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Butyrophilin, Subfamily 3, Member A1 Proteins (BTN3A1)

The butyrophilin (BTN) genes are a group of major histocompatibility complex (MHC)-associated genes that encode type I membrane proteins with 2 extracellular immunoglobulin (Ig) domains and an intracellular B30.2 (PRYSPRY) domain. Additionally we are shipping BTN3A1 Antibodies (46) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
BTN3A1 11119 O00481
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Top BTN3A1 Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Human Cells Human ECD,Fc Tag 100 μg Log in to see 16 Days
$437.80
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

BTN3A1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,

More Proteins for Butyrophilin, Subfamily 3, Member A1 (BTN3A1) Interaction Partners

Human Butyrophilin, Subfamily 3, Member A1 (BTN3A1) interaction partners

  1. These findings support intracellular sensing of prenyl pyrophosphates by BTN3A1 rather than extracellular presentation.

  2. Human gamma-delta T cells are activated by cytosolic interactions of BTN3A1 with soluble phosphoantigens and the cytoskeletal adaptor periplakin (show PPL Proteins).

  3. evidence that gene(s) on Chr6 in addition to BTN3A1 are mandatory for PAg (show PRDX1 Proteins)-mediated activation of Vgamma9Vdelta2 T cells.

  4. Ligand binding to the BTN3A1 B30.2 domain affects residues in the juxtamembrane region, suggesting ligand-induced conformational change.

  5. These studies demonstrate that internal sensing of changes in pAg (show PRDX1 Proteins) metabolite concentrations by BTN3A1 molecules is a critical step in Vgamma9Vdelta2 T cell detection of infection and tumorigenesis.

  6. BTN3A1 represents an antigen-presenting molecule required for the activation of Vgamma9Vdelta2 T cells.

  7. investigation of role of CD277 in activation/inactivation of T-lymphocytes: Data indicate that modulation of CD277 interaction (with agonists or blocking antibodies) with T-cell antigen receptor can modulate activation/inactivation of T-lymphocytes.

  8. BTN3A1 is necessary for Vgamma9Vdelta2 activation and begin to unravel the extracellular events that occur during stimulation through the Vgamma9Vdelta2 T cell receptor.

  9. CD277 triggering is not involved in CD16 (show CD16 Proteins)- or NKp46 (show NCR1 Proteins)-induced NK cell activation.

  10. Results point to a role for CD277 up-regulated by microenvironmental signals in the acquisition of a regulatory phenotype by ovarian tumor-associated myeloid cells.

BTN3A1 Protein Profile

Protein Summary

The butyrophilin (BTN) genes are a group of major histocompatibility complex (MHC)-associated genes that encode type I membrane proteins with 2 extracellular immunoglobulin (Ig) domains and an intracellular B30.2 (PRYSPRY) domain. Three subfamilies of human BTN genes are located in the MHC class I region: the single-copy BTN1A1 gene (MIM 601610) and the BTN2 (e.g., BTN2A1\\\\; MIM 613590) and BTN3 (e.g., BNT3A1) genes, which have undergone tandem duplication, resulting in 3 copies of each (summary by Smith et al., 2010

Gene names and symbols associated with BTN3A1

  • butyrophilin, subfamily 3, member A1 (BTN3A1)
  • BT3.1 protein
  • BTF5 protein
  • BTN3A1 protein
  • CD277 protein

Protein level used designations for BTN3A1

butyrophilin subfamily 3 member A1 , dJ45P21.3 (butyrophilin, subfamily 3, member A1) , butyrophilin, subfamily 3, member A1 , butyrophilin subfamily 3 member A1-like

GENE ID SPECIES
11119 Homo sapiens
462497 Pan troglodytes
100447925 Pongo abelii
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