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C-Type Lectin Domain Family 4, Member M Proteins

(C-Type Lectin Domain Family 4, Member M (CLEC4M))

This gene encodes a transmembrane receptor and is often referred to as L-SIGN because of its expression in the endothelial cells of the lymph nodes and liver. The encoded protein is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses, with a large impact on public health. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization which allows the receptor to bind multivalent ligands with high avidity. Variations in the number of 23 amino acid repeats in the neck domain of this protein are common and have a significant impact on ligand binding ability. This gene is closely related in terms of both sequence and function to a neighboring gene (GeneID 30835\; often referred to as DC-SIGN or CD209). DC-SIGN and L-SIGN differ in their ligand-binding properties and distribution. Alternative splicing results in multiple variants.[provided by RefSeq, Feb 2009].

recommended

C-Type Lectin Domain Family 4, Member M (CLEC4M) (AA 285-394) protein (GST tag) (ABIN1349664)

CLEC4M Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP

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recommended

C-Type Lectin Domain Family 4, Member M (CLEC4M) (AA 71-399) protein (His tag) (ABIN3091840)

Crystallography grade CLEC4M Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys

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recommended

C-Type Lectin Domain Family 4, Member M (CLEC4M) (AA 1-399) protein (Strep Tag) (ABIN3118083)

Crystallography grade CLEC4M Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA

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C-Type Lectin Domain Family 4, Member M Proteins by Grade

Find C-Type Lectin Domain Family 4, Member M Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

C-Type Lectin Domain Family 4, Member M Proteins by Origin

Find C-Type Lectin Domain Family 4, Member M Proteins for a variety of species such as anti-Human C-Type Lectin Domain Family 4, Member M, anti-Chimpanzee C-Type Lectin Domain Family 4, Member M. The species listed below are among those available. Click on a link to go to the corresponding products.

C-Type Lectin Domain Family 4, Member M Proteins by Source

Here you will find C-Type Lectin Domain Family 4, Member M Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

C-Type Lectin Domain Family 4, Member M Proteins by Protein Type

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C-Type Lectin Domain Family 4, Member M Proteins by Application

Find C-Type Lectin Domain Family 4, Member M Proteins validated for a specific application such as ELISA, WB, SDS, AbP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular C-Type Lectin Domain Family 4, Member M Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

C-Type Lectin Domain Family 4, Member M (CLEC4M) (AA 285-394) protein (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1349664

Quantity 10 μg

Datasheet Datasheet

C-Type Lectin Domain Family 4, Member M (CLEC4M) (AA 71-399) protein (His tag)

Reactivity Human

Source Insect Cells

Validations

Cat. No. ABIN3091840

Quantity 1 mg

Datasheet Datasheet

C-Type Lectin Domain Family 4, Member M (CLEC4M) (AA 1-399) protein (Strep Tag)

Reactivity Human

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3118083

Quantity 1 mg

Datasheet Datasheet

C-Type Lectin Domain Family 4, Member M (CLEC4M) (AA 71-399) protein (His-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN7504305

Quantity 100 μg

Datasheet Datasheet

C-Type Lectin Domain Family 4, Member M (CLEC4M) (AA 71-399) Protein

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN7504304

Quantity 100 μg

Datasheet Datasheet

C-Type Lectin Domain Family 4, Member M (CLEC4M) (AA 242-399) protein (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7413766

Quantity 100 μg

Datasheet Datasheet

C-Type Lectin Domain Family 4, Member M (CLEC4M) protein (Fc Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN7194490

Quantity 100 μg

Datasheet Datasheet

C-Type Lectin Domain Family 4, Member M (CLEC4M) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2713616

Quantity 20 μg

Datasheet Datasheet

C-Type Lectin Domain Family 4, Member M (CLEC4M) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2716811

Quantity 20 μg

Datasheet Datasheet

C-Type Lectin Domain Family 4, Member M (CLEC4M) (AA 71-445) protein (His tag)

Reactivity Chimpanzee

Source Yeast

Validations

Cat. No. ABIN1636713

Quantity 1 mg

Datasheet Datasheet

Aliases for C-Type Lectin Domain Family 4, Member M Proteins

C-type lectin domain family 4 member M (CLEC4M) Proteins
CD209B Proteins
CD209L Proteins
CD299 Proteins
DC-SIGN2 Proteins
DC-SIGNR Proteins
DCSIGNR Proteins
HP10347 Proteins
L-SIGN Proteins
LSIGN Proteins

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C-Type Lectin Domain Family 4, Member M Proteins by Grade

C-Type Lectin Domain Family 4, Member M Proteins by Origin

C-Type Lectin Domain Family 4, Member M Proteins by Source

C-Type Lectin Domain Family 4, Member M Proteins by Protein Type

C-Type Lectin Domain Family 4, Member M Proteins by Application

Popular C-Type Lectin Domain Family 4, Member M Proteins

Aliases for C-Type Lectin Domain Family 4, Member M Proteins

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