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Breast Cancer Metastasis Suppressor 1 Proteins (BRMS1)

BRMS1 reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. Additionally we are shipping BRMS1 Antibodies (61) and BRMS1 Kits (5) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
BRMS1 25855 Q9HCU9
BRMS1 107392 Q99N20
BRMS1 293668 Q5M7T3
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Top BRMS1 Proteins at antibodies-online.com

Showing 9 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human GST tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,629.00
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,629.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   20 μg Log in to see 3 to 4 Days
$388.93
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 16 to 21 Days
$314.29
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

BRMS1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Rat (Rattus)

More Proteins for Breast Cancer Metastasis Suppressor 1 (BRMS1) Interaction Partners

Human Breast Cancer Metastasis Suppressor 1 (BRMS1) interaction partners

  1. Phosphorylation of BRMS1 by CDK2 (show CDK2 Proteins) regulates the migration of tumor cells.

  2. Data show that Cullin3 exerts its function through promoting breast-cancer metastasis suppressor 1 (BRMS1) protein degradation, which was associated with epithelial-mesenchymal transition (EMT (show ITK Proteins)), migration and invasion.

  3. The studies reviewed here with respect to BRMS1 structure, cellular effects, intracellular signaling, and clinical value consolidate the importance of BRMS1 in the development of metastasis.

  4. Aberrant methylation of BRMS1 frequently occurs in the down-regulation of BRMS1 in triple negative breast cancer and that it may play a role in the metastasis of breast cancer.

  5. the present study demonstrates a mechanical cascade of BRMS1 suppressing cancer cell invasion through downregulating HIF-1alpha (show HIF1A Proteins) transcript and consequently reducing Snail (show SNAI1 Proteins) and TWIST1 (show TWIST1 Proteins) expression.

  6. MRTF-A and STAT3 (show STAT3 Proteins) synergistically recruited DNMT1 (show DNMT1 Proteins) to hypermethylate the promoter of BRMS1 and affect the expression of BRMS1.MRTF-A and STAT3 (show STAT3 Proteins) promote breast cancer cell migration via hypermethylating BRSM1.

  7. BRMS1 expression in human breast cancer is negatively correlated with JARID1C (show KDM5C Proteins) expression. Our results, for the first time, portray a pivotal role of JARID1C (show KDM5C Proteins) in regulating metastatic behaviors of breast cancer cells

  8. loss of BRMS1 promotes malignant phenotypes that are dependent on NF-kappaB (show NFKB1 Proteins)-dependent regulation of Twist1 (show TWIST1 Proteins)

  9. BRMS1 is a key regulator required to maintain a cellular morphology and cytoskeletal architecture consistent with an epithelial phenotype.

  10. BRMS1 overexpression inhibited glioma cell invasion.

Mouse (Murine) Breast Cancer Metastasis Suppressor 1 (BRMS1) interaction partners

  1. findings indicate the expression of Brms1L (show BRMS1L Proteins) depends on beta-catenin (show CTNNB1 Proteins) activity and contributes to follicle stimulating hormone beta (show FSHB Proteins) induction by Gonadotropin-Releasing Hormone.

  2. The Brms1 suppressed pulmonary metastasis and promoted apoptosis of tumor cells located in the lungs but not in the mammary glands.

  3. BRMS1 may participate in transcriptional regulation via interaction with the mSin3.HDAC (show HDAC3 Proteins) complex

  4. results show for the first time that BRMS1 contains both nuclear import and export signals enabling its nucleo-cytoplasmic shuttling

BRMS1 Protein Profile

Protein Summary

This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms.

Gene names and symbols associated with BRMS1

  • breast cancer metastasis suppressor 1 (brms1)
  • breast cancer metastasis suppressor 1 (BRMS1)
  • breast cancer metastasis-suppressor 1 (Brms1)
  • breast cancer metastasis-suppressor 1-like (Brms1l)
  • breast cancer metastasis-suppressor 1-like (BRMS1L)
  • 0710008O11Rik protein
  • AI159718 protein
  • AV003220 protein
  • AW554636 protein
  • BRMS1 protein
  • BRMS1L protein
  • D12Ertd407e protein
  • MGC98869 protein

Protein level used designations for BRMS1

breast cancer metastasis suppressor 1 , breast cancer metastasis-suppressor 1 , breast cancer metastasis-suppressor 1 homolog , breast cancer metastasis-suppressor 1-like protein

GENE ID SPECIES
734272 Xenopus laevis
25855 Homo sapiens
615952 Bos taurus
611920 Canis lupus familiaris
107392 Mus musculus
293668 Rattus norvegicus
52592 Mus musculus
100307034 Ovis aries
Selected quality suppliers for BRMS1 Proteins (BRMS1)
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