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Mediates the uptake of pyruvate into mitochondria.. Additionally we are shipping BRP44 Antibodies (47) and BRP44 Proteins (4) and many more products for this protein.
Our study indicates that MPC1 (show BRP44L ELISA Kits) and MPC2 expressions are of prognostic values in PCAs and that positive expression of MPC1 (show BRP44L ELISA Kits) or MPC2 is a predictor of favorable outcome.
a significant association between MPC2 variant rs10489202 and Schizophrenia susceptibility in Han Chinese (Meta-Analysis)
Results indicate mitochondrial pyruvate transporter (MPC) to be the key regulatory junction perturbed by virulent strains of Mycobacterium tuberculosis leading to alteration of mitochondrial metabolic flux and regulation of acetyl-CoA (show LPCAT2 ELISA Kits) formation.
These results reveal a novel post-translational regulation of MPC1 (show BRP44L ELISA Kits) by Sirt3 (show SIRT3 ELISA Kits), which is important for its activity and colon cancer cell growth.
Tumor cells expressing MPC1 (show BRP44L ELISA Kits) and MPC2 display increased mitochondrial pyruvate oxidation, with no changes in cell growth in adherent culture.
MPC2 acetylation is increased in Diabetic Heart mitochondria. This study supports the conclusion that deficient pyruvate transport activity, mediated in part by acetylation of MPC2, is a contributor to metabolic inflexibility in the diabetic heart.
Oxidative glutaminolysis supports the TCA cycle in mouse cells lacking MPC1 (show BRP44L ELISA Kits)/2.
Mediates the uptake of pyruvate into mitochondria.
brain protein 44
, protein 0-44