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C-Type Lectin Domain Family 2, Member A Proteins (CLEC2A)

CLEC2A belongs to the CLEC2 family of activation-induced, natural killer gene complex-encoded C-type lectin-like receptors (Spreu et al., 2007 [PubMed 18046548]).[supplied by OMIM, May 2008].. Additionally we are shipping C-Type Lectin Domain Family 2, Member A Antibodies (26) and C-Type Lectin Domain Family 2, Member A Kits (9) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CLEC2A 387836 Q6UVW9
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Top C-Type Lectin Domain Family 2, Member A Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

CLEC2A Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,

More Proteins for C-Type Lectin Domain Family 2, Member A (CLEC2A) Interaction Partners

Human C-Type Lectin Domain Family 2, Member A (CLEC2A) interaction partners

  1. PDGF (show PDGFA Proteins) upregulates the expression of CLEC-2 (show CLEC1B Proteins) on dendritic cells to induce T regulatory cells.

  2. Key residues at the membrane-distal surface of KACL, but not glycosylation, determine the functional interaction of the keratinocyte-specific C-type lectin (show MBL2 Proteins)-like receptor KACL with its high-affinity receptor NKp65 (show KLRF2 Proteins)

  3. CLEC-2 (show CLEC1B Proteins), unlike platelet ITAM receptors, is not regulated by proteolysis and can be used to monitor platelet-derived microparticles

  4. Keratinocytes express KACL and are capable of stimulating NKp65 (show KLRF2 Proteins)-expressing cells in a KACL-dependent manner.

  5. T-cell PILAR signaling through CD161 (show KLRB1 Proteins) supports CD3 (show CD3 Proteins) antibody-dependent and antigen-specific T-cell proliferation by increasing the expression of antiapoptotic Bcl-xL (show BCL2L1 Proteins) and induces secretion of T helper type 1 cytokines

  6. CLEC-2 (show CLEC1B Proteins) is the receptor for podoplanin (show PDPN Proteins), a sialoglycoprotein implicated in tumor-induced platelet aggregation and tumor metastasis[review]

C-Type Lectin Domain Family 2, Member A (CLEC2A) Protein Profile

Protein Summary

CLEC2A belongs to the CLEC2 family of activation-induced, natural killer gene complex-encoded C-type lectin-like receptors (Spreu et al., 2007

Gene names and symbols associated with CLEC2A

  • C-type lectin domain family 2, member A (CLEC2A)
  • KACL protein
  • PILAR protein
  • UNQ5792 protein

Protein level used designations for CLEC2A

C-type lectin domain family 2 member A , INPE5792 , keratinocyte-associated C-type lectin , proliferation-induced lymphocyte-associated receptor

GENE ID SPECIES
387836 Homo sapiens
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