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C-C Chemokine Receptor Type 1 Proteins (CCR1)

CCR1 encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Additionally we are shipping CCR1 Antibodies (90) and CCR1 Kits (16) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CCR1 1230 P32246
Rat CCR1 CCR1 57301  
CCR1 12768 P51675
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Top CCR1 Proteins at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
Yeast Arabidopsis thaliana His tag   1 mg Log in to see 56 to 66 Days
$3,157.00
Details
HOST_Wheat germ Human Un-conjugated   2 μg Log in to see 9 Days
$491.43
Details
HOST_Wheat germ Human GST tag   10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   5 applications Log in to see 1 to 2 Days
$312.71
Details

CCR1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for C-C Chemokine Receptor Type 1 (CCR1) Interaction Partners

Human C-C Chemokine Receptor Type 1 (CCR1) interaction partners

  1. CCL15-positive primary colorectal cancers recruited approximately 2.2 times more numbers of CCR1(+) cells.

  2. The residues on the N-loop and beta-sheets of MIP-1a are close to both CCR1 and CCR5, and those in the C-terminal helix region are close to CCR5.

  3. Results highlight the potential role of CCR (show POR Proteins) genes in narcolepsy and support the hypothesis that patients with narcolepsy have impaired immune function.

  4. CCR1, KLRC4 (show KLRC4 Proteins), IL12A (show IL12A Proteins)-AS1 (show PTGDR Proteins), STAT4 (show STAT4 Proteins), and ERAP1 (show ERAP1 Proteins) are bona fide susceptibility genes for Behcet's disease.

  5. This study reveled that CCR1 having a central role in the bipolar disease and schizophrenia manifestation.

  6. Identifying bias in CCR1 antagonists using radiolabelled binding, receptor internalization, beta-arrestin translocation and chemotaxis assays

  7. These results suggest that increased CC-chemokine receptor expression may play a role in the pathogenesis of adenomyosis.

  8. Our results confirm the strong influence of previous immunity in subsequent dengue infections, and confer a possible pathogenic role to CCR1 and CCL3 in dengue disease and a possible protective role for CCL5, probably through CCR5 interaction.

  9. cross-desensitization of CCR1 by FPR1 (show FPR1 Proteins) was associated with CCR1 phosphorylation and moderate reduction of CCR1 cell-surface expression. In contrast, CCR2 (show CCR2 Proteins) was not phosphorylated or internalized after FPR1 (show FPR1 Proteins) activation.

  10. Data suggest that CCL13 binds to several chemokine receptors (CCR1, CCR2, and CCR3), allowing CCL13 to elicit different effects on its target cells of the immune system. CCL13/CCR1 signal transduction is key step in asthma progression. [REVIEW]

Mouse (Murine) C-C Chemokine Receptor Type 1 (CCR1) interaction partners

  1. Inhibition of CCR1, the distal part of this signaling relay, may have a therapeutic impact in metastatic disease with lower toxicity than blocking upstream targets.

  2. Data indicate that deletion or inhibition of CC chemokine receptor 1 (CCR1) decreases pain responses.

  3. CCR1-mediated accumulation of myeloid cells in the liver microenvironment promotes mouse colon cancer metastasis.

  4. CCR1 is required for recruitment of neutrophils during respiratory infection with modified vaccinia virus Ankara.

  5. This study demonstrates a Tpl2 (show MAP3K8 Proteins)-dependent mechanism for macrophage expression of select chemokine (show CCL1 Proteins) receptors.

  6. Ccr1 plays a critical role in the recruitment of T and mononuclear phagocyte cells to inflamed kidneys of NZB/W mice, which in turn contribute to the progression of renal injury.

  7. CCR1.beta-arrestin-2 (show ARRB2 Proteins) complex may be related to a potential scavenging function of the receptor, which may be important for maintenance of chemokine (show CCL1 Proteins) gradients and receptor responsiveness in complex fields of chemokines during inflammation.

  8. CCR1 expression by both hematopoietic and nonhematopoietic cells favors tumor aggressiveness and liver cancer metastasis development.

  9. findings show that CCR1 is pivotal for bone remodeling induced by mechanical loading during orthodontic tooth movement and these actions depend, at least in part, on CCL3 (show CCL3 Proteins)

  10. neutrophil Ccr1 amplifies late renal immunopathology and increases mortality in invasive candidiasis by mediating excessive recruitment of neutrophils from the blood to the target organ.

CCR1 Protein Profile

Protein Summary

This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p.

Gene names and symbols associated with CCR1

  • chemokine (C-C motif) receptor 1 (CCR1)
  • chemokine (C-C motif) receptor 1 (Ccr1)
  • CD191 protein
  • CKR-1 protein
  • CKR1 protein
  • Cmkbr1 protein
  • HM145 protein
  • Mip-1a-R protein
  • MIP1aR protein
  • SCYAR1 protein

Protein level used designations for CCR1

C-C CKR-1 , C-C chemokine receptor type 1 , CC-CKR-1 , CCR-1 , LD78 receptor , MIP-1alpha-R , RANTES receptor , RANTES-R , macrophage inflammatory protein 1-alpha receptor , macrophage inflammatory protein-1 alpha receptor , MIP-1 alpha R , MIP-1 alphaR , chemokine (C-C) receptor 1 , chemokine receptor

GENE ID SPECIES
1230 Homo sapiens
57301 Rattus norvegicus
12768 Mus musculus
574188 Macaca mulatta
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