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anti-Brevican (BCAN) Antibodies

BCAN encodes a member of the lectican family of chondroitin sulfate proteoglycans that is specifically expressed in the central nervous system. Additionally we are shipping Brevican Kits (34) and Brevican Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
BCAN 12032 Q61361
BCAN 25393 P55068
BCAN 63827 Q96GW7
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Top anti-Brevican Antibodies at antibodies-online.com

Showing 10 out of 79 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Dog Mouse Un-conjugated IF, WB Western blot analysis of Brevican on a rat cerebrum lysate. Lane 1: 1:1000, lane 2: 1:2000, lane 3: 1:4000 dilution of the mouse anti-Brevican antibody. 50 μg Log in to see 5 to 6 Days
$205.42
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-BCAN Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Hela cell lysate WB Suggested Anti-BCAN  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500  Positive Control: Hela cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB BCAN Antibody (C-term) (ABIN652096) western blot analysis in CEM cell line lysates (35 µg/lane). This demonstrates the BCAN antibody detected the BCAN protein (arrow). BCAN antibody (C-term) (ABIN652096) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Mouse Mouse HRP ICC, IF, WB   100 μg Log in to see 3 to 4 Days
$422.40
Details
Mouse Mouse FITC ICC, IF, WB   100 μg Log in to see 3 to 4 Days
$426.80
Details
Mouse Mouse Alkaline Phosphatase (AP) ICC, IF, WB   100 μg Log in to see 3 to 4 Days
$429.00
Details
Mouse Mouse Biotin ICC, IF, WB   100 μg Log in to see 3 to 4 Days
$431.20
Details
Mouse Mouse PE ICC, IF, WB   100 μg Log in to see 3 to 4 Days
$432.30
Details
Mouse Mouse Streptavidin ICC, IF, WB   100 μg Log in to see 3 to 4 Days
$433.40
Details
Mouse Mouse APC ICC, IF, WB   100 μg Log in to see 3 to 4 Days
$434.50
Details

BCAN Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine)
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Rat (Rattus)
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Top referenced anti-Brevican Antibodies

  1. Dog (Canine) Monoclonal BCAN Primary Antibody for IF, WB - ABIN968235 : Aspberg, Miura, Bourdoulous, Shimonaka, Heinegârd, Schachner, Ruoslahti, Yamaguchi: The C-type lectin domains of lecticans, a family of aggregating chondroitin sulfate proteoglycans, bind tenascin-R by protein-protein interactions independent of carbohydrate moiety. in Proceedings of the National Academy of Sciences of the United States of America 1997 (PubMed)
    Show all 3 references for ABIN968235

  2. Mouse (Murine) Monoclonal BCAN Primary Antibody for ICC, IF - ABIN2483323 : Rauch, Meyer, Brakebusch, Seidenbecher, Gundelfinger, Beier, Fässler: Sequence and chromosomal localization of the mouse brevican gene. in Genomics 1997 (PubMed)

More Antibodies against Brevican Interaction Partners

Mouse (Murine) Brevican (BCAN) interaction partners

  1. The extracellular matrix molecule brevican is an integral component of the machinery mediating fast synaptic transmission at the calyx of Held

  2. This study provided evidence that the brevican modulates synaptogenesis and long-term synapse stability. The mutant neurons display reduced frequencies of mEPSCs and mIPSCs.

  3. these results imply that Bral2 (show HAPLN4 Antibodies)-brevican interaction may play a key role in synaptic stabilization and the structural integrity of brain perineuronal nets

  4. defective brevican processing observed in amyloid beta-bearing mice may contribute to deficient neural plasticity

  5. Results indicate that reactive gliosis differs between the spinal cord dorsal root entry zone and dorsal column and that Brevican and Versican (show Vcan Antibodies) may participate in the inhibitory properties of the dorsal root entry zone.

  6. Brevican is not essential for learning and memory, but plays a role in long-term potentiation in mice

  7. Brevican and the ADAMTS (show ADAMTS1 Antibodies)-cleaved fragment of brevican were most broadly distributed in neuropil in the brain.

  8. The proteoglycan (show Vcan Antibodies) brevican binds to fibronectin (show FN1 Antibodies) after proteolytic cleavage and promotes glioma cell motility

  9. This study show that brevican plays a crucial role in determining the specialization of the hyaluronan-binding nodal matrix assemblies in large diameter nodes.

Human Brevican (BCAN) interaction partners

  1. Data indicate that median methylation levels of BCAN, HOXD1 (show HOXD1 Antibodies), KCTD8 (show KCTD8 Antibodies), KLF11 (show KLF11 Antibodies), NXPH1 (show NXPH1 Antibodies), POU4F1 (show POU4F1 Antibodies), SIM1 (show SIM1 Antibodies), and TCF7L1 (show TCF3 Antibodies) were >/=30% higher than in normal samples, representing potential biomarkers for tumor diagnosis.

  2. High Brevican is associated with the invasive phenotype of low-grade astrocytoma.

  3. Authors describe the expression of BEHAB/brevican in human brain and characterize two novel glioma-specific isoforms which are generated by differential glycosylation and are absent from normal adult brain and other neuropathologies.

  4. These results demonstrate for the first time that ADAMTS-5 (show ADAMTS5 Antibodies) is capable of degrading brevican and is overexpressed in glioblastoma cells, and suggest that ADAMTS-5 (show ADAMTS5 Antibodies) may play a role in glioma cell invasion through the cleavage of brevican.

  5. The proteoglycan (show Vcan Antibodies) brevican binds to fibronectin (show FN1 Antibodies) after proteolytic cleavage and promotes glioma cell motility

Brevican (BCAN) Antigen Profile

Protein Summary

This gene encodes a member of the lectican family of chondroitin sulfate proteoglycans that is specifically expressed in the central nervous system. This protein is developmentally regulated and may function in the formation of the brain extracellular matrix. This protein is highly expressed in gliomas and may promote the growth and cell motility of brain tumor cells. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with anti-Brevican (BCAN) Antibodies

  • brevican (bcan) antibody
  • brevican (BCAN) antibody
  • brain enriched hyaluronan binding protein (BEHAB) antibody
  • brevican (Bcan) antibody
  • ALPBRE antibody
  • BCAN antibody
  • BEHAB antibody
  • CSPG7 antibody
  • fi32a12 antibody
  • wu:fi32a12 antibody
  • Xbcan antibody

Protein level used designations for anti-Brevican (BCAN) Antibodies

brevican core protein , brevican , brevican core protein-like , brevican soluble core protein , Brevican core protein , brain-enriched hyaluronan-binding protein , BEHAB , brevican (brain specific proteoglycan in the aggrecan family) , chondroitin sulfate proteoglycan 7 , chondroitin sulfate proteoglycan BEHAB , chondroitin sulfate proteoglycan BEHAB/brevican

GENE ID SPECIES
334113 Danio rerio
457401 Pan troglodytes
100064356 Equus caballus
100456431 Pongo abelii
398229 Xenopus laevis
100582450 Nomascus leucogenys
727695 Felis catus
12032 Mus musculus
25393 Rattus norvegicus
63827 Homo sapiens
281019 Bos taurus
100339573 Oryctolagus cuniculus
100714598 Cavia porcellus
612102 Canis lupus familiaris
425976 Gallus gallus
101105963 Ovis aries
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