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CAMP Responsive Element Binding Protein 3-Like 1 Proteins (CREB3L1)

Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Additionally we are shipping CAMP Responsive Element Binding Protein 3-Like 1 Antibodies (70) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CREB3L1 90993 Q96BA8
CREB3L1 26427 Q9Z125
Rat CREB3L1 CREB3L1 362165 Q66HA2
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Top CAMP Responsive Element Binding Protein 3-Like 1 Proteins at antibodies-online.com

Showing 7 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Cells Human His tag 100 μg Log in to see 16 Days
$437.80
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 9 to 11 Days
$229.85
Details

CREB3L1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
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Mouse (Murine) ,
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More Proteins for CAMP Responsive Element Binding Protein 3-Like 1 (CREB3L1) Interaction Partners

Human CAMP Responsive Element Binding Protein 3-Like 1 (CREB3L1) interaction partners

  1. Our data further strengthens the role for CREB3L1 as a metastasis suppressor in breast cancer and demonstrates that epigenetic silencing is a major regulator of the loss of CREB3L1 expression

  2. CREB3L1 was expressed in 19% of RCC, which is generally resistant to doxorubicin, but in 70% of diffuse (show XRCC1 Proteins) large B-cell lymphoma that is sensitive to doxorubicin.

  3. CREB3L1 mRNA expression is downregulated in human bladder cancer.CREB3L1 is epigenetically silenced in human bladder cancer facilitating tumor cell spreading and migration in vitro.

  4. Cleavage of CREB3L1 releases its NH2-terminal domain from membranes, allowing it to enter the nucleus where it binds to Smad4 (show SMAD4 Proteins) to activate transcription of genes encoding proteins required for assembly of collagen-containing extracellular matrix.

  5. CREB3L1 expression may be a useful biomarker in identifying cancer cells sensitive to doxorubicin.

  6. Case Reports: genetically confirmed primary renal sclerosing epithelioid fibrosarcoma with EWSR1 (show EWSR1 Proteins)-CREB3L1 gene fusion.

  7. Case Report: low-grade fibromyxoid sarcoma of the kidney found to harbor the EWSR1 (show EWSR1 Proteins)-CREB3L1 gene fusion.

  8. EWSR1 (show EWSR1 Proteins)-CREB3L1 gene fusions are predominant over FUS (show FUS Proteins) and CREB3L2 (show CREB3L2 Proteins) rearrangements in pure sclerosing epithelioid fibrosarcoma.

  9. CREB3L1 plays an important role in suppressing tumorigenesis and that loss of expression is required for the development of a metastatic phenotype.

  10. Fbxw7 (show FBXW7 Proteins) controls osteogenesis and chondrogenesis by targeting OASIS and BBF2H7 (show CREB3L2 Proteins), respectively, for degradation.

Mouse (Murine) CAMP Responsive Element Binding Protein 3-Like 1 (CREB3L1) interaction partners

  1. OASIS affects the expression of HIF-1alpha (show HIF1A Proteins) target genes through the protein interaction with HIF-1alpha (show HIF1A Proteins), and that OASIS-HIF-1alpha (show HIF1A Proteins) complexes may play essential roles in angiogenesis during bone development.

  2. Higher levels of CREB3L1 protein are correlated with increased doxorubicin sensitivity of xenograft RCC (show XRCC1 Proteins) tumors

  3. Increased susceptibility to dextran sulfate sodium-induced colitis in the endoplasmic reticulum stress transducer OASIS deficient mice.

  4. We conclude that OASIS functions as an anti-regenerative transcription factor by establishing a non-permissive microenvironment to regenerating axons

  5. Fbxw7 (show FBXW7 Proteins) controls osteogenesis and chondrogenesis by targeting OASIS and BBF2H7 (show CREB3L2 Proteins), respectively, for degradation.

  6. Gliosis-specific transcription factor OASIS coincides with proteoglycan core protein (show EPYC Proteins) genes in the glial scar and inhibits neurite outgrowth.

  7. Findings demonstrate a novel mechanism by which OASIS and its associated family members are modulated by the unfolded protein response to finely control astrocyte differentiation.

  8. OASIS plays crucial roles in promoting the differentiation of early goblet cells to mature goblet cells in the large intestine.

  9. OASIS may play a role in bone formation through the expression of type I collagen and the secretion of bone matrix proteins in fracture healing.

  10. OASIS regulates skeletal development by osteoblast-dependent and -independent mechanisms.

CAMP Responsive Element Binding Protein 3-Like 1 (CREB3L1) Protein Profile

Protein Summary

Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system. May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE (By similarity).

Gene names and symbols associated with CREB3L1

  • cAMP responsive element binding protein 3-like 1 (CREB3L1)
  • cAMP responsive element binding protein 3-like 1 (LOC100345475)
  • cAMP responsive element binding protein 3-like 1 (Creb3l1)
  • CREB3L1 protein
  • Oasis protein

Protein level used designations for CREB3L1

cAMP responsive element binding protein 3-like 1 , cyclic AMP-responsive element-binding protein 3-like protein 1-like , BBF-2 homolog , cAMP-responsive element-binding protein 3-like protein 1 , cyclic AMP-responsive element-binding protein 3-like protein 1 , old astrocyte specifically-induced substance , old astrocyte specifically induced substance

GENE ID SPECIES
423198 Gallus gallus
451704 Pan troglodytes
100345475 Oryctolagus cuniculus
100406635 Callithrix jacchus
100432292 Pongo abelii
100516663 Sus scrofa
100594080 Nomascus leucogenys
90993 Homo sapiens
483636 Canis lupus familiaris
513105 Bos taurus
26427 Mus musculus
362165 Rattus norvegicus
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