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CCR4-NOT Transcription Complex, Subunit 6 Proteins (CNOT6)

The protein encoded by CNOT6 is a subunit of the CCR4-NOT core transcriptional regulation complex. Additionally we are shipping CNOT6 Antibodies (34) and CNOT6 Kits (9) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CNOT6 57472 Q9ULM6
CNOT6 104625 Q8K3P5
Rat CNOT6 CNOT6 287249 Q6AXU9
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Top CNOT6 Proteins at antibodies-online.com

Showing 3 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

CNOT6 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for CCR4-NOT Transcription Complex, Subunit 6 (CNOT6) Interaction Partners

Human CCR4-NOT Transcription Complex, Subunit 6 (CNOT6) interaction partners

  1. miR (show MLXIP Proteins)-29c-3p promotes the senescence of Mesenchymal stem cells by targeting CNOT6 through p53 (show TP53 Proteins)-p21 (show CDKN1A Proteins) and p16-pRB (show RB1 Proteins) pathways.

  2. These results indicate that Caf1 (show CHAF1B Proteins) and Ccr4 (show CCR4 Proteins) cooperate in mRNA deadenylation and suggest that the enzyme activities of Caf1 (show CHAF1B Proteins) and Ccr4 (show CCR4 Proteins) are regulated via allosteric interactions within the nuclease (show DCLRE1C Proteins) module.

  3. Results identified CNOT6/CNOT6L (show CNOT6L Proteins) as a key regulator of insulin-like growth factor-binding protein 5 (show IGFBP5 Proteins), which mediates cell cycle arrest and senescence via a p53 (show TP53 Proteins)-dependent pathway.

  4. CCR4 (show CCR4 Proteins) and BTG2 (show BTG2 Proteins) interact and have a role in cell-cycle regulation

  5. CCR4 plays a role in the regulation of certain endogenous RARalpha target genes and RCD1 and CCR4 might mediate their function through their interaction with NIF-1

  6. hCCR4/cNOT6 targets DNA-damage response proteins

  7. Data show that Ccr4 (show CCR4 Proteins)-Not function in RNA splicing and nuclear export, and that CNOT6 binds CNOT8 (show CNOT8 Proteins) in yeast two-hybrid assays.

CNOT6 Protein Profile

Protein Summary

The protein encoded by this gene is a subunit of the CCR4-NOT core transcriptional regulation complex. The encoded protein has a 3'-5' RNase activity and prefers polyadenylated substates.

Gene names and symbols associated with CNOT6

  • CCR4-NOT transcription complex, subunit 6 (CNOT6)
  • CCR4-NOT transcription complex, subunit 6 (cnot6)
  • CCR4-NOT transcription complex subunit 6 (cnot6)
  • CCR4-NOT transcription complex, subunit 6 (Cnot6)
  • A230103N10Rik protein
  • AA407540 protein
  • AW456442 protein
  • CCR4 protein
  • RGD1310783 protein
  • wu:fa03c11 protein
  • wu:fc17f01 protein
  • zgc:65822 protein

Protein level used designations for CNOT6

CCR4-NOT transcription complex subunit 6 , CCR4-NOT transcription complex, subunit 6 , Cytoplasmic deadenylase , carbon catabolite repression 4 protein , carbon catabolite repressor protein 4 homolog , cytoplasmic deadenylase

GENE ID SPECIES
100516183 Sus scrofa
716286 Macaca mulatta
100195831 Salmo salar
100505426 Xenopus laevis
324048 Danio rerio
416293 Gallus gallus
57472 Homo sapiens
481463 Canis lupus familiaris
534707 Bos taurus
104625 Mus musculus
287249 Rattus norvegicus
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