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CNBP encodes a nucleic-acid binding protein with seven zinc-finger domains. Additionally we are shipping CNBP Antibodies (88) and CNBP Proteins (12) and many more products for this protein.
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High CNBP expression is associated with Medulloblastoma.
CNBP overexpression caused increase of cell death and suppression of cell metastasis through its induction of G-quadruplex formation in the promoter of hnRNP K (show HNRNPK ELISA Kits) resulting in hnRNP K (show HNRNPK ELISA Kits) down-regulation
Arginine methylation of CNBP in the RG motif does not change the subcellular localization but regulates its RNA binding activity.
CNBP are novel antigens for SLE patients and the recognition of CNBP might be differentiated dependent on the level of arginine methylation.
suggested a new possibility of CNBP as a potential anti-cancer target based on CNBP's biological function in c-myc (show MYC ELISA Kits) transcription
CNBP associates with the poly(A) binding protein and accumulates in stress granules.
The co-segregation of Myotonic dystrophy type 2 with a recessive CLCN1 (show CLCN1 ELISA Kits) mutation provided the explanation for the unusual clinical findings for juvenile onset of myotonia in a 14-year-old female with Myotonic dystrophy type 2 and her affected mother
Myotonic dystrophy 2(autosomal dominant, multisystem disorder caused by a CCTG (show CCT3 ELISA Kits) tetranucleotide repeat expansion located in intron 1 of the zinc finger protein 9 gene (ZNF9 gene) on chromosome 3q 21.3.) described in Israeli Jewish European ancestry.
CCTG (show CCT3 ELISA Kits) repeat expansions in the CNBP gene are responsible for myotonic dystrophy type 2.
Study concludes that DM2 patients from the Netherlands, including a North-African family, harbor a common haplotype surrounding the ZNF9 gene.
CNBP up-regulates tbx2b and smarca5, and down-regulates wnt5b (show WNT5B ELISA Kits) gene expression.
expression of APP (show APP ELISA Kits)(Swe) in murine tissue induces a decrease in CNBP expression.
CNBP targets Myc (show MYC ELISA Kits) in rostral head formation, is essential for forebrain induction and specification.
This gene encodes a nucleic-acid binding protein with seven zinc-finger domains. The protein has a preference for binding single stranded DNA and RNA. The protein functions in cap-independent translation of ornithine decarboxylase mRNA, and may also function in sterol-mediated transcriptional regulation. A CCTG expansion in the first intron of this gene results in myotonic dystrophy type 2. Multiple transcript variants encoding different isoforms have been found for this gene.
cellular nucleic acid-binding protein
, zinc finger protein 9
, cellular nucleic acid binding protein
, erythroid differentiation-related
, sterol regulatory element-binding protein
, zinc finger protein 273
, zinc finger protein 9 (a cellular retroviral nucleic acid binding protein)
, cellular nucleic acid binding protein 1
, cellular nucleic acid binding protein a
, DNA binding protein