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CLEC2A belongs to the CLEC2 family of activation-induced, natural killer gene complex-encoded C-type lectin-like receptors (Spreu et al., 2007. Additionally we are shipping C-Type Lectin Domain Family 2, Member A Proteins (3) and many more products for this protein.
Showing 10 out of 35 products:
Human Polyclonal CLEC2A Primary Antibody for EIA, WB - ABIN951564
Spreu, Kuttruff, Stejfova, Dennehy, Schittek, Steinle: Interaction of C-type lectin-like receptors NKp65 and KACL facilitates dedicated immune recognition of human keratinocytes. in Proceedings of the National Academy of Sciences of the United States of America 2010
Show all 5 references for ABIN951564
Human Polyclonal CLEC2A Primary Antibody for EIA, IF - ABIN1449942
Huarte, Cubillos-Ruiz, Nesbeth, Scarlett, Martinez, Engle, Rigby, Pioli, Guyre, Conejo-Garcia: PILAR is a novel modulator of human T-cell expansion. in Blood 2008
PDGF (show PDGFA Antibodies) upregulates the expression of CLEC-2 (show CLEC1B Antibodies) on dendritic cells to induce T regulatory cells.
Key residues at the membrane-distal surface of KACL, but not glycosylation, determine the functional interaction of the keratinocyte-specific C-type lectin (show MBL2 Antibodies)-like receptor KACL with its high-affinity receptor NKp65 (show KLRF2 Antibodies)
CLEC-2 (show CLEC1B Antibodies), unlike platelet ITAM receptors, is not regulated by proteolysis and can be used to monitor platelet-derived microparticles
Keratinocytes express KACL and are capable of stimulating NKp65 (show KLRF2 Antibodies)-expressing cells in a KACL-dependent manner.
T-cell PILAR signaling through CD161 (show KLRB1 Antibodies) supports CD3 (show CD3 Antibodies) antibody-dependent and antigen-specific T-cell proliferation by increasing the expression of antiapoptotic Bcl-xL (show BCL2L1 Antibodies) and induces secretion of T helper type 1 cytokines
CLEC-2 (show CLEC1B Antibodies) is the receptor for podoplanin (show PDPN Antibodies), a sialoglycoprotein implicated in tumor-induced platelet aggregation and tumor metastasis[review]
CLEC2A belongs to the CLEC2 family of activation-induced, natural killer gene complex-encoded C-type lectin-like receptors (Spreu et al., 2007
C-type lectin domain family 2 member A
, keratinocyte-associated C-type lectin
, proliferation-induced lymphocyte-associated receptor