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anti-Budding Uninhibited By Benzimidazoles 1 Homolog (Yeast) (BUB1) Antibodies

BUB1 encodes a kinase involved in spindle checkpoint function. Additionally we are shipping BUB1 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
BUB1 699 O43683
BUB1 296137  
BUB1 12235 O08901
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Top anti-BUB1 Antibodies at antibodies-online.com

Showing 10 out of 142 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated FACS, WB BUB1A Antibody (N-term) (ABIN651630) western blot analysis in A549 cell line lysates (35 µg/lane). This demonstrates the BUB1A antibody detected the BUB1A protein (arrow). BUB1A Antibody (N-term) (ABIN651630) flow cytometric analysis of A549 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma BUB1A Antibody (F1058) (ABIN392626) western blot analysis in T47D cell line lysates (35 µg/lane).This demonstrates the BUB1A antibody detected the BUB1A protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using BUB1 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Mouse Mouse Un-conjugated ICC, FACS, IF, IHC (p), WB 50 μL Log in to see 5 to 6 Days
$402.29
Details
Human Rabbit Un-conjugated EIA, IF, WB Immunocytochemistry of Bub1 in A20 cells with AP30171PU-N Bub1 antibody at 10 μg/ml. Western blot analysis of bub1 in A-20 lysate with AP30171PU-N bub1 antibody at (A) 2 and (B) 4 μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Mouse Un-conjugated IF, IP, WB   50 μg Log in to see 6 to 8 Days
$566.50
Details
Human Rabbit Un-conjugated IHC (p), WB 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Mouse Un-conjugated ICC, IF   100 μg Log in to see 1 to 2 Days
$466.67
Details

BUB1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-BUB1 Antibodies

  1. Human Polyclonal BUB1 Primary Antibody for EIA, IHC (p) - ABIN360514 : Shichiri, Yoshinaga, Hisatomi, Sugihara, Hirata: Genetic and epigenetic inactivation of mitotic checkpoint genes hBUB1 and hBUBR1 and their relationship to survival. in Cancer research 2002 (PubMed)
    Show all 5 references for ABIN360514

  2. Mouse (Murine) Monoclonal BUB1 Primary Antibody for ICC, FACS - ABIN108553 : Liu, Hittle, Jablonski, Campbell, Yoda, Yen: Human CENP-I specifies localization of CENP-F, MAD1 and MAD2 to kinetochores and is essential for mitosis. in Nature cell biology 2003 (PubMed)
    Show all 4 references for ABIN108553

  3. Human Monoclonal BUB1 Primary Antibody for IF, IP - ABIN181741 : Vanoosthuyse, Hardwick: Bub1 and the multilayered inhibition of Cdc20-APC/C in mitosis. in Trends in cell biology 2005 (PubMed)
    Show all 3 references for ABIN181741

  4. Human Polyclonal BUB1 Primary Antibody for IHC (p), WB - ABIN392626 : Cayrol, Cougoule, Wright: The beta2-adaptin clathrin adaptor interacts with the mitotic checkpoint kinase BubR1. in Biochemical and biophysical research communications 2002 (PubMed)
    Show all 2 references for ABIN392626

  5. Human Polyclonal BUB1 Primary Antibody for FACS, WB - ABIN651630 : Gambe, Matsunaga, Takata, Ono-Maniwa, Baba, Uchiyama, Fukui: A nucleolar protein RRS1 contributes to chromosome congression. in FEBS letters 2009 (PubMed)
    Show all 2 references for ABIN651630

  6. Human Monoclonal BUB1 Primary Antibody for ICC, IF - ABIN2668285 : Liu, Rattner, Jablonski, Yen: Mapping the assembly pathways that specify formation of the trilaminar kinetochore plates in human cells. in The Journal of cell biology 2006 (PubMed)

  7. Human Polyclonal BUB1 Primary Antibody for ELISA, WB - ABIN1452063 : Cahill, da Costa, Carson-Walter, Kinzler, Vogelstein, Lengauer: Characterization of MAD2B and other mitotic spindle checkpoint genes. in Genomics 1999 (PubMed)

  8. Human Polyclonal BUB1 Primary Antibody for EIA, IF - ABIN499509 : Pangilinan, Li, Weaver, Lewis, Dang, Spencer: Mammalian BUB1 protein kinases: map positions and in vivo expression. in Genomics 1998 (PubMed)

  9. Human Polyclonal BUB1 Primary Antibody for IHC, ELISA - ABIN1533511 : Cahill, Lengauer, Yu, Riggins, Willson, Markowitz, Kinzler, Vogelstein: Mutations of mitotic checkpoint genes in human cancers. in Nature 1998 (PubMed)

More Antibodies against BUB1 Interaction Partners

Human Budding Uninhibited By Benzimidazoles 1 Homolog (Yeast) (BUB1) interaction partners

  1. Bub1 may be associated with cancer stem cell potential.

  2. Both Bub1 and BubR1 (show BUB1B Antibodies) bind stably to Bub3 (show BUB3 Antibodies) that is required for kinetochore localization of the proteins

  3. Bub1-Plk1 (show PLK1 Antibodies)-mediated phosphorylation of Cdc20 (show CDC20 Antibodies) constitutes an anaphase-promoting complex or cyclosome-inhibitory mechanism that is parallel, but not redundant, to mitotic checkpoint (show BUB3 Antibodies) complex formation.

  4. Data show that mitotic checkpoint (show BUB3 Antibodies) kinase (show ATR Antibodies) Bub1 is an active kinase regulated by intra-molecular phosphorylation at the P+1 loop.

  5. human BUB1 does not associate stably with the MAD2 (show MAD2L1 Antibodies) activator MAD1 (show MXD1 Antibodies) (also known as MAD1L1 (show MAD1L1 Antibodies)) and, although required for accelerating the loading of MAD1 (show MXD1 Antibodies) onto kinetochores, BUB1 is dispensable for the maintenance of steady-state levels of MAD1 (show MXD1 Antibodies) there

  6. MAD2L1 (show MAD2L1 Antibodies) and BUB1 may play important roles in breast cancer progression, and measuring the expression of these genes may assist the prediction of breast cancer prognosis.

  7. Data provide novel insight into the regulation and kinetochore residency of Bub1 and indicate that its localization is dynamic and tightly controlled through feedback autophosphorylation.

  8. Bub1 coordinates checkpoint signalling by distinct domains for RZZ and BubR1 (show BUB1B Antibodies) recruitment and localizes antagonistic checkpoint activities.

  9. BUB1B (show BUB1B Antibodies) expression was highly correlated to CDC20 (show CDC20 Antibodies) and CCNB1 (show CCNB1 Antibodies) expression in multiple myeloma cells, leading to increased cell proliferation.Bub1 expression promotes cell proliferation and leads to poor survival in multiple myeloma patients

  10. BubR1 (show BUB1B Antibodies) is a component of the Mitotic checkpoint (show BUB3 Antibodies) complex and was reported to be overexpressed in Breast cancer. BubR1 (show BUB1B Antibodies) overexpression was correlated with poor survival in early stage Breast cancer patients.

Mouse (Murine) Budding Uninhibited By Benzimidazoles 1 Homolog (Yeast) (BUB1) interaction partners

  1. Bub1 coordinates checkpoint signalling by distinct domains for RZZ and BubR1 (show BUB1B Antibodies) recruitment and localizes antagonistic checkpoint activities.

  2. It was shown that that Bub1 kinase activity integrates attachment error correction and mitotic checkpoint signaling by controlling the localization and activity of Aurora B kinase through phosphorylation of histone H2A at threonine 121.

  3. Results establish that Bub1 has oncogenic properties and suggest that Aurora B (show AURKC Antibodies) is a critical target through which overexpressed Bub1 drives aneuploidization and tumorigenesis.

  4. It seems that Sgo1 (show SGOL1 Antibodies) sets up the centromeric protection mechanism in G2, but that its Bub1-dependent localisation to centromeres during mitosis is not required to maintain cohesion.

  5. mutations of Bub1 and BubR1 (show BUB1B Antibodies) found in Brca2 (show BRCA2 Antibodies)- mutant mice indeed are responsible for the chromosome instability in Brca2 (show BRCA2 Antibodies)-mutated tumors

  6. Our data suggest that Bub1 is a critical spindle checkpoint protein that regulates accurate chromosome alignment and homolog disjunction in mammalian oocyte meiosis.

  7. Bub1 is important for mediating cell death when chromosomes missegregate.

  8. Bub1 is essential for proper chromosome segregation, a defect that can lead to severe phenotypes, including perinatal lethality and a predisposition to cancer.

  9. Data show that the anaphase-promoting complex is activated in an exponential fashion after germinal vesicle breakdown in oocytes and that this process is advanced by 5 hr in oocytes lacking Bub1.

  10. Bub1 dysfunction is linked to inherited aneuploidy in female germ cells and may contribute to the maternal age-related increase in aneuploidy and pregnancy loss.

BUB1 Antigen Profile

Protein Summary

This gene encodes a kinase involved in spindle checkpoint function. The kinase functions in part by phosphorylating a member of the miotic checkpoint complex and activating the spindle checkpoint. Mutations in this gene have been associated with aneuploidy and several forms of cancer.

Gene names and symbols associated with BUB1

  • budding uninhibited by benzimidazoles 1 homolog (yeast) (BUB1) antibody
  • BUB1 mitotic checkpoint serine/threonine kinase (bub1) antibody
  • BUB1 mitotic checkpoint serine/threonine kinase (BUB1) antibody
  • BUB1 mitotic checkpoint serine/threonine kinase (Bub1) antibody
  • budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae) (Bub1) antibody
  • AL022991 antibody
  • Bub1a antibody
  • BUB1L antibody
  • C80208 antibody
  • D2Xrf87 antibody
  • hBUB1 antibody
  • xbub1 antibody

Protein level used designations for BUB1

BUB1 budding uninhibited by benzimidazoles 1 homolog , mitotic checkpoint serine/threonine-protein kinase BUB1 , budding uninhibited by benzimidazoles 1 , budding uninhibited by benzimidazoles 1 homolog , mitotic spindle checkpoint kinase , putative serine/threonine-protein kinase , mBUB1

GENE ID SPECIES
100064049 Equus caballus
459484 Pan troglodytes
780291 Xenopus (Silurana) tropicalis
699 Homo sapiens
296137 Rattus norvegicus
12235 Mus musculus
100682599 Canis lupus familiaris
514777 Bos taurus
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