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Mediates the uptake of pyruvate into mitochondria.. Additionally we are shipping BRP44 Antibodies (48) and many more products for this protein.
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Our study indicates that MPC1 (show BRP44L Proteins) and MPC2 expressions are of prognostic values in PCAs and that positive expression of MPC1 (show BRP44L Proteins) or MPC2 is a predictor of favorable outcome.
a significant association between MPC2 variant rs10489202 and Schizophrenia susceptibility in Han Chinese (Meta-Analysis)
Results indicate mitochondrial pyruvate transporter (MPC) to be the key regulatory junction perturbed by virulent strains of Mycobacterium tuberculosis leading to alteration of mitochondrial metabolic flux and regulation of acetyl-CoA (show LPCAT2 Proteins) formation.
These results reveal a novel post-translational regulation of MPC1 (show BRP44L Proteins) by Sirt3 (show SIRT3 Proteins), which is important for its activity and colon cancer cell growth.
Tumor cells expressing MPC1 (show BRP44L Proteins) and MPC2 display increased mitochondrial pyruvate oxidation, with no changes in cell growth in adherent culture.
MPC2 (show CBX4 Proteins) acetylation is increased in Diabetic Heart mitochondria. This study supports the conclusion that deficient pyruvate transport activity, mediated in part by acetylation of MPC2 (show CBX4 Proteins), is a contributor to metabolic inflexibility in the diabetic heart.
Oxidative glutaminolysis supports the TCA cycle in mouse cells lacking MPC1 (show BRP44L Proteins)/2.
Mediates the uptake of pyruvate into mitochondria.
brain protein 44
, protein 0-44