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CCR4-NOT Transcription Complex, Subunit 2 Proteins (CNOT2)

CNOT2 encodes a subunit of the multi-component CCR4-NOT complex. Additionally we are shipping CNOT2 Antibodies (104) and CNOT2 Kits (12) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CNOT2 4848 Q9NZN8
CNOT2 72068 Q8C5L3
Rat CNOT2 CNOT2 299805  
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Top CNOT2 Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 9 to 11 Days
$229.85
Details

CNOT2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for CCR4-NOT Transcription Complex, Subunit 2 (CNOT2) Interaction Partners

Human CCR4-NOT Transcription Complex, Subunit 2 (CNOT2) interaction partners

  1. The CNOT2-CNOT3 heterodimer is stabilized and tightly anchored to the surface of CNOT1 through an unexpected intertwined arrangement of peptide regions lacking defined secondary structure.

  2. Cnot1, Cnot2, and Cnot3 (show CNOT3 Proteins) represent a novel component of the core self-renewal and pluripotency circuitry conserved in mouse and human ESCs (show NR2E3 Proteins).

  3. human CNOT2 is important for maintaining the deadenylase activity and structural integrity of the CCR4 (show CCR4 Proteins)-NOT complex, thereby affecting cell viability.

  4. This study shows that SMRT/NCoR (show NCOR1 Proteins)-HDAC3 (show HDAC3 Proteins) complex is a cofactor of CNOT2-mediated repression and suggests that transcriptional regulation by the Ccr4 (show CCR4 Proteins)-Not complex involves regulation of chromatin modification.

  5. major repression function of CNOT2 is localized in a specialized protein motif, the Not-Box

  6. These findings suggest that CDK11 (show CDK11B Proteins) may contribute to apoptosis by regulating the activity of NOT2 independent of its kinase activity.

Mouse (Murine) CCR4-NOT Transcription Complex, Subunit 2 (CNOT2) interaction partners

  1. These data have uncovered a novel role of core components of the Ccr4 (show CCR4 Proteins)-Not complex as regulators of transition from partial to genuine induced pluripotent stem cells.

  2. Cnot1, Cnot2, and Cnot3 (show CNOT3 Proteins) represent a novel component of the core self-renewal and pluripotency circuitry conserved in mouse and human ESCs (show NR2E3 Proteins).

CNOT2 Protein Profile

Protein Summary

This gene encodes a subunit of the multi-component CCR4-NOT complex. The CCR4-NOT complex regulates mRNA synthesis and degradation and is also thought to be involved in mRNA splicing, transport and localization. The encoded protein interacts with histone deacetylases and functions as a repressor of polymerase II transcription. Alternatively spliced transcript variants have been observed for this gene.

Gene names and symbols associated with CNOT2

  • CCR4-NOT transcription complex, subunit 2 (CNOT2)
  • CCR4-NOT transcription complex, subunit 2 (LOC396117)
  • CCR4-NOT transcription complex, subunit 2 (cnot2)
  • CCR4-NOT transcription complex, subunit 2 (Cnot2)
  • zgc:162316 (zgc:162316)
  • 2600016M12Rik protein
  • 2810470K03Rik protein
  • AA537049 protein
  • AA959607 protein
  • AW557563 protein
  • C79650 protein
  • CDC36 protein
  • cnot2 protein
  • NOT2 protein
  • NOT2H protein

Protein level used designations for CNOT2

homeobox protein , CCR4-NOT transcription complex subunit 2 , CCR4-NOT transcription complex, subunit 2 , CCR4-NOT transcription complex subunit 2-like , CCR4-associated factor 2 , negative regulator of transcription 2

GENE ID SPECIES
100062938 Equus caballus
396117 Gallus gallus
100127821 Xenopus (Silurana) tropicalis
100173614 Pongo abelii
100398024 Callithrix jacchus
443622 Xenopus laevis
417851 Gallus gallus
4848 Homo sapiens
474446 Canis lupus familiaris
533945 Bos taurus
72068 Mus musculus
299805 Rattus norvegicus
100153354 Sus scrofa
100037372 Danio rerio
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