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The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. Additionally we are shipping CEBPA Antibodies (140) and CEBPA Proteins (11) and many more products for this protein.
Showing 10 out of 31 products:
Human CEBPA ELISA Kit for Sandwich ELISA - ABIN414603
Seipel, Marques, Bozzini, Meinken, Mueller, Pabst: Inactivation of the p53-KLF4-CEBPA Axis in Acute Myeloid Leukemia. in Clinical cancer research : an official journal of the American Association for Cancer Research 2016
The efficient repression of E2F (show E2F1 ELISA Kits) dependent S-phase genes and the activation of differentiation genes reside in the balanced DNA binding capacity of C/EBP alpha.
we are the first to identify that miR (show MLXIP ELISA Kits)-381 suppresses C/EBPalpha-dependent Cx43 (show GJA1 ELISA Kits) expression in breast cancer cells. The miR (show MLXIP ELISA Kits)-381-C/EBPalpha-Cx43 (show GJA1 ELISA Kits) axis might be a useful diagnostic and therapeutic target of metastatic breast cancer
results suggested that C/EBPalpha-saRNA successfully inhibited HCC (show FAM126A ELISA Kits) metastasis by inhibiting EGFR (show EGFR ELISA Kits)/beta-catenin (show CTNNB1 ELISA Kits) signaling pathway mediated EMT (show ITK ELISA Kits) in vitro and in vivo
These results suggest that genetic predisposition to higher IL-6 (show IL6 ELISA Kits) production is associated with increased risk to HBV infection and hepatic inflammation, which might be due to C/EBPalpha-mediated regulatory effect on Th17 and Treg responses.
the present study demonstrated that suppression of C/EBPa P42 (show EPB42 ELISA Kits) induced by PI3K (show PIK3CA ELISA Kits)/Akt (show AKT1 ELISA Kits)/mTOR (show FRAP1 ELISA Kits) inhibition impaired the differentiation and ATRA sensitivity of acute promyelocytic leukemia (show PML ELISA Kits) cells.
Data uncover GCN5 (show KAT2A ELISA Kits) as a negative regulator of C/EBPalpha and demonstrate the importance of C/EBPalpha acetylation in myeloid differentiation.
younger age, presence of mirror repeats, and high CEBPA expression level in relation to potential topo II-sites, might affect the incidence of B-ZIP in-frame CNVs through aberrant recombination-mediated DNA repair mechanisms.
Reprogramming human B cells into induced pluripotent stem cells and is enhanced by C/EBPa.
this is the first report on the regulation mechanism of SIRT7 (show SIRT7 ELISA Kits) gene, in which, HDAC3 (show HDAC3 ELISA Kits) collaborated with C/EBPalpha to occupy its responding element in the upstream region of SIRT7 (show SIRT7 ELISA Kits) gene and repressed its expression in human cells.
Results show that CEBPA in combinations with FLT3 (show FLT3 ELISA Kits) and NPM1 (show NPM1 ELISA Kits) genotype confer favourable prognosis in AML (show RUNX1 ELISA Kits)
Cebpa enhancers and silencers in a transcriptional model have roles in hematopoietic lineage specification
Data show that CCAAT-enhancer-binding protein-alpha (C/EBPalpha) directly regulates Kruppel-like factor 4 (Klf4 (show KLF4 ELISA Kits)) expression and increasing the levels of histone demethylase (show MBD2 ELISA Kits) Lsd1 (show KDM1A ELISA Kits) and transcription factor Brd4 (show BRD4 ELISA Kits) in B cell.
The findings demonstrate a critical role for the +37 kb Cebpa enhancer for hematopoietic-specific Cebpa expression, with enhancer deletion leading to impaired myelopoiesis and potentially preleukemic progenitor expansion.
Data indicate that miR (show MLXIP ELISA Kits)-25 is a novel negative regulator of adipocyte differentiation and it suppressed 3T3-L1 adipogenesis by targeting KLF4 (show KLF4 ELISA Kits) and C/EBPalpha, which provides novel insights into the molecular mechanism of miRNA-mediated cellular differentiation.
MYB (show MYB ELISA Kits) and C/EBPalpha activities are inter-dependent in controlling Flt3 (show FLT3 ELISA Kits) expression to influence lineage commitment of multipotential progenitors.
Data indicate that white adipose tissue from IgE receptor FcR1-deficient Fcer1a (show FCER1A ELISA Kits)(-/-) mice showed an increased expression of CCAAT-enhancer-binding protein-alpha (C-EBPalpha) and peroxisome proliferator-activated receptor-gamma (PPARgamma (show PPARG ELISA Kits)).
miR (show MLXIP ELISA Kits)-223 regulates adipocyte and osteoblast differentiation through a novel C/EBPs/miR (show MLXIP ELISA Kits)-223/FGFR2 (show FGFR2 ELISA Kits) regulatory feedback loop.
Data (including data from studies in transgenic/mutant mice) suggest Cebpa (CCAAT-enhancer binding protein alpha) in myeloid cells is down-regulated in type 2 diabetes resulting in poor maturation of Gr-1 (show GSR ELISA Kits)+ (chemokine receptor (show CCR1 ELISA Kits)) myeloid cells.
C/EBPalpha is required for the increased lipogenesis. C/EBPalpha plays a role in mediating the lipogenic effects of hepatic Trib1 (show TRIB1 ELISA Kits) deletion.
C/ebpalpha plays a role in liver growth regulation via the p53 (show TP53 ELISA Kits) pathway.
Dnmt1 (show DNMT1 ELISA Kits) is required for hematopoietic stem and progenitor cells maintenance via cebpa regulation during definitive hematopoiesis in zebrafish
Data suggest that upregulation of 10-formyltetrahydrofolate dehydrogenase (FDH (show ALDH1L1 ELISA Kits)) involving CEBPalpha helps relieve embryonic oxidative stress induced (show SQSTM1 ELISA Kits) by ethanol exposure.
Bmi1 (show BMI1 ELISA Kits) acts immediately downstream of CCAAT enhancer binding protein-alpha to regulate the survival and self-renewal of hematopoietic stem cells and contribute to the erythropoietic dysplasia.
Results provide first evidence that sumoylation of Cebp-alpha (via SUMO1 (show SUMO1 ELISA Kits), SUMO2 (show SUMO2 ELISA Kits), and SUMO3 (show SUMO3 ELISA Kits)) might contribute to cell fate decision of myelo-erythroid progenitor cells in intermediate cell mass during primitive [extramedullary] hematopoiesis.
An evolutionarily conserved PTEN-C/EBPalpha-CTNNA1 (show CTNNA1 ELISA Kits) axis controls myeloid development and transformation.
a C/EBP recognition sequence in the proximal promoter region of C/EBPalpha is essential for IL-6 (show IL6 ELISA Kits)-mediated repression
These results suggest that the CEBPA gene is a strong candidate gene that affects carcass traits in Qinchuan cattle.
Expressions of C-EBPalpha and myostatin (show MSTN ELISA Kits) in muscles were higher in the concentrate-fed group than in the grass hay (show GTF2H5 ELISA Kits)-fed group.
C/EBPalpha is an essential regulatory factor for perilipin5 transcription and suggest that fasting stimulates perilipin5 transcription through influencing C/EBPalpha expression.
The differential expression of specific CEBPA/B isoforms observed in maturing follicles and CL may contribute to changes in follicular cell differentiation and increasing steroidogenic capacity.
The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. The encoded protein has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, the encoded protein can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells.
CCAAT/enhancer-binding protein alpha
, C/EBP alpha
, CAAT/enhancer-binding protein DNA-binding protein
, CAAT/enhancer-binding protein, DNA-binding protein
, CCAAT/enhancer binding protein, alpha
, c/EBP alpha
, CCAAT/enhancer binding protein alpha