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Bromodomain and WD Repeat Domain Containing 1 Proteins (BRWD1)

BRWD1 encodes a member of the WD repeat protein family. Additionally we are shipping BRWD1 Antibodies (29) and BRWD1 Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
BRWD1 54014 Q9NSI6
Mouse BRWD1 BRWD1 93871 Q921C3
Rat BRWD1 BRWD1 304061  
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Top BRWD1 Proteins at antibodies-online.com

Showing 2 out of 2 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human His tag,DYKDDDDK Tag Recombinant BRWD1 (1310-1430) protein gel. BRWD1 (1310-1430) protein was run on an SDS-PAGE gel and stained with Coomassie blue. 100 μg Log in to see 1 to 2 Days
$460.83
Details

BRWD1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,

More Proteins for Bromodomain and WD Repeat Domain Containing 1 (BRWD1) Interaction Partners

Human Bromodomain and WD Repeat Domain Containing 1 (BRWD1) interaction partners

  1. RNA-seq evidence of biallelic expression of BRWD1 and 10 neighboring genes in at least one primary human tissue tested indicates that the expression of BRWD1 is uncoupled from the control of the maternally inherited 5mCpG imprints at the WRB (show WRB Proteins) differentially methylated region (DMR (show WDR20 Proteins)) in disomic controls or trisomy (Down syndrome) individuals.

Mouse (Murine) Bromodomain and WD Repeat Domain Containing 1 (BRWD1) interaction partners

  1. BRWD1 is essential in females for epigenetic control of meiotic chromosome stability and in males for haploid gene transcription during postmeiotic sperm differentiation.

  2. WDR9 is a transcriptional regulator involved in chromatin remodeling through the action of two bromodomains and contacts to the SWI (show SMARCA1 Proteins)/SNF (show SNRPA Proteins) complex

  3. Brwd1 represents one of a small number of genes whose elimination disrupts gametogenesis in both sexes after the major events of meiotic prophase I have been completed.

BRWD1 Protein Profile

Protein Summary

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD) residues which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 2 bromodomains and multiple WD repeats. This gene is located within the Down syndrome region-2 on chromosome 21. Alternative splicing of this gene generates multiple transcript variants encoding distinct isoforms. In mouse, this gene encodes a nuclear protein that has a polyglutamine-containing region that functions as a transcriptional activation domain which may regulate chromatin remodelling and associates with a component of the SWI/SNF chromatin remodelling complex.

Gene names and symbols associated with BRWD1

  • bromodomain and WD repeat domain containing 1 (BRWD1)
  • bromodomain and WD repeat domain containing 1 (LOC100226455)
  • bromodomain and WD repeat domain containing 1 (brwd1)
  • bromodomain and WD repeat domain containing 1 (Brwd1)
  • 5330419I02Rik protein
  • BRWD1 protein
  • C21orf107 protein
  • D530019K20Rik protein
  • G1-403-16 protein
  • N143 protein
  • repro5 protein
  • Wdr9 protein

Protein level used designations for BRWD1

bromodomain and WD repeat domain containing 1 , WD repeat domain 9 , bromodomain and WD repeat domain containing 1, isoform 1 , bromodomain and WD repeat-containing protein 1-like , WD repeat protein WDR9-form2 , WD repeat-containing protein 9 , bromodomain and WD repeat-containing protein 1 , transcriptional unit N143

GENE ID SPECIES
418521 Gallus gallus
473998 Pan troglodytes
487764 Canis lupus familiaris
715714 Macaca mulatta
100079801 Ornithorhynchus anatinus
100137594 Papio anubis
100226455 Taeniopygia guttata
100328651 Oryctolagus cuniculus
100494345 Xenopus (Silurana) tropicalis
100547202 Meleagris gallopavo
100554675 Anolis carolinensis
100603404 Nomascus leucogenys
54014 Homo sapiens
540661 Bos taurus
93871 Mus musculus
304061 Rattus norvegicus
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