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CCR1 encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Additionally we are shipping CCR1 Kits (16) and CCR1 Proteins (6) and many more products for this protein.
Showing 10 out of 90 products:
Human Monoclonal CCR1 Primary Antibody for FACS - ABIN1105988
Rosen: Homing in on L-selectin. in Journal of immunology (Baltimore, Md. : 1950) 2006
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Human Monoclonal CCR1 Primary Antibody for Func, ELISA - ABIN2656989
Ayehunie, Garcia-Zepeda, Hoxie, Horuk, Kupper, Luster, Ruprecht: Human immunodeficiency virus-1 entry into purified blood dendritic cells through CC and CXC chemokine coreceptors. in Blood 1997
Show all 7 references for ABIN2656989
Human Monoclonal CCR1 Primary Antibody for FACS, ELISA - ABIN2657064
Bednar, Song, Bardi, Cornwell, Rogers: Cross-desensitization of CCR1, but not CCR2, following activation of the formyl peptide receptor FPR1. in Journal of immunology (Baltimore, Md. : 1950) 2014
Show all 7 references for ABIN2657064
Cow (Bovine) Polyclonal CCR1 Primary Antibody for EIA, IHC (fro) - ABIN492850
Tran, Miller: Chemokine receptors: signposts to brain development and disease. in Nature reviews. Neuroscience 2003
Show all 3 references for ABIN492850
CCL15-positive primary colorectal cancers recruited approximately 2.2 times more numbers of CCR1(+) cells.
The residues on the N-loop and beta-sheets of MIP-1a (show CCL3 Antibodies) are close to both CCR1 and CCR5 (show CCR5 Antibodies), and those in the C-terminal helix region are close to CCR5 (show CCR5 Antibodies).
Results highlight the potential role of CCR (show POR Antibodies) genes in narcolepsy and support the hypothesis that patients with narcolepsy have impaired immune function.
CCR1, KLRC4 (show KLRC4 Antibodies), IL12A (show IL12A Antibodies)-AS1 (show PTGDR Antibodies), STAT4 (show STAT4 Antibodies), and ERAP1 (show ERAP1 Antibodies) are bona fide susceptibility genes for Behcet's disease.
This study reveled that CCR1 having a central role in the bipolar disease and schizophrenia manifestation.
Identifying bias in CCR1 antagonists using radiolabelled binding, receptor internalization, beta-arrestin translocation and chemotaxis assays
These results suggest that increased CC-chemokine receptor expression may play a role in the pathogenesis of adenomyosis.
Our results confirm the strong influence of previous immunity in subsequent dengue infections, and confer a possible pathogenic role to CCR1 and CCL3 (show CCL3 Antibodies) in dengue disease and a possible protective role for CCL5 (show CCL5 Antibodies), probably through CCR5 (show CCR5 Antibodies) interaction.
cross-desensitization of CCR1 by FPR1 (show FPR1 Antibodies) was associated with CCR1 phosphorylation and moderate reduction of CCR1 cell-surface expression. In contrast, CCR2 (show CCR2 Antibodies) was not phosphorylated or internalized after FPR1 (show FPR1 Antibodies) activation.
Data suggest that CCL13 binds to several chemokine receptors (CCR1, CCR2, and CCR3), allowing CCL13 to elicit different effects on its target cells of the immune system. CCL13/CCR1 signal transduction is key step in asthma progression. [REVIEW]
Inhibition of CCR1, the distal part of this signaling relay, may have a therapeutic impact in metastatic disease with lower toxicity than blocking upstream targets.
Data indicate that deletion or inhibition of CC chemokine receptor 1 (CCR1) decreases pain responses.
CCR1-mediated accumulation of myeloid cells in the liver microenvironment promotes mouse colon cancer metastasis.
CCR1 is required for recruitment of neutrophils during respiratory infection with modified vaccinia virus Ankara.
This study demonstrates a Tpl2 (show MAP3K8 Antibodies)-dependent mechanism for macrophage expression of select chemokine (show CCL1 Antibodies) receptors.
Ccr1 plays a critical role in the recruitment of T and mononuclear phagocyte cells to inflamed kidneys of NZB/W mice, which in turn contribute to the progression of renal injury.
CCR1.beta-arrestin-2 (show ARRB2 Antibodies) complex may be related to a potential scavenging function of the receptor, which may be important for maintenance of chemokine (show CCL1 Antibodies) gradients and receptor responsiveness in complex fields of chemokines during inflammation.
CCR1 expression by both hematopoietic and nonhematopoietic cells favors tumor aggressiveness and liver cancer metastasis development.
findings show that CCR1 is pivotal for bone remodeling induced by mechanical loading during orthodontic tooth movement and these actions depend, at least in part, on CCL3 (show CCL3 Antibodies)
neutrophil Ccr1 amplifies late renal immunopathology and increases mortality in invasive candidiasis by mediating excessive recruitment of neutrophils from the blood to the target organ.
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p.
, C-C chemokine receptor type 1
, LD78 receptor
, RANTES receptor
, macrophage inflammatory protein 1-alpha receptor
, macrophage inflammatory protein-1 alpha receptor
, MIP-1 alpha R
, MIP-1 alphaR
, chemokine (C-C) receptor 1
, chemokine receptor