show NFkBP65 Proteins) in breast cancer.
These results suggest that the conspicuous expression of the tumor suppressor genes BEX2 (show BEX1 Proteins), IGSF4 (show CADM1 Proteins) and TIMP3 (show TIMP3 Proteins) in MLLmu acute myeloid leukemias cell lines is the consequence of altered epigenetic properties of MLL (show MLL Proteins) fusion proteins.
hBex2 (show BEX1 Proteins) may act as a specific regulator during embryonic development by modulating the transcriptional activity of a novel E-box sequence-binding complex that contains hBex2 (show BEX1 Proteins), LMO2 (show LMO2 Proteins), NSCL2 (show NHLH2 Proteins) and LDB1 (show LDB1 Proteins).
Two novel brain expressed genes, BEX1 (show BEX1 Proteins) and BEX2 (show BEX1 Proteins) are identified; they are silenced in all glioma specimens and exhibit extensive promoter hypermethylation.
Correlation between BEX2 (show BEX1 Proteins) expression and mixed lineage leukemia chromosomal aberrations are shown in the cell lines.
enhanced STAT3 (show STAT3 Proteins)/NF-kappaB (show NFKB1 Proteins)-BEX2-VEGF (show VEGFA Proteins) signaling pathway contributes to hyperactive mTOR (show FRAP1 Proteins)-induced tumorigenesis
These results suggest the significance and potential applications of Bex2 in studies of endocrine and stem/progenitor cells.
Expression of ALDH1A2 (show ALDH1A1 Proteins), BEX2, EGR2 (show EGR2 Proteins), CCL3 (show CCL3 Proteins) and PLAU (show PLAU Proteins) are upregulated in Toxoplasma gondiisusceptible C57BL/6 mice.
We report the identification of an olfactory marker protein (show OMP Proteins) binding partner, Bex2, by phage-display screening of an olfactory mucosal cDNA-library
Bex1 and 2 have been characterized as interacting partners of the olfactory marker protein (OMP (show OMP Proteins)). Bex (show NGFRAP1 Proteins) immunoreactivity (ir) was primarily localized to neuronal cells within several regions of the brain.
This gene belongs to the brain expressed X-linked gene family. The encoded protein interacts with the transcription factor LIM domain only 2 in a DNA-binding complex that recognizes the E-box element and promotes transcription. This gene has been found to be a tumor suppressor that is silenced in human glioma. In breast cancer cells, this gene product modulates apoptosis in response to estrogen and tamoxifen, and enhances the anti-proliferative effect of tamoxifen. Multiple transcript variants encoding different isoforms have been found for this gene.
brain-expressed X-linked protein 2
, protein BEX2
, brain-expressed X-linked protein 2 homolog
, expression gene 2 in rat visual cortex