anti-Butyrophilin-Like 2 (MHC Class II Associated) (BTNL2) Antibodies

Negative regulator of T-cell proliferation.. Additionally we are shipping BTNL2 Proteins (5) and BTNL2 Kits (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
BTNL2 547431 O70355
BTNL2 56244 Q9UIR0
BTNL2 309620  
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Showing 6 out of 7 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IF (p), IHC (p) Formalin-fixed and paraffin embedded human kidney labeled with Anti-BTNL2 Polyclonal Antibody, Unconjugated (ABIN1386835) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
Human Rabbit Un-conjugated WB Western blot analysis of BTNL2 expression in HepG2 (A), HL60 (B), mouse liver (C) whole cell lysates. 200 μL Log in to see 13 to 14 Days
Human Rabbit Un-conjugated IHC, WB   50 μL Log in to see 7 to 9 Days
Human Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of various cell lines, using BTNL2 antibody. 100 μL Log in to see 16 Days
Mouse Sheep Un-conjugated WB   50 μg Log in to see 2 to 3 Days
Human Rabbit Un-conjugated   100 μg Log in to see 11 to 16 Days

BTNL2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Mouse (Murine) ,

Human ,

Rat (Rattus)

More Antibodies against BTNL2 Interaction Partners

Mouse (Murine) Butyrophilin-Like 2 (MHC Class II Associated) (BTNL2) interaction partners

  1. Butyrophilin-like 2 modulates B7 costimulation to induce Foxp3 (show FOXP3 Antibodies) expression and regulatory T cell development in mature T cells.

  2. BTNL2 is overexpressed during both the asymptomatic and symptomatic phase of the Mdr1a (show ABCB4 Antibodies) knockout model of spontaneous colitis. Soluble BTNL2-Fc protein inhibits proliferation of murine T4 cells from the spleen, mesenteric lymph node, and Peyer's patch.

Human Butyrophilin-Like 2 (MHC Class II Associated) (BTNL2) interaction partners

  1. Two new signals were observed at genome-wide significance (P < 5 x 10-8), namely, rs7216064 (17q24.3, BPTF (show BPTF Antibodies)), for overall lung adenocarcinoma risk, and rs3817963 (6p21.3, BTNL2) which is specific to cases with EGFR (show EGFR Antibodies) mutations. In further sub-analyses by EGFR (show EGFR Antibodies) status, rs9387478 (ROS1 (show ROS1 Antibodies)/DCBLD1) and rs2179920 (HLA-DPB1 (show HLA-DPB1 Antibodies)) showed stronger estimated associations in EGFR (show EGFR Antibodies)-positive compared to EGFR (show EGFR Antibodies)-negative cases

  2. BTNL2 variant is associated with psoriasis.

  3. Butyrophilin-like 2, expressed at various levels by UM cells and macrophages, might interfere with the immune control of the tumor. Butyrophilin-like 2 variants showed highly variable frequencies among ethnically related cohorts. There was no enrichment of BTNL2 variants in patients with UM compared with control patients.

  4. BTNL2 G16071A gene polymorphism may as a likelihood factor contributed to granulomatous disease susceptibility, especially increasing the sarcoidosis susceptibility. In addition, the polymorphism may be greatly associated with likelihood of granulomatous diseases among Caucasians.

  5. BTNL2 may have an inhibitory effect on FOXP3 (show FOXP3 Antibodies)(+) T cell proliferation, especially in patients homozygous for the risk alleles.

  6. genetic mutations within or around BTNL2 (rs3763313, rs9268494, rs9268492 and rs9268402) could alter susceptibility to grade IV of dilated cardiomyopathy in a Chinese population

  7. Results confirm the association of BTNL2 rs2076530SNP with the susceptibility to develop sarcoidosis, but not with an increased risk of cancer in these patients.

  8. BTNL2 rs2076530 polymorphism contributes to the risk of sarcoidosis

  9. Two independent loci near BTNL2 (rs9461741) and HLA-B (rs2922994) in the HLA region significantly associated with Marginal Zone B-Cell Lymphoma risk.

  10. The association of the rare variant p.G454C in BTNL2 reached genome-wide significance, and was independent of the known common risk variants for IBD in the HLA region in both a conditional and haplotype analysis

BTNL2 Antigen Profile

Protein Summary

Negative regulator of T-cell proliferation.

Gene names and symbols associated with BTNL2

  • butyrophilin-like 2 (MHC class II associated) (BTNL2) antibody
  • butyrophilin-like 2 (Btnl2) antibody
  • butyrophilin-like 2 (MHC class II associated) (Btnl2) antibody
  • BTL-II antibody
  • Btl2 antibody
  • BTLN2 antibody
  • BTNL2 antibody
  • Gm315 antibody
  • HSBLMHC1 antibody
  • Ng9 antibody
  • SS2 antibody

Protein level used designations for BTNL2

butyrophilin-like protein 2 , butyrophilin-like 2 (MHC class II associated) , butyrophilin-like protein 2-like , butyrophylin-like MHC class II associated

481730 Canis lupus familiaris
789224 Bos taurus
505077 Bos taurus
745506 Pan troglodytes
100051881 Equus caballus
100158014 Sus scrofa
100348151 Oryctolagus cuniculus
100441854 Pongo abelii
547431 Mus musculus
56244 Homo sapiens
309620 Rattus norvegicus
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