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anti-CCCTC-Binding Factor (Zinc Finger Protein) (CTCF) Antibodies

CTCF is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. Additionally we are shipping CTCF Proteins (11) and CTCF Kits (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CTCF 13018 Q61164
CTCF 10664 P49711
CTCF 83726 Q9R1D1
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Top anti-CTCF Antibodies at antibodies-online.com

Showing 10 out of 87 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated ChIP, WB Chromatin Immunoprecipitation (ChIP) Using CTCF Antibody - N-terminal region (ARP38820_P050) and HCT116 Cells 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated ChIP, WB WB Suggested Anti-CTCF Antibody Titration: 0.2-1 ug/mlPositive Control: Transfected 293T Chromatin Immunoprecipitation (ChIP) Using CTCF Antibody - N-terminal region (P100757_P050) and HCT116 Cells 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated IF, WB Western blot analysis of CTCF on a Jurkat cell lysate (Human T-cell leukemia, ATCC TIB-152). Lane 1, 1:500, lane 2: 1: 1000, lane 3: 1: 2000 dilution of the mouse anti-CTCF antibody. Immunofluorescence staining of A431 cells (Human epithelial carcinoma, ATCC CRL-1555). 50 μg Log in to see 5 to 6 Days
$154.07
Details
Cow Rabbit Un-conjugated WB   100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated ELISA, WB Figure 1: Western blot analysis using CTCF mouse mAb against A31 (1), MCF-7 (2), Hela (3), HCT116 (4), Jurkat (5), NIH/3T3 (6), and Cos7 (7) cell lysate. 100 μL Log in to see 3 to 4 Days
$393.80
Details
Human Rabbit Un-conjugated IP 100 μL Log in to see 7 to 9 Days
$486.94
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-CTCF Picoband antibody, IHC(P) IHC(P): Human Lung Cancer Tissue Anti-CTCF Picoband antibody, IHC(P) IHC(P): Mouse Intestine Tissue 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated ELISA, WB Anti-CTCF in Western Blot using Immunochemical affinity purified Anti-CTCF antibody shows detection of CTCF in H929 nuclear cell lysates. Primary antibody was diluted to 1.2 µg/mL. 3% BSA from p/n BSA-30 (Bovine Serum Albumin Solution) was used for blocking. Secondary antibody anti-Rabbit IgG was used at 1:5,000. 25 μL Log in to see 2 to 3 Days
$135.00
Details
Human Rabbit Un-conjugated ChIP, ICC, IF, IHC, IHC (p), IP, WB Immunohistochemistry-Paraffin: CTCF Antibody [ABIN4300770] - FFPE sections of human ovarian carcinoma (left) and mouse renal cell carcinoma (right). Antibody: Affinity purified rabbit anti-CTCF used at a dilution of 1:100 (2ug/ml). Detection: DAB Western Blot: CTCF Antibody [ABIN4300770] - Samples: A) Whole cell lysate (5, 15 and 50 ug for WB; 1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-CTCF antibody ABIN4300770 lot 2) used for WB at 0.1 ug/ml (A) and 1 ug/ml (B) and used for IP at 3 ug/mg lysate. Detection: Chemiluminescence with exposure times of 30 seconds (A) and 3 minutes (B). 0.1 mL Log in to see 7 to 9 Days
$486.94
Details
Human Mouse Un-conjugated EIA, WB 0.1 mL Log in to see 6 to 8 Days
$390.50
Details

CTCF Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
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Rat (Rattus) , ,
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Top referenced anti-CTCF Antibodies

  1. Human Monoclonal CTCF Primary Antibody for IF, WB - ABIN968757 : Bell, West, Felsenfeld: The protein CTCF is required for the enhancer blocking activity of vertebrate insulators. in Cell 1999 (PubMed)
    Show all 4 references for ABIN968757

  2. Human Monoclonal CTCF Primary Antibody for EIA, WB - ABIN1106844 : Grbesa, Marinkovic, Ivkic, Kruslin, Novak-Kujundzic, Pegan, Bogdanovic, Bedekovic, Gall-Troselj: Loss of imprinting of IGF2 and H19, loss of heterozygosity of IGF2R and CTCF, and Helicobacter pylori infection in laryngeal squamous cell carcinoma. in Journal of molecular medicine (Berlin, Germany) 2008 (PubMed)
    Show all 3 references for ABIN1106844

  3. Human Monoclonal CTCF Primary Antibody for ELISA, WB - ABIN969071 : Majumder, Gomez, Chadwick, Boss: The insulator factor CTCF controls MHC class II gene expression and is required for the formation of long-distance chromatin interactions. in The Journal of experimental medicine 2008 (PubMed)
    Show all 3 references for ABIN969071

  4. Cow (Bovine) Polyclonal CTCF Primary Antibody for ChIP, WB - ABIN2792571 : Defossez, Kelly, Filion, Pérez-Torrado, Magdinier, Menoni, Nordgaard, Daniel, Gilson: The human enhancer blocker CTC-binding factor interacts with the transcription factor Kaiso. in The Journal of biological chemistry 2005 (PubMed)

  5. Human Polyclonal CTCF Primary Antibody for IP - ABIN153008 : Lai, Fatemi, Dhasarathy, Malone, Sobol, Geigerman, Jaye, Mav, Shah, Li, Wade: DNA methylation prevents CTCF-mediated silencing of the oncogene BCL6 in B cell lymphomas. in The Journal of experimental medicine 2010 (PubMed)

  6. Human Polyclonal CTCF Primary Antibody for ChIP, ICC - ABIN4300770 : Martínez, Cruz, Lu, Plasschaert, Deng, Rivera-Molina, Bartolomei, Lieberman, Tang: CTCF binding to the first intron of the major immediate early (MIE) gene of human cytomegalovirus (HCMV) negatively regulates MIE gene expression and HCMV replication. in Journal of virology 2014 (PubMed)

More Antibodies against CTCF Interaction Partners

Zebrafish CCCTC-Binding Factor (Zinc Finger Protein) (CTCF) interaction partners

  1. We propose that cohesin and CTCF have distinct functions in the regulation of runx1 (show RUNX1 Antibodies) during zebrafish embryogenesis.

  2. Data conclude that CTCF modulates MRF (show C11orf9 Antibodies) functional interactions in the orchestration of myogenesis.

Mouse (Murine) CCCTC-Binding Factor (Zinc Finger Protein) (CTCF) interaction partners

  1. Our study also identified the imprinting control region (ICR) of H19 (show NCKAP1 Antibodies) as a genomic target. According to the results, PEG3 (show PEG3 Antibodies) binds to a specific sequence motif located between the 3(rd) and 4(th) CTCF binding sites of the H19 (show NCKAP1 Antibodies)-ICR. PEG3 (show PEG3 Antibodies) also binds to the active maternal allele of the H19 (show NCKAP1 Antibodies)-ICR.

  2. Using circular chromosome conformation capture sequencing, we systematically examined the interacting loci of a Bmal1 (show ARNTL Antibodies)-bound super-enhancer upstream of a clock gene Nr1d1 (show NR1D1 Antibodies) in mouse liver. Global analysis showed that cohesin-CTCF co-binding sites tend to insulate the phases of circadian oscillating genes while cohesin-non-CTCF sites are associated with high circadian rhythmicity of transcription.

  3. data demonstrate a reciprocal relationship between Hmgb2 (show HMGB2 Antibodies) and Ctcf in controlling aspects of chromatin structure and gene expression.

  4. in addition to mediating long-range chromatin interactions, CTCF influences intricate configuration of chromatin loops that govern functional interactions between elements.

  5. TGF-beta (show TGFB1 Antibodies)/beta2-spectrin/CTCF-regulated tumor suppression in human stem cell disorder Beckwith-Wiedemann syndrome.

  6. Results indicate that CTCF binding polarity plays a functional role in the formation of higher-order chromatin structure.

  7. Firre is X-linked and expressed from a macrosatellite repeat locus associated with a cluster of CTCF and cohesin binding sites, and is preferentially located adjacent to the nucleolus

  8. CTCF controls the homeostatic maintenance and migration of Langerhans cells.

  9. MyoD (show MYOD1 Antibodies) affects chromatin looping at CCCTC-binding factor-binding sites represents the first evidence that a differentiation factor regulates chromatin-loop dynamics

  10. Findings establish CTCF as a prominent tumor-suppressor gene and point to CTCF-mediated epigenetic stability as a major barrier to neoplastic progression.

Human CCCTC-Binding Factor (Zinc Finger Protein) (CTCF) interaction partners

  1. we investigated the cell-type specificities of CTCF sites related to these functions across five cell types. Our study provides new insights into the multivalent functions of CTCF in the human genome

  2. The results indicate that the initial chromatin conformation affects subsequent RA-induced HOXA gene activation. Our study uncovers that a removable insulator spatiotemporally switches higher-order chromatin and multiple gene activities via cooperation of CTCF and key transcription factors.

  3. we find no evidence for selection driving these distinctive patterns of mutation. The mutational load at CTCF-binding sites is substantially determined by replication timing and the mutational signature of the tumor in question, suggesting that selectively neutral processes underlie the unusual mutation patterns.

  4. data demonstrate a reciprocal relationship between Hmgb2 (show HMGB2 Antibodies) and Ctcf in controlling aspects of chromatin structure and gene expression.

  5. Study described the formation of mutually exclusive complexes of ENY2 (show ENY2 Antibodies) with insulator proteins and Sgfl1-a component of the SAGA complex, direct binding partner for ENY2 (show ENY2 Antibodies)

  6. This is supported by the depletion of CTCF in glioblastoma cells affecting the expression levels of NOTCH2 (show NOTCH2 Antibodies) as a target of miR (show MLXIP Antibodies)-181c. CONCLUSION: Together, our results point to the epigenetic role of CTCF in the regulation of microRNAs implicated in tumorigenesis

  7. Our data show that aberrant epigenetic inactivation of DUSP2 (show DUSP2 Antibodies) occurs in carcinogenesis and that CTCF is involved in the epigenetic regulation of DUSP2 (show DUSP2 Antibodies) expression.

  8. Mutational analysis highlighted a potential role for CTCF, a crucial regulator of long-range chromatin interactions, in head and neck cancer progression.

  9. CTCF and cohesins shape the genome during evolution. (Review)

  10. The action of SNF2H (show SMARCA5 Antibodies) at CTCF sites is functionally important as depletion of CTCF or SNF2H (show SMARCA5 Antibodies) affects transcription of a common group of genes.

CTCF Antigen Profile

Protein Summary

This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear protein is able to use different combinations of the ZF domains to bind different DNA target sequences and proteins. Depending upon the context of the site, the protein can bind a histone acetyltransferase (HAT)-containing complex and function as a transcriptional activator or bind a histone deacetylase (HDAC)-containing complex and function as a transcriptional repressor. If the protein is bound to a transcriptional insulator element, it can block communication between enhancers and upstream promoters, thereby regulating imprinted expression. Mutations in this gene have been associated with invasive breast cancers, prostate cancers, and Wilms' tumors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with CTCF

  • CCCTC-binding factor (zinc finger protein) (CTCF) antibody
  • CCCTC-binding factor (zinc finger protein) (ctcf) antibody
  • CCCTC-binding factor (zinc finger protein) (LOC100224119) antibody
  • CCCTC-binding factor (Ctcf) antibody
  • CCCTC-binding factor (zinc finger protein) (Ctcf) antibody
  • AW108038 antibody
  • CTCF antibody
  • im:7152666 antibody
  • xctcf antibody

Protein level used designations for CTCF

transcriptional repressor CTCF , CCCTC-binding factor (zinc finger protein) , transcriptional repressor CTCF-like , 11-zinc finger protein , CTCFL paralog , 11 zinc finger transcriptional repressor

GENE ID SPECIES
100053363 Equus caballus
415104 Danio rerio
454169 Pan troglodytes
100101689 Xenopus (Silurana) tropicalis
100224119 Taeniopygia guttata
100350641 Oryctolagus cuniculus
100465401 Ailuropoda melanoleuca
13018 Mus musculus
10664 Homo sapiens
396274 Gallus gallus
479684 Canis lupus familiaris
517097 Bos taurus
83726 Rattus norvegicus
100623274 Sus scrofa
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