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CCAAT/enhancer Binding Protein (C/EBP), epsilon Proteins (CEBPE)

The protein encoded by CEBPE is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. Additionally we are shipping CCAAT/enhancer Binding Protein (C/EBP), epsilon Antibodies (79) and CCAAT/enhancer Binding Protein (C/EBP), epsilon Kits (16) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CEBPE 1053 Q15744
CEBPE 110794 Q6PZD9
CEBPE 25410 P56261
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Top CCAAT/enhancer Binding Protein (C/EBP), epsilon Proteins at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
Yeast Sheep His tag   1 mg Log in to see 56 to 66 Days
$2,737.17
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,737.17
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 9 to 11 Days
$229.85
Details

CEBPE Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

Rat (Rattus)

More Proteins for CCAAT/enhancer Binding Protein (C/EBP), epsilon (CEBPE) Interaction Partners

Human CCAAT/enhancer Binding Protein (C/EBP), epsilon (CEBPE) interaction partners

  1. variants within IKZF1 (show IKZF1 Proteins), ARID5B (show ARID5B Proteins), and CEBPE were associated with increased acute lymphoblastic leukemia (ALL) risk, and the effects for ARID5B (show ARID5B Proteins) and CEBPE were most prominent in high-hyperdiploid ALL subtype in the California Hispanic population

  2. Data indicate no significant associations of transcription factors rs4132601 (IKZF1), rs7089424 (ARID5B) and rs2239633 (CEBPE) with risk of pediatric non-Hodgkin lymphoma (NHL).

  3. our study provided evidence that CEBPE rs2239633 variant is associated with decreased risk of childhood B-cell ALL in Europeans.

  4. A novel in-frame deletion in the leucine zipper domain of CEBPE leads to neutrophil-specific granule deficiency.

  5. During neutrophil development, acetylation of lysines 121 and 198 were found to be crucial for terminal neutrophil differentiation and the expression of neutrophil-specific granule proteins, including lactoferrin (show LTF Proteins) and collagenase.

  6. Studies indicate that the CCAAT/enhancer binding protein-epsilon (CEBPE) rs2239633 polymorphism was significantly associated with childhood acute lymphoblastic leukemiaacute lymphoblastic leukemia (ALL) risk.

  7. The expression profiles of transcription factors, C/EBP(alpha (show CEBPA Proteins), beta, epsilon) and PU.1 were further evaluated in the cells after treatment with ATRA and VPA.

  8. study found that previously identified childhood acute lymphoblastic leukemia susceptibility loci in ARID5B (show ARID5B Proteins) and CEBPE show consistent risk effects across both Hispanic and non-Hispanic White populations, providing compelling supportive evidence for susceptibility at these loci

  9. Germline variants in IKZF1 (show IKZF1 Proteins), ARID5B (show ARID5B Proteins), and CEBPE as risk factors for adult-onset acute lymphoblastic leukemia: an analysis from the GMALL study group.

  10. miR (show MLXIP Proteins)-130a is important for the regulation of the timed expression of C/EBP-epsilon during granulopoiesis.

Mouse (Murine) CCAAT/enhancer Binding Protein (C/EBP), epsilon (CEBPE) interaction partners

  1. study suggests that the myeloid specific factor C/EBPepsilon is involved in systemic lipid metabolism and that silencing of C/EBPepsilon could decrease the development of atherosclerosis.

  2. in the absence of CCAAT enhancer binding protein epsilon (C/EBPepsilon), there is not only incomplete differentiation of granulocytes, but myelopoiesis is disrupted and neutrophils have abnormal chemotaxis

  3. C/EBP epsilon gene as an important transcription factor required for normal function and development of macrophages.

  4. C/EBPepsilon interacts with Rb and E2F1 (show E2F1 Proteins) during granulocytic differentiation

  5. in the later stages of myeloid development, MMP8 (show MMP8 Proteins) and other SGP genes are coordinately upregulated, and members of the C/EBP (show CEBPA Proteins) family, in particular C/EBPalpha (show CEBPA Proteins) and C/EBPepsilon, play specific and unique roles in upregulating their expression

  6. Gfi-1 down-regulates C/EBPepsilon expression; increased expression of C/EBPepsilon as a consequence of loss of Gfi-1 function may be deleterious to the proliferation and survival of early myeloid cells

  7. the N terminus of C/EBPepsilon is solely responsible for most aspects of myeloid differentiation, and these events are differentially affected by c-Myc (show MYC Proteins)

  8. the requirement for C/EBP epsilon in mediating BPI (show BPI Proteins) gene expression in myeloid cells in vitro and in vivo.

  9. The type IV isoform of PML (show PML Proteins) interacted with PU.1, promoted its association with p300 (show NOTCH1 Proteins), and then enhanced PU.1-induced transcription and granulocytic differentiation and PU.1 directly activates the transcription of the C/EBPepsilon gene.

  10. Phosphorylation of PML (show PML Proteins) was required for stimulating C/EBP epsilon-dependent transcription and accelerating C/EBP epsilon-induced granulocytic differentiation.

CCAAT/enhancer Binding Protein (C/EBP), epsilon (CEBPE) Protein Profile

Protein Summary

The protein encoded by this gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP-delta. The encoded protein may be essential for terminal differentiation and functional maturation of committed granulocyte progenitor cells. Mutations in this gene have been associated with Specific Granule Deficiency, a rare congenital disorder. Multiple variants of this gene have been described, but the full-length nature of only one has been determined.

Gene names and symbols associated with CEBPE

  • CCAAT/enhancer binding protein (C/EBP), epsilon (CEBPE)
  • CCAAT/enhancer binding protein (C/EBP), epsilon (cebpe)
  • CCAAT/enhancer binding protein (C/EBP), epsilon (Cebpe)
  • CCAAT/enhancer-binding protein epsilon-like (LOC100157564)
  • CCAAT/enhancer-binding protein epsilon-like (LOC100338769)
  • C/EBP-epsilon protein
  • C/EBPe protein
  • C/EPBe protein
  • CEBPE protein
  • CRP1 protein
  • Gm294 protein

Protein level used designations for CEBPE

CCAAT/enhancer binding protein (C/EBP), epsilon , CCAAT/enhancer-binding protein epsilon , CCAAT/enhancer binding protein epsilon , c/ebp-epsilon , c/EBP epsilon , C/EBP-related protein 1 , C/EBPepsilon , CCAAT/enhancer binding protein , epsilon , c/EBP-related protein 1

GENE ID SPECIES
490607 Canis lupus familiaris
534346 Bos taurus
713442 Macaca mulatta
743538 Pan troglodytes
100038238 Xenopus (Silurana) tropicalis
100052512 Equus caballus
1053 Homo sapiens
110794 Mus musculus
25410 Rattus norvegicus
101122954 Ovis aries
100729561 Cavia porcellus
100157564 Sus scrofa
100338769 Oryctolagus cuniculus
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