anti-CCCTC-Binding Factor (Zinc Finger Protein) (CTCF) Antibodies

CTCF is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. Additionally we are shipping CTCF Proteins (11) and CTCF Kits (9) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CTCF 13018 Q61164
CTCF 10664 P49711
CTCF 83726 Q9R1D1
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Top anti-CTCF Antibodies at antibodies-online.com

Showing 10 out of 91 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated ChIP, WB Chromatin Immunoprecipitation (ChIP) Using CTCF Antibody - N-terminal region (ARP38820_P050) and HCT116 Cells 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated ChIP, WB <b>WB Suggested Anti-CTCF Antibody Titration: </b>0.2-1 ug/ml<br><b>Positive Control: </b>Transfected 293T Chromatin Immunoprecipitation (ChIP) Using CTCF Antibody - N-terminal region (P100757_P050) and HCT116 Cells 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB Host: Rabbit Target Name: CTCF Sample Tissue: Mouse Spleen Antibody Dilution: 1ug/ml Host: Rabbit Target Name: CTCF Sample Tissue: Mouse Testis Antibody Dilution: 1ug/ml 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-CTCF Picoband antibody, IHC(P) IHC(P): Human Lung Cancer Tissue Anti-CTCF Picoband antibody, IHC(P) IHC(P): Mouse Intestine Tissue 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Mouse Un-conjugated IF, WB Western blot analysis of CTCF on a Jurkat cell lysate (Human T-cell leukemia, ATCC TIB-152). Lane 1, 1:500, lane 2: 1: 1000, lane 3: 1: 2000 dilution of the mouse anti-CTCF antibody. Immunofluorescence staining of A431 cells (Human epithelial carcinoma, ATCC CRL-1555). 50 μg Log in to see 6 to 8 Days
$154.07
Details
Human Rabbit Un-conjugated IP 100 μL Log in to see 7 to 9 Days
$486.94
Details
Bat Rabbit Un-conjugated IHC (p), WB Human Lung (formalin-fixed, paraffin-embedded) stained with CTCF antibody ABIN214093 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Human Skin (formalin-fixed, paraffin-embedded) stained with CTCF antibody ABIN214093 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 7 to 9 Days
$676.50
Details
Human Mouse Un-conjugated ELISA, WB Figure 1: Western blot analysis using CTCF mouse mAb against A31 (1), MCF-7 (2), Hela (3), HCT116 (4), Jurkat (5), NIH/3T3 (6), and Cos7 (7) cell lysate. 100 μL Log in to see 2 to 3 Days
$393.80
Details
Bat Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB Anti-CTCF in Western Blot using Immunochemical affinity purified Anti-CTCF antibody shows detection of CTCF in H929 nuclear cell lysates. Primary antibody was diluted to 1.2 µg/mL. 3% BSA from p/n BSA-30 (Bovine Serum Albumin Solution) was used for blocking. Secondary antibody anti-Rabbit IgG was used at 1:5,000. 25 μL Log in to see 1 to 2 Days
$135.00
Details

CTCF Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
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Top referenced anti-CTCF Antibodies

  1. Human Monoclonal CTCF Primary Antibody for IF, WB - ABIN968757 : Bell, West, Felsenfeld: The protein CTCF is required for the enhancer blocking activity of vertebrate insulators. in Cell 1999 (PubMed)
    Show all 4 Pubmed References

  2. Human Monoclonal CTCF Primary Antibody for IF, WB - ABIN968758 : Filippova, Fagerlie, Klenova, Myers, Dehner, Goodwin, Neiman, Collins, Lobanenkov: An exceptionally conserved transcriptional repressor, CTCF, employs different combinations of zinc fingers to bind diverged promoter sequences of avian and mammalian c-myc oncogenes. in Molecular and cellular biology 1996 (PubMed)
    Show all 4 Pubmed References

  3. Human Monoclonal CTCF Primary Antibody for ELISA, WB - ABIN969071 : Grbesa, Marinkovic, Ivkic, Kruslin, Novak-Kujundzic, Pegan, Bogdanovic, Bedekovic, Gall-Troselj: Loss of imprinting of IGF2 and H19, loss of heterozygosity of IGF2R and CTCF, and Helicobacter pylori infection in laryngeal squamous cell carcinoma. in Journal of molecular medicine (Berlin, Germany) 2008 (PubMed)
    Show all 3 Pubmed References

  4. Human Polyclonal CTCF Primary Antibody for IP - ABIN153008 : Lai, Fatemi, Dhasarathy, Malone, Sobol, Geigerman, Jaye, Mav, Shah, Li, Wade: DNA methylation prevents CTCF-mediated silencing of the oncogene BCL6 in B cell lymphomas. in The Journal of experimental medicine 2010 (PubMed)

  5. Human Polyclonal CTCF Primary Antibody for ChIPSeq, ChIP - ABIN2668282 : Moriguchi, Yu, Takai, Hayashi, Satoh, Suzuki, Ohneda, Yamamoto: The Human GATA1 Gene Retains a 5' Insulator That Maintains Chromosomal Architecture and GATA1 Expression Levels in Splenic Erythroblasts. in Molecular and cellular biology 2015 (PubMed)

  6. Human Monoclonal CTCF Primary Antibody for ELISA, WB - ABIN965942 : Majumder, Gomez, Chadwick, Boss: The insulator factor CTCF controls MHC class II gene expression and is required for the formation of long-distance chromatin interactions. in The Journal of experimental medicine 2008 (PubMed)
    Show all 3 Pubmed References

  7. Human Polyclonal CTCF Primary Antibody for ChIP, ICC - ABIN4300770 : Martínez, Cruz, Lu, Plasschaert, Deng, Rivera-Molina, Bartolomei, Lieberman, Tang: CTCF binding to the first intron of the major immediate early (MIE) gene of human cytomegalovirus (HCMV) negatively regulates MIE gene expression and HCMV replication. in Journal of virology 2014 (PubMed)

More Antibodies against CTCF Interaction Partners

Zebrafish CCCTC-Binding Factor (Zinc Finger Protein) (CTCF) interaction partners

  1. We propose that cohesin and CTCF have distinct functions in the regulation of runx1 (show RUNX1 Antibodies) during zebrafish embryogenesis.

  2. Data conclude that CTCF modulates MRF (show C11orf9 Antibodies) functional interactions in the orchestration of myogenesis.

Mouse (Murine) CCCTC-Binding Factor (Zinc Finger Protein) (CTCF) interaction partners

  1. CTCF mediates local regulatory interactions to coordinate transcriptional programs controlling transitions in morphology and function during heart development.

  2. Long-range promoter-enhancer interaction mediated by CTCF plays important roles in controlling the cell-to-cell variation of gene expression in mammalian cells.

  3. n keratinocytes, the promoter-enhancer anchoring regions in the gene-rich transcriptionally active TADs are enriched for the binding of chromatin architectural proteins CTCF, Rad21 (show RAD21 Antibodies) and chromatin remodeler Brg1 (show SMARCA4 Antibodies). In contrast to gene-rich TADs, gene-poor TADs show preferential spatial contacts with each other, do not contain active enhancers and show decreased binding of CTCF, Rad21 (show RAD21 Antibodies) and Brg1 (show SMARCA4 Antibodies) in keratinocytes

  4. CTCF mediated chromatin structural modulation and regulates Hoxc gene expression.

  5. CTCF can regulate V(D)J recombination by segregating recombination signal sequences (RSSs) into distinct loop domains and inhibiting RSS (show GRB10 Antibodies) synapsis, independent of any effects on transcription, RSS (show GRB10 Antibodies) accessibility, and RAG recombinase (show RAG1 Antibodies) tracking

  6. this study shows that CTCF serves to translate alpha-ketoglutarate-sensitive metabolic changes into context-dependent differentiation gene programs

  7. CTCF-cohesin-mediated chromatin architecture delimits enhancer interactions and function in vivo.

  8. ERCC1 (show ERCC1 Antibodies)-XPF (show ERCC4 Antibodies) cooperates with CTCF and cohesin to facilitate the developmental silencing of imprinted genes and that persistent DNA damage triggers chromatin changes that affect gene expression programs associated with NER (show NR1H2 Antibodies) disorders.

  9. BRD2 (show BRD2 Antibodies) acts to augment the boundary function of CTCF both by limiting the spread or range of enhancer activity and by physically preventing the formation of cross-boundary contacts genome-wide.

  10. Functional assessment of CTCF sites at cytokine-sensing mammary enhancers using CRISPR/Cas9 gene editing in mice has been reported.

Human CCCTC-Binding Factor (Zinc Finger Protein) (CTCF) interaction partners

  1. CTCF-mediated long-range interactions are integral for a multitude of topological features of interphase chromatin, such as the formation of topologically associated domains, domain insulation, enhancer blocking and even enhancer function.

  2. Authors have identified two novel pro-tumorigenic roles (promoting cell survival and altering cell polarity) for genetic alterations of CTCF in endometrial cancer.

  3. Describe several protein-DNA complex structures of a human CTCF tandem zinc-finger array, explaining the adaptability of CTCF to sequence variations and the positiondependent effect of differential DNA methylation (show HELLS Antibodies) at two cytosine residues, and revealing a potential function of C-terminal ZF8 and ZF9 (show KLF6 Antibodies) spanning across the DNA phosphate backbone.

  4. CCCTC-binding factor (CTCF) targets the binding sites within MYCN (show MYCN Antibodies) promoter to facilitate its expression in neuroblastoma (show ARHGEF16 Antibodies) (NB) cells.

  5. we review recent high-resolution chromosome conformation capture and functional studies that have informed models of the spatial and regulatory compartmentalization of mammalian genomes, and discuss mechanistic models for how CTCF and cohesin control the functional architecture of mammalian chromosomes.

  6. GAD1 (show GAD1 Antibodies) is reactivated by DNA methylation (show HELLS Antibodies), which provided a model for DNA methylation (show HELLS Antibodies) and the active orchestration of oncogenic gene expression by CTCF in cancer cells.

  7. epigenetic factor CTCF-mediated chromatin remodeling regulates interactions between eye-specific PAX6 (show PAX6 Antibodies) and those genes that are induced/associated with cell differentiation to modulate corneal epithelial cell-specific differentiation

  8. Rta (show RBM9 Antibodies)-mediated decreased binding of CTCF in the viral genome is concurrent with virus reactivation. Via interfering with CTCF binding, in the host genome Rta (show RBM9 Antibodies) can function as a transcriptional repressor for gene silencing.

  9. although we were unable to detect HD-associated DNA methylation (show HELLS Antibodies) alterations at queried sites, we found that DNA methylation (show HELLS Antibodies) may be correlated to the age of disease onset in cortex tissues. Moreover, our data suggest that DNA methylation (show HELLS Antibodies) may, in part, contribute to tissue-specific HTT (show HTT Antibodies) transcription through differential CTCF occupancy.

  10. Data support the hypothesis that CTCF and cohesin SA-1 (show STAG1 Antibodies) have multiple roles in the regulation of gene expression during erythropoiesis.

CTCF Antigen Profile

Protein Summary

This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear protein is able to use different combinations of the ZF domains to bind different DNA target sequences and proteins. Depending upon the context of the site, the protein can bind a histone acetyltransferase (HAT)-containing complex and function as a transcriptional activator or bind a histone deacetylase (HDAC)-containing complex and function as a transcriptional repressor. If the protein is bound to a transcriptional insulator element, it can block communication between enhancers and upstream promoters, thereby regulating imprinted expression. Mutations in this gene have been associated with invasive breast cancers, prostate cancers, and Wilms' tumors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with CTCF

  • CCCTC-binding factor (zinc finger protein) (CTCF) antibody
  • CCCTC-binding factor (zinc finger protein) (ctcf) antibody
  • CCCTC-binding factor (zinc finger protein) (LOC100224119) antibody
  • CCCTC-binding factor (Ctcf) antibody
  • CCCTC-binding factor (zinc finger protein) (Ctcf) antibody
  • AW108038 antibody
  • CTCF antibody
  • im:7152666 antibody
  • xctcf antibody

Protein level used designations for CTCF

transcriptional repressor CTCF , CCCTC-binding factor (zinc finger protein) , transcriptional repressor CTCF-like , 11-zinc finger protein , CTCFL paralog , 11 zinc finger transcriptional repressor

GENE ID SPECIES
100053363 Equus caballus
415104 Danio rerio
454169 Pan troglodytes
100101689 Xenopus (Silurana) tropicalis
100224119 Taeniopygia guttata
100350641 Oryctolagus cuniculus
100465401 Ailuropoda melanoleuca
13018 Mus musculus
10664 Homo sapiens
396274 Gallus gallus
479684 Canis lupus familiaris
517097 Bos taurus
83726 Rattus norvegicus
100623274 Sus scrofa
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