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anti-CASP8 Associated Protein 2 (CASP8AP2) Antibodies

This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Additionally we are shipping FLASH Kits (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CASP8AP2 9994 Q9UKL3
CASP8AP2 26885 Q9WUF3
CASP8AP2 313128  
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Top anti-FLASH Antibodies at antibodies-online.com

Showing 10 out of 47 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-CASP8AP2 Antibody Titration: 0.2-1 ug/mlPositive Control: Hela cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, IF, WB Immunocytochemistry of FLASH in HeLa cells with AP30339PU-N FLASH antibody at 10 μg/ml. Western blot analysis of FLASH in HeLa whole cell lysate with AP30339PU-N FLASH antibody at 0.5 μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated IF, IHC (p), WB 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated ICC, IHC (p), WB Human Skeletal Muscle (formalin-fixed, paraffin-embedded) stained with CASP8AP2 antibody ABIN214304 at 10 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 8 to 10 Days
$419.83
Details
Human Rabbit Un-conjugated WB   100 μg Log in to see 8 to 10 Days
$419.83
Details
Human Rabbit Un-conjugated WB CASP8AP2 antibody used at 0.2-1 ug/ml to detect target protein. 50 μg Log in to see 7 to 9 Days
$473.93
Details
Mouse Rabbit Un-conjugated ELISA, WB   50 μL Log in to see 8 to 10 Days
$566.50
Details

CASP8AP2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , , ,


Mouse (Murine) ,


Rat (Rattus) ,


Top referenced anti-FLASH Antibodies

  1. Cow (Bovine) Polyclonal FLASH Primary Antibody for WB - ABIN2784233 : Lee, Pi, Lee: Buffer optimization for high resolution of human lung cancer tissue proteins by two-dimensional gel electrophoresis. in Biotechnology letters 2008 (PubMed)
    Show all 2 references for ABIN2784233

  2. Human Polyclonal FLASH Primary Antibody for EIA, IF - ABIN499842 : Imai, Kimura, Murakami, Yajima, Sakamaki, Yonehara: The CED-4-homologous protein FLASH is involved in Fas-mediated activation of caspase-8 during apoptosis. in Nature 1999 (PubMed)

More Antibodies against FLASH Interaction Partners

Human CASP8 Associated Protein 2 (CASP8AP2) interaction partners

  1. Our results indicate that the APAF1 (show APAF1 Antibodies), BAX (show BAX Antibodies), and FLASH genes not only harbor frameshift mutations but also demonstrate mutational ITH, which together might play a role in the tumorigenesis of CRC (show CALR Antibodies) with MSI (show MSI1 Antibodies)-H by affecting the apoptosis of cancer cells.

  2. High-quality solution NMR structures of three homeodomains from human proteins ALX4 (show ALX4 Antibodies), ZHX1 (show ZHX1 Antibodies) and CASP8AP2 were solved.

  3. the predictive values regarding low expressions of H2AFZ (show H2AFZ Antibodies) and CASP8AP2 and high white blood cell count suggest that these features could help to identify more accurately patients at greater risk of relapse.

  4. ARS2 (show SRRT Antibodies) and CASP8AP2 expressions can precisely predict high-risk of relapse and ALL prognosis.

  5. The conserved C-terminal domain shared by FLASH, YARP, and Mute recognizes the C-terminal sequence of NPAT (show NPAT Antibodies) orthologues, thus acting as a signal targeting proteins to histone locus bodies.

  6. Data suggest that SUMO targets FLASH for proteasome-dependent degradation, which is associated with recruitment of FLASH to PML (show PML Antibodies) bodies.

  7. Hypermethylation of two CpG sites upstream of CASP8AP2 promoter influences gene expression and treatment outcome in childhood acute lymphoblastic leukemia.

  8. FLASH/Lsm11 (show LSM11 Antibodies) complex bind a unique combination of polyadenylation factors

  9. These data demonstrate that methylation within the Casp8AP2 promoter correlates with the development of drug resistance and might serve as a biomarker and treatment target for drug resistance in cancer cells.

  10. FLASH knockdown in HT1080 (show CDC123 Antibodies) mutant cells defective in p53 (show TP53 Antibodies) did not significantly accelerate Fas (show FAS Antibodies) mediated apoptosis indicating that the effect was dependent on functional p53 (show TP53 Antibodies).

Mouse (Murine) CASP8 Associated Protein 2 (CASP8AP2) interaction partners

  1. the functional interaction of E2A (show TCF3 Antibodies) and FLASH play an important role in cell proliferation and cellular senescence via regulation of p21 (show D4S234E Antibodies) expression in experimental glomerulonephritis.

  2. Data suggest that SUMO targets FLASH for proteasome-dependent degradation, which is associated with recruitment of FLASH to PML (show PML Antibodies) bodies.

FLASH (CASP8AP2) Antigen Profile

Protein Summary

This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein.

Gene names and symbols associated with CASP8AP2

  • caspase 8 associated protein 2 (CASP8AP2) antibody
  • CASP8 associated protein 2 (casp8ap2) antibody
  • CASP8 associated protein 2 (CASP8AP2) antibody
  • CASP8 associated protein 2 (LOC100232114) antibody
  • caspase 8 associated protein 2 (Casp8ap2) antibody
  • AA387232 antibody
  • CASP8AP2 antibody
  • CED-4 antibody
  • D4Ertd659e antibody
  • fc74h10 antibody
  • FLASH antibody
  • mKIAA1315 antibody
  • RIP25 antibody
  • wu:fc74h10 antibody
  • zgc:113449 antibody

Protein level used designations for CASP8AP2

CASP8 associated protein 2 , caspase 8 associated protein 2 , CASP8-associated protein 2-like , CASP8-associated protein 2 , FLASH homolog RIP25 , FLICE associated huge , FLICE-associated huge protein , human FLASH

GENE ID SPECIES
421810 Gallus gallus
472070 Pan troglodytes
541521 Danio rerio
100065766 Equus caballus
100232114 Taeniopygia guttata
702294 Macaca mulatta
100342805 Oryctolagus cuniculus
100401726 Callithrix jacchus
100445558 Pongo abelii
100523759 Sus scrofa
9994 Homo sapiens
26885 Mus musculus
481921 Canis lupus familiaris
505138 Bos taurus
313128 Rattus norvegicus
Selected quality suppliers for anti-FLASH (CASP8AP2) Antibodies
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