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Brain and Acute Leukemia, Cytoplasmic Proteins (BAALC)

BAALC was identified by gene expression studies in patients with acute myeloid leukemia (AML). Additionally we are shipping BAALC Antibodies (40) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
BAALC 79870 Q8WXS3
BAALC 118452 Q8VHV1
BAALC 140720 Q920K5
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Top BAALC Proteins at antibodies-online.com

Showing 8 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$583.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,311.83
Details
Yeast Wild boar His tag   1 mg Log in to see 56 to 66 Days
$2,311.83
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$680.36
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   2 μg Log in to see 6 to 11 Days
$142.86
Details

BAALC Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

Rat (Rattus)

Top referenced BAALC Proteins

  1. Human BAALC Protein expressed in Escherichia coli (E. coli) - ABIN668049 : Tanner, Austin, Leone, Rush, Plass, Heinonen, Mrózek, Sill, Knuutila, Kolitz, Archer, Caligiuri, Bloomfield, de La Chapelle: BAALC, the human member of a novel mammalian neuroectoderm gene lineage, is implicated in hematopoiesis and acute leukemia. in Proceedings of the National Academy of Sciences of the United States of America 2001 (PubMed)
    Show all 2 references for ABIN668049

More Proteins for Brain and Acute Leukemia, Cytoplasmic (BAALC) Interaction Partners

Human Brain and Acute Leukemia, Cytoplasmic (BAALC) interaction partners

  1. BAALC and ERG (show ERG Proteins) genes are specific significant molecular markers in acute myeloid leukemia (show BCL11A Proteins) disease progression, response to treatment and survival.

  2. demonstrated that BAALC blocks ERK (show EPHB2 Proteins)-mediated monocytic differentiation of acute myeloid leukemia (show BCL11A Proteins) cells by trapping Kruppel-like factor 4 (KLF4 (show KLF4 Proteins)) in the cytoplasm and inhibiting its function in the nucleus

  3. combined determination of both miR (show MLXIP Proteins)-3151 and BAALC improved this prognostic stratification, with patients with low levels of both parameters showing a better outcome compared with those patients harboring increased levels of one or both markers

  4. study indicates that overexpression of BAALC serves as an independent prognostic biomarker in acute myeloid leukemia (show BCL11A Proteins)

  5. Evaluating WT1 (show WT1 Proteins) and BAALC gene expression at diagnosis may improve standard risk stratification and possibly refine the therapeutic approach for Myelodysplastic Syndromes patients.

  6. Thus low MDR1/low BAALC expression identifies a subgroup of intermediate cytogenetic risk AML (show RUNX1 Proteins) patients with a remarkably good long-term outcome achieved by chemotherapy alone.

  7. miR (show MLXIP Proteins)-3151 introns within BAALC have roles in driving leukemogenesis by deregulating the TP53 (show TP53 Proteins) pathway

  8. Higher BAALC expression and FLT3 (show FLT3 Proteins)-ITD mutation, both individually and in combination, were associated with worse survival outcomes in CN-AML (show RUNX1 Proteins), and this was also applicable in NPM1 (show NPM1 Proteins)-mutated CN-AML (show RUNX1 Proteins), known as a favorable-risk group.

  9. BAALC overexpression retains its negative prognostic role across all cytogenetic risk groups in acute myeloid leukemia (show BCL11A Proteins) patients.

  10. higher post-HSCT BAALC and WT1 (show WT1 Proteins) expressions in patients with CBF-AML (show RUNX1 Proteins) may be good markers of minimal residual disease for the prediction of survival and relapse after HSCT.

Mouse (Murine) Brain and Acute Leukemia, Cytoplasmic (BAALC) interaction partners

  1. BAALC/Baalc is a marker of the mesodermal lineage, especially muscle.

BAALC Protein Profile

Protein Summary

This gene was identified by gene expression studies in patients with acute myeloid leukemia (AML). The gene is conserved among mammals and is not found in lower organisms. Tissues that express this gene develop from the neuroectoderm. Multiple alternatively spliced transcript variants that encode different proteins have been described for this gene\; however, some of the transcript variants are found only in AML cell lines.

Gene names and symbols associated with BAALC

  • brain and acute leukemia, cytoplasmic (BAALC)
  • brain and acute leukemia, cytoplasmic (baalc)
  • brain and acute leukemia, cytoplasmic (Baalc)
  • 2810457D07Rik protein
  • BAALC protein
  • si:ch211-215i13.3 protein
  • si:zc215i13.3 protein

Protein level used designations for BAALC

brain and acute leukemia cytoplasmic protein , brain and acute leukemia, cytoplasmic

GENE ID SPECIES
612780 Canis lupus familiaris
614130 Bos taurus
368908 Danio rerio
420261 Gallus gallus
694238 Macaca mulatta
742690 Pan troglodytes
79870 Homo sapiens
118452 Mus musculus
100170128 Sus scrofa
140720 Rattus norvegicus
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