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Breakpoint Cluster Region (BCR) ELISA Kits

A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. Additionally we are shipping BCR Antibodies (148) and BCR Proteins (5) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
BCR 613 P11274
BCR 110279 Q6PAJ1
Anti-Rat BCR BCR 309696  
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Top BCR ELISA Kits at antibodies-online.com

Showing 6 out of 12 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Guinea Pig
96 Tests Log in to see 11 to 13 Days
$801.43
Details
Human
96 Tests Log in to see 2 to 3 Days
$450.00
Details
All Species 24.7ng/mL 61.73-5000 ng/mL 96 Tests Log in to see 11 to 12 Days
$850.17
Details
Human
96 Tests Log in to see 11 to 13 Days
$875.60
Details
Mouse
96 Tests Log in to see 11 to 13 Days
$875.60
Details
Chicken
96 Tests Log in to see 16 to 21 Days
$999.43
Details

More ELISA Kits for BCR Interaction Partners

Human Breakpoint Cluster Region (BCR) interaction partners

  1. Identify a novel BCR-ABL (show ABL1 ELISA Kits)/IkappaBalpha (show NFKBIA ELISA Kits)/p53 (show TP53 ELISA Kits) network, whereby BCR-ABL (show ABL1 ELISA Kits) functionally inactivates a key tumor suppressor in chronic myeloid leukemia (show BCL11A ELISA Kits).

  2. Blockade of the interaction between Bcr-Abl and PTB1B by small molecule SBF-1 to overcomes imatinib-resistance of K562 cells.

  3. BCR-ABL1 transcript types found in Syria were similar to that of Indian Far-Eastern, African or European populations. The M-BCR rearrangement types were not dependent on white blood count, platelet count, hemoglobin level or gender of the patients.

  4. Data suggest elevated interleukin-1beta secretion from tyrosine kinase (show TXK ELISA Kits) inhibitor- (TKI-)resistant chronic myeloid leukemia (show BCL11A ELISA Kits) (CML) cells contributes to TKI/imatinib resistance via promotion of cell viability/migration; cells used lack BCR-ABL (show ABL1 ELISA Kits) mutation.

  5. Higher incidence of BCR-ABL and lower incidence of TEL-AML1 are associated with acute lymphoblastic leukemia.

  6. Suggest that AIC-47 in combination with imatinib strengthened the attack on cancer energy metabolism in BCR-ABL (show ABL1 ELISA Kits)-harboring leukemic cells.

  7. Molecular rearrangements and the minimal residual disease follow-up for 5 chronic myeloid leukaemia patients; 3 resulted from new rearrangements between the BCR and ABL1 (show ABL1 ELISA Kits) sequences (the breakpoints being located within BCR exon 13 in 2 cases and within BCR exon 18 in one case). The other 2 cases revealed a complex e8-[ins (show INS ELISA Kits)]-a2 fusion transcript involving a 3rd partner gene.

  8. analysis of WT1 and M-BCR-ABL expressions in chronic myeloid leukemia reveals that high WT1 expression in CML patients is detected especially in the advanced stages of the disease

  9. BCR-ABL kinase domain mutation is associated with Philadelphia-positive leukemia.

  10. Separase (show ESPL1 ELISA Kits) protein levels decrease and Separase (show ESPL1 ELISA Kits) proteolytic activity increases exclusively in b3a2 p210BCR-ABL (show ABL1 ELISA Kits)-positive cell lines under Imatinib treatment.

Mouse (Murine) Breakpoint Cluster Region (BCR) interaction partners

  1. The resistance in BCR-ABL1 (show ABL1 ELISA Kits) cells resulted either from the Y253H mutation in the BCR-ABL1 (show ABL1 ELISA Kits) gene or incubation in increasing concentrations of imatinib.

  2. PDZK1 (show PDZK1 ELISA Kits) has novel SR-BI (show SCARB1 ELISA Kits)-independent function in VSM that affords protection from neointima formation, and this involves PDZK1 (show PDZK1 ELISA Kits) suppression of VSM cell proliferation via an inhibitory interaction with Bcr

  3. Hap1 (show HAP1 ELISA Kits) interacts with Bcr on microtubules to regulate neuronal differentiation.

  4. Grb10 (show GRB10 ELISA Kits) is involved in BCR-ABL (show ABL1 ELISA Kits)-positive leukemia in mice.

  5. Bcr is an integral member of the Par (show AFG3L2 ELISA Kits)-Tiam1 complex that controls polarized cell migration by locally restricting both Rac1 and PKCzeta (show PRKCZ ELISA Kits) function.

  6. Loss of Bcr expression causes defects in spine development.

  7. Suggest that HS-438 may be a novel drug candidate with the therapeutic potential to target BCR-ABL (show ABL1 ELISA Kits) and overcome imatinib resistance in patients with chronic myeloid leukemia (show BCL11A ELISA Kits).

  8. IRF8 (show IRF8 ELISA Kits)-rescued BCR-ABL (show ABL1 ELISA Kits)-expressing dendritic cells were capable of inducing CTLs more efficiently than control dendritic cells.

  9. study provided evidence for a novel, BCR-ABL (show ABL1 ELISA Kits)-mediated antiapoptotic mechanism, which results from the increased acetylation of p53 (show TP53 ELISA Kits) at the K317/K320 residue, thus preventing the nuclear export of p53 (show TP53 ELISA Kits) in response to DNA damage.

  10. Intrafemoral transplantation of BCR-ABL-transduced Cbl-b(-/-) cells revealed equivalent latency of disease development to the wild-type transplants

BCR Antigen Profile

Antigen Summary

A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with BCR

  • breakpoint cluster region (bcr) antibody
  • breakpoint cluster region (BCR) antibody
  • breakpoint cluster region (Bcr) antibody
  • 5133400C09Rik antibody
  • AI561783 antibody
  • AI853148 antibody
  • ALL antibody
  • BCR antibody
  • BCR1 antibody
  • CML antibody
  • D22S11 antibody
  • D22S662 antibody
  • mKIAA3017 antibody
  • PHL antibody
  • si:dkey-83d9.7 antibody
  • zK83D9.7 antibody

Protein level used designations for BCR

breakpoint cluster region , breakpoint cluster region protein-like , BCR/FGFR1 chimera protein , FGFR1/BCR chimera protein , breakpoint cluster region protein , renal carcinoma antigen NY-REN-26 , breakpoint cluster region homolog

GENE ID SPECIES
568320 Danio rerio
100393591 Callithrix jacchus
100431481 Pongo abelii
458694 Pan troglodytes
100554393 Anolis carolinensis
613 Homo sapiens
110279 Mus musculus
309696 Rattus norvegicus
100157974 Sus scrofa
100718992 Cavia porcellus
416952 Gallus gallus
607482 Canis lupus familiaris
789892 Bos taurus
Selected quality suppliers for BCR (BCR) ELISA Kits
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