Branched Chain Amino-Acid Transaminase 1, Cytosolic (BCAT1) ELISA Kits

BCAT1 encodes the cytosolic form of the enzyme branched-chain amino acid transaminase. Additionally we are shipping BCAT1 Antibodies (94) and BCAT1 Proteins (12) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Rat BCAT1 BCAT1 29592 P54690
Anti-Human BCAT1 BCAT1 586 P54687
Anti-Mouse BCAT1 BCAT1 12035 P24288
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More ELISA Kits for BCAT1 Interaction Partners

Human Branched Chain Amino-Acid Transaminase 1, Cytosolic (BCAT1) interaction partners

  1. The tumor suppressive role of miR-218 was mediated by negatively regulating branched-chain amino acid transaminase 1 (BCAT1) protein expression. Importantly, overexpression of BCAT1 decreased the chemosensitivity to cis-diaminedichloroplatinum treatment of PC3 and DU145 cells.

  2. It has been demonstrated that branched-chain amino acid (BCAA (show ARID4B ELISA Kits)) catabolism is activated in human breast cancer, and abolishment of BCAA (show ARID4B ELISA Kits) catabolism by knocking down BCAT1 inhibits breast cancer cell growth by repressing mTOR (show FRAP1 ELISA Kits)-mediated mitochondrial biogenesis and function.

  3. BCAT1 expression is significantly upregulated in human masticatory mucosa during wound healing

  4. Mechanistic investigation revealed that BCAT1 might be an important regulator responsible for DOT1L (show DOT1L ELISA Kits)-mediated sphere formation and cell migration in breast cancer cells

  5. BCAT1 overexpression is associated with advanced tumour status, and implies adverse clinical outcomes of urothelial carcinoma

  6. BCAT1 is strongly overexpressed in ovarian cancer.

  7. Focal deletions of the BCAT1 were associated with B-cell precursor acute lymphoblastic leukemia.

  8. levels of branched-chain aminotransferase-1 (BCAT1) transcripts are significantly decreased on the polysomes of both RPS19 (show RPS19 ELISA Kits) and RPL11 (show RPL11 ELISA Kits) cells and that translation of BCAT1 protein is especially impaired in cells with small RP gene mutations

  9. Over-expression of BCAT1, a c-Myc (show MYC ELISA Kits) target gene, induces cell proliferation, migration and invasion in nasopharyngeal carcinoma.

  10. A central role for BCAT1 in glioma pathogenesis, making BCAT1 and branched-chain amino acids metabolism attractive targets for the development of targeted therapeutic approaches to treat patients with glioblastoma.

Mouse (Murine) Branched Chain Amino-Acid Transaminase 1, Cytosolic (BCAT1) interaction partners

  1. results suggest transcriptional adaptations occur in BCATm (show BCAT2 ELISA Kits) KO mice that along with altered nutrient signaling may contribute to their previously reported protein turnover, metabolic and exercise phenotypes

  2. BCATc as a novel regulator of T cell activation and metabolism

  3. leucine supplementation increased the expression of enzymes (BCAT1, BCAT2 (show BCAT2 ELISA Kits) and BCKDK (show BCKDK ELISA Kits)) that metabolize branched-chain amino acids.

  4. analysis of the biochemical mechanism of BCATm (show BCAT2 ELISA Kits) (branched-chain aminotransferase) catalysis of reversible transamination of leucine and alpha-ketoglutarate to KIC and glutamate (show GRIN1 ELISA Kits)

  5. Bcat1 is a candidate for the type I diabetes susceptibility locus Idd6

  6. Bcat1 is part of the complex multigenic Pas1 locus, with a functional role for its intragenic polymorphisms in lung tumor susceptibility.

  7. These results demonstrate that the expression of the BCATc gene in the brain is specifically regulated by BDNF (show BDNF ELISA Kits) in a time- and region-dependent fashion.

  8. BCATc mRNA gradually appears in different brain regions starting from early stages of neural development, and is maintained until adulthood.

  9. BCATm (show BCAT2 ELISA Kits)(-/-) mice had elevated plasma branched-chain amino acids & decreased adiposity & body weight, despite eating more food, along with increased energy expenditure, improvements in glucose & insulin (show INS ELISA Kits) tolerance & protection from diet-induced obesity

BCAT1 Antigen Profile

Antigen Summary

This gene encodes the cytosolic form of the enzyme branched-chain amino acid transaminase. This enzyme catalyzes the reversible transamination of branched-chain alpha-keto acids to branched-chain L-amino acids essential for cell growth. Two different clinical disorders have been attributed to a defect of branched-chain amino acid transamination: hypervalinemia and hyperleucine-isoleucinemia. As there is also a gene encoding a mitochondrial form of this enzyme, mutations in either gene may contribute to these disorders. Alternatively spliced transcript variants have been described.

Gene names and symbols associated with BCAT1

  • branched chain aminotransferase 1, cytosolic (bcat1) antibody
  • branched chain amino-acid transaminase 1, cytosolic (BCAT1) antibody
  • branched chain amino-acid transaminase 1, cytosolic (bcat1) antibody
  • branched chain amino acid transaminase 1, cytosolic (Bcat1) antibody
  • branched chain aminotransferase 1, cytosolic (Bcat1) antibody
  • BCATc antibody
  • BCT1 antibody
  • Eca39 antibody
  • fj66g02 antibody
  • MECA39 antibody
  • PNAS121 antibody
  • PP18 antibody
  • wu:fj66g02 antibody
  • zgc:73157 antibody

Protein level used designations for BCAT1

branched-chain-amino-acid aminotransferase, cytosolic , branched chain aminotransferase 1, cytosolic , branched chain amino-acid transaminase 1, cytosolic , branched-chain-amino-acid aminotransferase, cytosolic-like , BCAT(c) , placental protein 18 , cytosolic branched-chain amino acid aminotransferase

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100591100 Nomascus leucogenys
29592 Rattus norvegicus
586 Homo sapiens
418193 Gallus gallus
486633 Canis lupus familiaris
505926 Bos taurus
443485 Ovis aries
12035 Mus musculus
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